Vascular Progenitors From Biology to Treatment

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

1997 • 8,673 citations

Bone marrow cells regenerate infarcted myocardium

2001 • 5,234 citations

Mechanisms of angiogenesis and arteriogenesis

2000 • 4,120 citations

Bone Marrow Origin of Endothelial Progenitor Cells Responsible for Postnatal Vasculogenesis in Physiological and Pathological Neovascularization

1999 • 3,280 citations

Neovascularization of ischemic myocardium by human bone-marrow–derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function

2001 • 2,583 citations

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

1999 • 2,425 citations

Number and Migratory Activity of Circulating Endothelial Progenitor Cells Inversely Correlate With Risk Factors for Coronary Artery Disease

2001 • 2,344 citations

Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors

2000 • 2,286 citations

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

1999 • 2,034 citations

Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells

2001 • 1,999 citations

Transplantation ofex vivoexpanded endothelial progenitor cells for therapeutic neovascularization

2000 • 1,869 citations

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

2001 • 1,640 citations

Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

1999 • 1,618 citations

Origins of circulating endothelial cells and endothelial outgrowth from blood

2000 • 1,529 citations

Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors

2000 • 1,372 citations

Therapeutic Potential of Ex Vivo Expanded Endothelial Progenitor Cells for Myocardial Ischemia

2001 • 1,239 citations

Role of vascular endothelial growth factor in regulation of physiological angiogenesis

2001 • 1,068 citations

The Evolving Concept of a Stem Cell

2001 • 1,058 citations

Notch signaling is essential for vascular morphogenesis in mice

2000 • 1,042 citations

Vascular Trauma Induces Rapid but Transient Mobilization of VEGFR2 ⁺ AC133 ⁺ Endothelial Precursor Cells

2001 • 802 citations

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

1999 • 790 citations

PDGF, TGF-β, and Heterotypic Cell–Cell Interactions Mediate Endothelial Cell–induced Recruitment of 10T1/2 Cells and Their Differentiation to a Smooth Muscle Fate

1998 • 789 citations

Vascular Endothelial Growth Factor and Angiopoietin-1 Stimulate Postnatal Hematopoiesis by Recruitment of Vasculogenic and Hematopoietic Stem Cells

2001 • 692 citations

The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain

2001 • 614 citations

Matrix Metalloproteinase 9 and Vascular Endothelial Growth Factor Are Essential for Osteoclast Recruitment into Developing Long Bones

2000 • 589 citations

Common Epicardial Origin of Coronary Vascular Smooth Muscle, Perivascular Fibroblasts, and Intermyocardial Fibroblasts in the Avian Heart

1998 • 535 citations

A Role for Hematopoietic Stem Cells in Promoting Angiogenesis

2000 • 512 citations

Host bone-marrow cells are a source of donor intimal smooth- muscle–like cells in murine aortic transplant arteriopathy

2001 • 498 citations

Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia

2001 • 498 citations

Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice

2000 • 490 citations

Vascular Endothelial Growth Factor Can Substitute for Macrophage Colony-Stimulating Factor in the Support of Osteoclastic Bone Resorption

1999 • 438 citations

Arteriovenous malformations in mice lacking activin receptor-like kinase-1

2000 • 438 citations

Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel® under angiogenic conditions

2001 • 418 citations

Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo

2001 • 400 citations

Ephrin-B2 Selectively Marks Arterial Vessels and Neovascularization Sites in the Adult, with Expression in Both Endothelial and Smooth-Muscle Cells

2001 • 362 citations

Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts

2000 • 345 citations

Expression of EphrinB2 Identifies a Stable Genetic Difference Between Arterial and Venous Vascular Smooth Muscle as Well as Endothelial Cells, and Marks Subsets of Microvessels at Sites of Adult Neovascularization

2001 • 308 citations

Origin of neointimal endothelium and α-actin–positive smooth muscle cells in transplant arteriosclerosis

2001 • 288 citations

VEGF gene transfer mobilizes endothelial progenitor cells in patients with inoperable coronary disease

2000 • 287 citations

ROLE OF CARDIAC NEURAL CREST CELLS IN CARDIOVASCULAR DEVELOPMENT

1998 • 276 citations

The role of FGF and VEGF in angioblast induction and migration during vascular development

2001 • 240 citations

Plasticity of endothelial cells during arterial-venous differentiation in the avian embryo

2001 • 235 citations

Smooth Muscle Cell Origin and Its Relation to Heterogeneity in Development and Disease

1999 • 231 citations

Eph receptors and ephrins: Regulators of guidance and assembly

2000 • 217 citations

A molecular analysis of matrix remodeling and angiogenesis during long bone development

2001 • 172 citations

CXCR-4 Desensitization Is Associated with Tissue Localization of Hemopoietic Progenitor Cells

2001 • 165 citations

Expression of smooth muscle alpha-actin in mesenchymal cells during formation of avian endocardial cushion tissue: A role for transforming growth factor β3

1997 • 141 citations

Multipotential Cells in the Bone Marrow Stroma: Regulation in the Context of Organ Physiology

1999 • 127 citations

Immunolocalisation of vascular endothelial growth factor (VEGF) in human neonatal growth plate cartilage

1999 • 126 citations

Autologous Bone Marrow Implantation Induced Angiogenesis and Improved Deteriorated Exercise Capacity in a Rat Ischemic Hindlimb Model

2001 • 114 citations

Stromal Derived Factor-1–Induced Chemokinesis of Cord Blood CD34+ Cells (Long-Term Culture-Initiating Cells) Through Endothelial Cells Is Mediated by E-Selectin

1999 • 107 citations

Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos

2000 • 107 citations

Erythroblasts are a source of angiogenic factors

2001 • 105 citations

Expression and secretion of vascular endothelial growth factor-A by cytokine-stimulated hematopoietic progenitor cells

2000 • 96 citations

Neuropilin-1 expression in osteogenic cells: Down-regulation during differentiation of osteoblasts into osteocytes

2001 • 79 citations

Bmx Tyrosine Kinase Is Specifically Expressed in the Endocardium and the Endothelium of Large Arteries

1997 • 77 citations

Neuropilin-1 Is Expressed on Bone Marrow Stromal Cells: A Novel Interaction With Hematopoietic Cells?

1999 • 73 citations

The role of metalloproteinases and adhesion molecules in interleukin-8-induced stem-cell mobilization

2000 • 67 citations

Building the vertebrate vasculature: research is going swimmingly

2000 • 62 citations

Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model

2000 • 62 citations

Basic Concepts of (Myocardial) Angiogenesis: Role of Vascular Endothelial Growth Factor and Angiopoietin.

1999 • 37 citations