The c-kit Molecule and the Surface Immunophenotype of Human Acute Leukemia

Proposed Revised Criteria for the Classification of Acute Myeloid Leukemia

1985 • 2,981 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells.

1984 • 1,193 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1990 • 632 citations

Lineage promiscuity in hemopoietic differentiation and leukemia

1986 • 572 citations

Differentiation-Linked Leukemogenesis in Lymphocytes

1986 • 359 citations

Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development.

1991 • 346 citations

Acute mixed lineage leukemia: clinicopathologic correlations and prognostic significance

1985 • 310 citations

Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells

1991 • 277 citations

Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells

1991 • 202 citations

Monoclonal antibody YB5.B8 identifies the human c-kit protein product

1991 • 160 citations

The expression of the proto-oncogene C-kit in the blast cells of acute myeloblastic leukemia.

1989 • 157 citations

HYBRID ACUTE LEUKAEMIA

1987 • 157 citations

Acute myeloid leukemia with T-lymphoid features: a distinct biologic and clinical entity

1988 • 155 citations

Blasts from patients with acute myelogenous leukemia express functional receptors for stem cell factor

1992 • 113 citations

Isolation and characterization of a monoclonal antibody that recognizes the human c-kit receptor

1992 • 111 citations

CD 7 positive acute myeloid leukaemia: a subtype associated with cell immaturity

1989 • 105 citations

The product of the proto-oncogene c-kit (P145c-kit) is a human bone marrow surface antigen of hemopoietic precursor cells which is expressed on a subset of acute non-lymphoblastic leukemic cells.

1991 • 98 citations

Mast cell growth factor, a ligand for the receptor encoded by c-kit, affects the growth in culture of the blast cells of acute myeloblastic leukemia.

1991 • 73 citations

The hemopoietic stem cell antigen, CD34, is encoded by a gene located on chromosome 1.

1989 • 69 citations

Mixed-lineage leukemia revisited: acute lymphocytic leukemia with myeloperoxidase-positive blasts by electron microscopy [see comments]

1990 • 65 citations

CD7+ acute non-lymphocytic leukemia: Evidence for an early multipotential progenitor

1990 • 56 citations

Growth of clonogenic myeloblastic leukemic cells in the presence of human recombinant erythropoietin in addition to various human recombinant hematopoietic growth factors

1988 • 49 citations

Granulocyte colony-stimulating factor receptors on human acute leukemia: biphenotypic leukemic cells possess granulocyte colony-stimulating factor receptors.

1992 • 42 citations

c-kit gene expression in CD7-positive acute lymphoblastic leukemia: close correlation with expression of myeloid-associated antigen CD13.

1992 • 42 citations

Single-cell immunofluorescence assay for terminal transferase: human leukaemic and non-leukaemic cells

1980 • 35 citations

Effect of human recombinant granulocyte/macrophage colony-stimulating factor and native granulocyte colony-stimulating factor on clonogenic leukemic blast cells.

1987 • 31 citations