Death-Associated Protein Kinase-Related Protein 1, a Novel Serine/Threonine Kinase Involved in Apoptosis

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1997 • 5,665 citations

Regulation of Cell Death Protease Caspase-9 by Phosphorylation

1998 • 3,129 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

1997 • 2,245 citations

Life, death, and the pursuit of apoptosis.

1996 • 1,333 citations

[2] Protein kinase catalytic domain sequence database: Identification of conserved features of primary structure and classification of family members

1991 • 1,225 citations

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

1998 • 1,062 citations

RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1995 • 964 citations

The central executioners of apoptosis: caspases or mitochondria?

1998 • 772 citations

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.

1995 • 574 citations

Inhibition of Ced-3/ICE-related Proteases Does Not Prevent Cell Death Induced by Oncogenes, DNA Damage, or the Bcl-2 Homologue Bak

1997 • 555 citations

The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases

1997 • 507 citations

RIP2 Is a Novel NF-κB-activating and Cell Death-inducing Kinase

1998 • 425 citations

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

1997 • 408 citations

Bcl-2 Undergoes Phosphorylation by c-Jun N-terminal Kinase/Stress-activated Protein Kinases in the Presence of the Constitutively Active GTP-binding Protein Rac1

1997 • 406 citations

DAP kinase links the control of apoptosis to metastasis

1997 • 394 citations

Dap-Kinase Participates in TNF-α–And FAS-Induced Apoptosis and Its Function Requires the Death Domain

1999 • 272 citations

ZIP Kinase, a Novel Serine/Threonine Kinase Which Mediates Apoptosis

1998 • 225 citations

RIP3, a Novel Apoptosis-inducing Kinase

1999 • 222 citations

Stress signals for apoptosis: ceramide and c-Jun kinase

1998 • 211 citations

DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene

1997 • 207 citations

DRAKs, Novel Serine/Threonine Kinases Related to Death-associated Protein Kinase That Trigger Apoptosis

1998 • 197 citations

A Genetic Tool Used to Identify Thioredoxin as a Mediator of a Growth Inhibitory Signal

1991 • 189 citations

Kinase cascades regulating entry into apoptosis

1997 • 157 citations

Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation.

1989 • 141 citations

Activation of c-Jun N-terminal Kinase Antagonizes an Anti-apoptotic Action of Bcl-2

1997 • 132 citations

Death associated proteins (DAPs): from gene identification to the analysis of their apoptotic and tumor suppressive functions

1998 • 130 citations

Identification of RIP3, a RIP-like kinase that activates apoptosis and NFκB

1999 • 129 citations

Cloning and characterization of Dlk, a novel serine/threonine kinase that is tightly associated with chromatin and phosphorylates core histones

1998 • 114 citations

Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha - and Fas-induced cell death

1999 • 108 citations

The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis

1998 • 91 citations

Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction?

1998 • 58 citations

DAP genes: novel apoptotic genes isolated by a functional approach to gene cloning

1998 • 43 citations

Death-associated proteins: from gene identification to the analysis of their apoptotic and tumour suppressive functions

1998 • 23 citations