Comparison of two new inhibitors of catechol O‐methylation on striatal dopamine metabolism: a microdialysis study in rats

Evidence for dopamine receptors mediating sedation in the mouse brain

1976 • 421 citations

Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors

1989 • 146 citations

Biochemical and pharmacological properties of a peripherally acting catechol-O-methyltransferase inhibitor entacapone

1992 • 145 citations

Catechol‐O‐methyltransferase‐Inhibiting Pyrocatechol Derivatives: Synthesis and Structure‐Activity Studies

1989 • 114 citations

Different in vivo properties of three new inhibitors of catechol O‐methyltransferase in the rat

1992 • 98 citations

The TiPS lecture: Functional aspects of the neuronal uptake of noradrenaline

1991 • 88 citations

Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study

1992 • 86 citations

Ro 40-7592: inhibition of COMT in rat brain and extracerebral tissues

1990 • 76 citations

Effects of Catechol‐O‐Methyltransferase Inhibitors and L‐3,4‐Dihydroxyphenylalanine With or Without Carbidopa on Extracellular Dopamine in Rat Striatum

1993 • 66 citations

Behavioural and neurochemical effects of Ro 40-7592, a new COMT inhibitor with a potential therapeutic activity in Parkinson's disease

1990 • 56 citations

Physical and chemical considerations in the in vitro calibration of microdialysis probes for biogenic amine neurotransmitters and metabolites

1990 • 47 citations

CGP 28014, a new inhibitor of cerebral catechol-O-methylation with a non-catechol structure

1990 • 39 citations

Catechol‐ O ‐methyltransferase inhibition increases striatal L‐dopa and dopamine

1992 • 36 citations

Effect of acute levodopa on brain catecholamines after selective MAO and COMT inhibition in male rats

1990 • 26 citations

Computerized rotometer apparatus for recording circling behavior.

1989 • 25 citations

Effects of the COMT inhibitor, CGP 28014, on plasma homovanillic acid and O-methylation of exogenous L-DOPA in the rat

1990 • 21 citations

Modulation of rat brain endogenous dopamine metabolism by new inhibitors of catechol O-methyltransferase

1993 • 16 citations

Effect of nitecapone and clorgyline, given intracerebro-ventricularly on L-dopa metabolism in the rat brain

1992 • 10 citations

Effect of the new selective COMT inhibitor CGP 28014 A on the formation of 3-O-methyldopa (3OMD) in plasma of healthy subjects

1990 • 9 citations

Neurochemical and psychomotor interactions of new selective COMT inhibitors with clorgyline and nomifensine in levodopa-treated rats and mice.

1992 • 5 citations