Protective Antiviral Cytotoxic T Cell Memory Is Most Efficiently Maintained by Restimulation Via Dendritic Cells

Dendritic cells and the control of immunity

1998 • 14,345 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

1984 • 884 citations

Cytotoxic T-cell memory without antigen

1994 • 669 citations

Immunology Taught by Viruses

1996 • 656 citations

Predominant Role for Directly Transfected Dendritic Cells in Antigen Presentation to CD8+ T Cells after Gene Gun Immunization

1998 • 569 citations

In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells

1997 • 560 citations

T Cell Deletion in High Antigen Dose Therapy of Autoimmune Encephalomyelitis

1994 • 530 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo.

1993 • 487 citations

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates

1991 • 460 citations

Virus-specific major MHC class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

1998 • 380 citations

Differentiation of Naive CTL to Effector and Memory CTL: Correlation of Effector Function with Phenotype and Cell Division

1998 • 379 citations

Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide.

1991 • 334 citations

Antigen Presentation by Dendritic Cells after Immunization with DNA Encoding a Major Histocompatibility Complex Class II–restricted Viral Epitope

1997 • 326 citations

Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen‐specific T cells

1993 • 276 citations

Primary stimulation by dendritic cells induces antiviral proliferative and cytotoxic T cell responses in vitro.

1989 • 260 citations

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

1996 • 259 citations

T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides

1993 • 256 citations

On the role of antigen in maintaining cytotoxic T-cell memory.

1996 • 237 citations

T cell priming versus T cell tolerance induced by synthetic peptides.

1995 • 230 citations

Induction of ovalbumin-specific cytotoxic T cells by in vivo peptide immunization.

1989 • 220 citations

Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide.

1990 • 199 citations

Dendritic Cells Efficiently Induce Protective Antiviral Immunity

1998 • 189 citations

Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection

1997 • 162 citations

Viral and Bacterial Infections Interfere with Peripheral Tolerance Induction and Activate CD8+ T Cells to Cause Immunopathology

1998 • 161 citations

Induction of immune responses in vivo with small numbers of veiled (dendritic) cells.

1983 • 149 citations

Activation of naive, memory and effector T cells

1994 • 141 citations

Enhancement of immune response to naked DNA vaccine by immunization with transfected dendritic cells

1997 • 135 citations

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without “memory T cells”?

1997 • 131 citations

Peptide Antigen Treatment of Naive and Virus-Immune Mice: Antigen-Specific Tolerance Versus Immunopathology

1997 • 126 citations

Anti‐viral protection and prevention of lymphocytic choriomeningitis or of the local footpad swelling reaction in mice by immunization with vaccinia‐recombinant virus expressing LCMV‐WE nucleoprotein or glycoprotein

1989 • 123 citations

Vaccination for Disease

1991 • 117 citations

A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro

1997 • 87 citations

Abolition of specific immune response defect by immunization with dendritic cells

1985 • 68 citations