Endothelial Progenitor Cells

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

1997 • 8,673 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Mechanisms of angiogenesis and arteriogenesis

2000 • 4,120 citations

Circulating Endothelial Progenitor Cells, Vascular Function, and Cardiovascular Risk

2003 • 3,381 citations

Bone Marrow Origin of Endothelial Progenitor Cells Responsible for Postnatal Vasculogenesis in Physiological and Pathological Neovascularization

1999 • 3,280 citations

Neovascularization of ischemic myocardium by human bone-marrow–derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function

2001 • 2,583 citations

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

1999 • 2,425 citations

Number and Migratory Activity of Circulating Endothelial Progenitor Cells Inversely Correlate With Risk Factors for Coronary Artery Disease

2001 • 2,344 citations

Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors

2000 • 2,286 citations

Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)

2002 • 2,231 citations

Repair of Infarcted Myocardium by Autologous Intracoronary Mononuclear Bone Marrow Cell Transplantation in Humans

2002 • 2,094 citations

Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells

2001 • 1,999 citations

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2001 • 1,874 citations

Transplantation ofex vivoexpanded endothelial progenitor cells for therapeutic neovascularization

2000 • 1,869 citations

VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

1999 • 1,852 citations

Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand

2002 • 1,755 citations

AC133, a Novel Marker for Human Hematopoietic Stem and Progenitor Cells

1997 • 1,755 citations

Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial

2002 • 1,724 citations

Evidence for Circulating Bone Marrow-Derived Endothelial Cells

1998 • 1,666 citations

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

2000 • 1,427 citations

Vascular Endothelial Growth Factor

2009 • 1,276 citations

Therapeutic Potential of Ex Vivo Expanded Endothelial Progenitor Cells for Myocardial Ischemia

2001 • 1,239 citations

Current Perspectives on Statins

2000 • 1,220 citations

Mobilization of Endothelial Progenitor Cells in Patients With Acute Myocardial Infarction

2001 • 1,202 citations

Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic Neovascularization

2003 • 1,147 citations

Origin of endothelial progenitors in human postnatal bone marrow

2002 • 1,121 citations

HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway

2001 • 1,108 citations

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

2002 • 1,066 citations

Increase in Circulating Endothelial Progenitor Cells by Statin Therapy in Patients With Stable Coronary Artery Disease

2001 • 1,016 citations

HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway

2001 • 994 citations

Implantation of Bone Marrow Mononuclear Cells Into Ischemic Myocardium Enhances Collateral Perfusion and Regional Function via Side Supply of Angioblasts, Angiogenic Ligands, and Cytokines

2001 • 969 citations

Statin Therapy Accelerates Reendothelialization

2002 • 924 citations

Transplanted cord blood–derived endothelial precursor cells augment postnatal neovascularization

2000 • 908 citations

Origin of endothelial progenitors in human postnatal bone marrow

2002 • 880 citations

Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo

2001 • 841 citations

Vascular Trauma Induces Rapid but Transient Mobilization of VEGFR2 ⁺ AC133 ⁺ Endothelial Precursor Cells

2001 • 802 citations

Microalbuminuria Reduction With Valsartan in Patients With Type 2 Diabetes Mellitus

2002 • 794 citations

Vascular Endothelial Growth Factor and Angiopoietin-1 Stimulate Postnatal Hematopoiesis by Recruitment of Vasculogenic and Hematopoietic Stem Cells

2001 • 692 citations

Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?

2002 • 685 citations

Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization

2002 • 682 citations

HMG-CoA reductase inhibitor mobilizes bone marrow–derived endothelial progenitor cells

2001 • 653 citations

The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development

1999 • 651 citations

The Chemokine Receptor CXCR-4 Is Expressed on CD34+Hematopoietic Progenitors and Leukemic Cells and Mediates Transendothelial Migration Induced by Stromal Cell-Derived Factor-1

1998 • 642 citations

Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment

2002 • 638 citations

Fundamentals of Endothelial Function for the Clinical Cardiologist

2002 • 608 citations

HMG-CoA reductase inhibitor mobilizes bone marrow–derived endothelial progenitor cells

2001 • 601 citations

Endothelial Progenitor Cell Vascular Endothelial Growth Factor Gene Transfer for Vascular Regeneration

