The Extraneuronal Transporter for Monoamine Transmitters Exists in Cells Derived from Human Central Nervous System Glia

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

The fine structure of the nervous system: The neurons and supporting cells

1976 • 1,334 citations

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

1984 • 772 citations

Citalopram — Pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity

1982 • 589 citations

Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons.

1982 • 509 citations

Increased life expectancy resulting from addition of l-deprenyl to Madopar� treatment in Parkinson's disease: A longterm study

1985 • 437 citations

Localization of distinct monoamine oxidase a and monoamine oxidase b cell populations in human brainstem

1988 • 347 citations

Enzyme Kinetics: Behaviour and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems

1976 • 307 citations

Characterization of L-glutamate uptake into and release from astrocytes and neurons cultured from different brain regions

1982 • 298 citations

Inhibition of catecholamine Uptake₂ by steroids in the isolated rat heart

1970 • 285 citations

The mechanism of neuronal and extraneuronal transport of catecholamines

1976 • 279 citations

THE UPTAKE OF CATECHOL AMINES AT HIGH PERFUSION CONCENTRATIONS IN THE RAT ISOLATED HEART: A NOVEL CATECHOL AMINE UPTAKE PROCESS

1965 • 264 citations

The uptake of catechol amines at high perfusion concentrations in the rat isolated heart: a novel catechol amine uptake process

1997 • 249 citations

Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A.

1989 • 195 citations

Immunohistochemical demonstration of catechol-O-methyltransferase in mammalian brain

1979 • 139 citations

MPTP: A neurotoxin producing a parkinsonian syndrome

1987 • 133 citations

Tricyclic Antidepressants

1978 • 129 citations

Dopamine and norepinephrine uptake and metabolism by astroglial cells in culture

1981 • 124 citations

Neuronal and extraneuronal events in autonomic pharmacology

1984 • 111 citations

Transporter explosion: update on uptake

1992 • 110 citations

Astrocytes as a primary locus for the conversion MPTP into MPP+

1989 • 85 citations

High‐Affinity Uptake of [³H]Norepinephrine by Primary Astrocyte Cultures and Its Inhibition by Tricyclic Antidepressants

1983 • 81 citations

The extraneuronal uptake and localization of noradrenaline in the cat spleen and the effect on this of some drugs, of cold and of denervation

1970 • 81 citations

Amino acid and monoamine transport in primary astroglial cultures from defined brain regions

1985 • 78 citations

Cerebellar astroglial cells in primary culture: Expression of different morphological appearances and different ability to take up [3H]d-aspartate and [3H]GABA

1983 • 77 citations

Occurrence and functional significance of serotonin and catecholamine uptake by astrocytes

1986 • 74 citations

The extraneuronal transport mechanism for noradrenaline (uptake2) avidly transports 1-methyl-4-phenylpyridinium (MPP+)

1992 • 69 citations

The substrate specificity of uptake2 in the rat heart

1984 • 63 citations

Regional Differences in 5‐Hydroxytryptamine and Catecholamine Uptake in Primary Astrocyte Cultures

1986 • 57 citations

Extraneuronal noradrenaline transport (uptake2) in a human cell line (Caki-1 cells)

1990 • 53 citations

3H-normetanephrine uptake in rat brain slices. Relationship to extraneuronal accumulation of norepinephrine

1970 • 50 citations

Chemosensitivity of malignant human brain tumors

1983 • 49 citations

Cyanine-related compounds: a novel class of potent inhibitors of extraneuronal noradrenaline transport

1993 • 46 citations

Kinetic evidence for a common binding site for substrates and inhibitors of the neuronal noradrenaline carrier

1988 • 44 citations

Transport of monoamine and amino acid neurotransmitters by primary astroglial cultures

1985 • 34 citations

Sodium‐independent transport of noradrenaline in mouse and rat astrocytes in primary culture

1989 • 32 citations

Isocyanines and pseudoisocyanines as a novel class of potent noradrenaline-transport inhibitors: synthesis, detection, and biological activity

1993 • 31 citations

Comparison of two new inhibitors of catechol O‐methylation on striatal dopamine metabolism: a microdialysis study in rats

1994 • 29 citations

The kinetics of enzyme action and inhibition in intact tissues and tissue slices, with special reference to cholinesterase

1976 • 27 citations

The uptake and O-methylation of 3H-(�)-isoprenaline in rat cerebral cortex slices

1988 • 26 citations

Symptomatic Anti-Parkinsonian Effects of Monoamine Oxidase-B Inhibition: Comparison of Selegiline and Lazabemide

1993 • 22 citations

The force driving the extraneuronal transport mechanism for catecholamines (uptake2)

1992 • 21 citations

Plasticity of Astroglial Glutamate and γ‐Aminobutyric Acid Uptake in Cell Cultures Derived from Postnatal Mouse Cerebellum

1993 • 18 citations

Clinical pharmacology of the new COMT inhibitor CGP 28 014

1993 • 12 citations

The outward transport of catecholamines mediated by uptake2 of the rat heart

1985 • 12 citations

The influence of the density of adrenergic innervation on the extracellular steady-state concentration gradient for 3H-noradrenaline

1992 • 4 citations

Extraneuronal transport of noradrenaline

1994 • 2 citations

Cited By (0)

Loading...