Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic Lineages

1994 • 1,506 citations

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1994 • 1,412 citations

Oncogenic Transcription Factors in the Human Acute Leukemias

1997 • 1,227 citations

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities.

1996 • 1,115 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 729 citations

FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

1997 • 723 citations

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

1993 • 703 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 637 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

Oncoprotein Networks

1997 • 532 citations

Mechanism of active transcriptional repression by the retinoblastoma protein

1995 • 494 citations

Functional Synergy and Physical Interactions of the Erythroid Transcription Factor GATA-1 with the Krüppel Family Proteins Sp1 and EKLF

1995 • 475 citations

Spi-1 is a putative oncogene in virally induced murine erythroleukaemias

1988 • 470 citations

A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins.

1993 • 464 citations

PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors

1998 • 425 citations

Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.

1990 • 422 citations

Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

1991 • 404 citations

CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation

1998 • 357 citations

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

1993 • 317 citations

The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene.

1993 • 260 citations

Friend virus-induced erythroleukemia and the multistage nature of cancer

1991 • 249 citations

Multiple Functional Domains of AML1: PU.1 and C/EBPα Synergize with Different Regions of AML1

1998 • 218 citations

Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.

1993 • 218 citations

Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1

1993 • 211 citations

Induction of cyclin D1 by simian virus 40 small tumor antigen

1996 • 209 citations

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1.

1995 • 193 citations

Transcriptional activity of Pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila

1997 • 189 citations

Spi-1/PU.1 Transgenic Mice Develop Multistep Erythroleukemias

1996 • 187 citations

Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells

1996 • 180 citations

Induction of transformed cells to terminal differentiation and the modulation of gene expression.

1987 • 163 citations

Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1.

1992 • 160 citations

Role of PU.1 in Hematopoiesis

1998 • 159 citations

Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis.

1993 • 152 citations

The lineage commitment of haemopoietic progenitor cells

1997 • 148 citations

The putative oncogene Spi-1: murine chromosomal localization and transcriptional activation in murine acute erythroleukemias.

1989 • 140 citations

The Transcription Factor Spi-1/PU.1 Interacts with the Potential Splicing Factor TLS

1998 • 137 citations

Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: evidence that NF-E2 is essential for globin expression.

1994 • 135 citations

Ligand-Dependent Repression of the Erythroid Transcription Factor GATA-1 by the Estrogen Receptor

1995 • 132 citations

PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer.

1994 • 123 citations

Spi-1/PU.1: an oncogene of the Ets family

1994 • 115 citations

Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6 beta (C/EBP delta, CRP3).

1995 • 111 citations

In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.

1992 • 95 citations

The Transcription Factor Spi-1/PU.1 Binds RNA and Interferes with the RNA-binding Protein p54nrb

1996 • 94 citations

Deregulated expression of the PU.1 transcription factor blocks murine erythroleukemia cell terminal differentiation

1997 • 93 citations

Activation of Transcription by PU.1 Requires both Acidic and Glutamine Domains

1996 • 93 citations

The Ets-related transcription factor PU.1 immortalizes erythroblasts.

1993 • 92 citations

Expression of the chicken GATA factor family during early erythroid development and differentiation

1993 • 92 citations

Overexpression of PU.1 Induces Growth and Differentiation Inhibition and Apoptotic Cell Death in Murine Erythroleukemia Cells

1997 • 90 citations

trans-Activation of a Globin Promoter in Nonerythroid Cells

1991 • 84 citations

Role of the PU.1 transcription factor in controlling differentiation of Friend erythroleukemia cells.

1992 • 84 citations

Spi-1/PU.1 Is a Positive Regulator of the Fli-1 Gene Involved in Inhibition of Erythroid Differentiation in Friend Erythroleukemic Cell Lines

1999 • 75 citations

Functional interference between the Spi-1/PU.1 oncoprotein and steroid hormone or vitamin receptors.

1993 • 61 citations

A common site for immortalizing proviral integrations in Friend erythroleukemia: molecular cloning and characterization

1989 • 60 citations

The PU.1 transcription factor is the product of the putative oncogene Spi-1

1990 • 51 citations

Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1

1994 • 50 citations

Mouse β-Globin DNA-Binding Protein B1 is Identical to a Proto-Oncogene, the Transcription Factor Spi-1/PU.1, and is Restricted in Expression to Hematopoietic Cells and the Testis

1993 • 45 citations

The Ets-Related Transcription Factor PU.1 Immortalizes Erythroblasts

1993 • 41 citations

PU.1 negatively regulates the CD11c integrin gene promoter through recognition of the major transcriptional start site

1997 • 41 citations

trans-Activation of a globin promoter in nonerythroid cells.

1991 • 40 citations

Repression of I-Aβ Gene Expression by the Transcription Factor PU.1

1995 • 39 citations

Characterization of Spi-B, a Transcription Factor Related to the Putative Oncoprotein Spi-l/PU.l

1992 • 35 citations

Erythroid differentiation of mouse erythroleukemia cells results in reorganization of protein-DNA complexes in the mouse beta maj globin promoter but not its distal enhancer.

1993 • 32 citations

Role of the PU.1 Transcription Factor in Controlling Differentiation of Friend Erythroleukemia Cells

1992 • 31 citations

Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1

1993 • 26 citations

In Vivo Footprinting of the Human α-Globin Locus Upstream Regulatory Element by Guanine and Adenine Ligation-Mediated Polymerase Chain Reaction

1992 • 26 citations

Transcriptional Control of Hematopoiesis

1999 • 25 citations

Spi-1 and mutant p53 regulate different aspects of the proliferation and differentiation control of primary erythroid progenitors.

1995 • 19 citations

Spi-1/PU.1 Proto-oncogene Induces Opposite Effects on Monocytic and Erythroid Differentiation of K562 Cells

1998 • 19 citations

Erythroid Differentiation of Mouse Erythroleukemia Cells Results in Reorganization of Protein-DNA Complexes in the Mouse β^Maj Globin Promoter but not its Distal Enhancer

1993 • 8 citations

Regulatory Function of Delta/YY-1 on the Locus Control Region-like Sequence of Mouse Glycophorin Gene in Erythroleukemia Cells

1996 • 7 citations