2002 • 587 citations

Vascular Endothelial Growth Factor ₁₆₅ Gene Transfer Augments Circulating Endothelial Progenitor Cells in Human Subjects

2000 • 570 citations

Assessment of the Tissue Distribution of Transplanted Human Endothelial Progenitor Cells by Radioactive Labeling

2003 • 560 citations

Transdifferentiation of Blood-Derived Human Adult Endothelial Progenitor Cells Into Functionally Active Cardiomyocytes

2003 • 547 citations

Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice

2000 • 490 citations

Augmentation of Postnatal Neovascularization With Autologous Bone Marrow Transplantation

2001 • 467 citations

Bone Marrow–Derived Progenitor Cells Modulate Vascular Reendothelialization and Neointimal Formation

2002 • 434 citations

HMG-CoA Reductase Inhibitors Reduce Senescence and Increase Proliferation of Endothelial Progenitor Cells via Regulation of Cell Cycle Regulatory Genes

2003 • 390 citations

VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells

2002 • 377 citations

Promotion of Collateral Growth by Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Coronary Artery Disease

2001 • 334 citations

Constitutive Human Telomerase Reverse Transcriptase Expression Enhances Regenerative Properties of Endothelial Progenitor Cells

2002 • 300 citations

VEGF gene transfer mobilizes endothelial progenitor cells in patients with inoperable coronary disease

2000 • 287 citations

Enhanced endothelialization and microvessel formation in polyester grafts seeded with CD34+ bone marrow cells

2000 • 277 citations

Determination of bone marrow–derived endothelial progenitor cell significance in angiogenic growth factor–induced neovascularization in vivo

2002 • 272 citations

Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor 2(flk-1) Are Expressed during Vasculogenesis and Vascular Differentiation in the Quail Embryo

1995 • 270 citations

Akt Takes Center Stage in Angiogenesis Signaling

2000 • 264 citations

Coronary artery injury and the biology of atherosclerosis: inflammation, thrombosis, and stabilization

2000 • 221 citations

Improvement in Coronary Flow Reserve Determined by Positron Emission Tomography After 6 Months of Cholesterol-Lowering Therapy in Patients With Early Stages of Coronary Atherosclerosis

1999 • 202 citations

Vascular Progenitors From Biology to Treatment

2002 • 197 citations

Cloning and relative expression analysis of rat stromal cell derived factor-1 (SDF-1)1: SDF-1 alpha mRNA is selectively induced in rat model of myocardial infarction.

2001 • 180 citations

Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors

2002 • 179 citations

Contribution of marrow-derived progenitors to vascular and cardiac regeneration

2002 • 161 citations

Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Grant MB,∗∗Program in Stem Cell Biology, Department of Pharmacology and Therapeutics, University of Florida Shands Cancer Center, Gainesville, FL 32610-0232. E-mail: [email protected] May WS, Caballero S, Brown GAJ, Guthrie SM, Mames RN, Byrne BJ, Vaught T, Spoerri PE, Peck AB, Scott EW. Nat Med 2002;6:607-612.

2002 • 141 citations

The Chemokine Receptor CXCR-4 Is Expressed on CD34+Hematopoietic Progenitors and Leukemic Cells and Mediates Transendothelial Migration Induced by Stromal Cell-Derived Factor-1

1998 • 136 citations

VEGF increases engraftment of bone marrow-derived endothelial progenitor cells (EPCs) into vasculature of newborn murine recipients

2002 • 119 citations

Autologous Bone Marrow Implantation Induced Angiogenesis and Improved Deteriorated Exercise Capacity in a Rat Ischemic Hindlimb Model

2001 • 114 citations

Hematopoietic, vascular and cardiac fates of bone marrow-derived stem cells

2002 • 102 citations

Ecstasy danger hits the headlines

2002 • 101 citations

Expression and secretion of vascular endothelial growth factor-A by cytokine-stimulated hematopoietic progenitor cells

2000 • 96 citations

Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells

2002 • 87 citations

Endothelial Progenitor Cells: Regulation and Contribution to Adult Neovascularization

2002 • 81 citations

Autologous bone marrow cell implantation as therapeutic angiogenesis for ischemic hindlimb in diabetic rat model

2003 • 57 citations

Real-Time Three-Dimensional Echocardiography With Real-Time Volume Rendering in Assessment of Left Ventricular Apical Thrombi

2002 • 13 citations