Mice deficient for the glycoprotein show subtle abnormalities in myelin

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Developments of a water-maze procedure for studying spatial learning in the rat

1984 • 6,896 citations

Place navigation impaired in rats with hippocampal lesions

1982 • 6,277 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1992 • 1,632 citations

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 • 1,531 citations

Electrodiagnosis in Diseases of Nerve and Muscle: Principles and Practice

1983 • 1,485 citations

Polyacrylamide Gel Electrophoresis of Viral Proteins

1971 • 1,477 citations

MYELINATION IN RAT BRAIN: METHOD OF MYELIN ISOLATION¹

1973 • 1,412 citations

An improved culture medium supports development of random-bred 1-cell mouse embryos in vitro

1989 • 1,119 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1987 • 811 citations

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion.

1984 • 739 citations

Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1

1984 • 723 citations

Electrodiagnosis in diseases of nerve and muscle: principles and practice

1990 • 657 citations

Inhibitors of Neurite Growth

1993 • 545 citations

Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons

1992 • 493 citations

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve.

1986 • 482 citations

Peripheral Neuropathy

1994 • 471 citations

Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1

1983 • 431 citations

Expression and functional roles of neural cell surface molecules and extracellular matrix components during development and regeneration of peripheral nerves

1994 • 411 citations

J1/tenascin is a repulsive substrate for central nervous system neurons

1990 • 380 citations

The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamily

1987 • 370 citations

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve.

1988 • 364 citations

Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter

1987 • 361 citations

Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction.

1987 • 335 citations

Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing.

1987 • 320 citations

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

1991 • 296 citations

Molecular cloning and primary structure of myelin-associated glycoprotein.

1987 • 284 citations

The myelin-associated glycoprotein is enriched in multivesicular bodies and periaxonal membranes of actively myelinating oligodendrocytes.

1989 • 241 citations

Immunohistological localization of the adhesion molecules L1, N‐CAM, and MAG in the developing and adult optic nerve of mice

1989 • 233 citations

Isolation and nucleotide sequence of mouse NCAM cDNA that codes for a Mr 79,000 polypeptide without a membrane-spanning region.

1987 • 231 citations

Compact myelin exists in the absence of basic protein in the shiverer mutant mouse

1980 • 224 citations

Genomic DNA microextraction: A method to screen numerous samples

1992 • 221 citations

Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing.

1986 • 219 citations

Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene

1992 • 212 citations

Presence of the myelin-associated glycoprotein correlates with alterations in the periodicity of peripheral myelin.

1982 • 207 citations

A STRUCTURAL ANALYSIS OF THE MYELIN SHEATH IN THE CENTRAL NERVOUS SYSTEM

1967 • 177 citations

Myelin‐Associated Glycoprotein Location and Potential Functions^a

1990 • 167 citations

Enhanced expression of the extracellular matrix molecule J1/tenascin in the regenerating adult mouse sciatic nerve

1990 • 162 citations

Biosynthesis and membrane topography of the neural cell adhesion molecule L1.

1985 • 157 citations

THE ROLE OF MACROPHAGES AND EICOSANOIDS IN THE PATHOGENESIS OF EXPERIMENTAL ALLERGIC NEURITIS

1988 • 152 citations

Recombinant peripheral myelin protein P_o confers both adhesion and neurite outgrowth‐promoting properties

1990 • 133 citations

Expression of janusin (J1–160/180) in the retina and optic nerve of the developing and adult mouse

1993 • 125 citations

Progress in the molecular understanding of hereditary peripheral neuropathies reveals new insights into the biology of the peripheral nervous system

1993 • 122 citations

Morphometric Analysis of Normal, Mutant, and Transgenic CNS: Correlation of Myelin Basic Protein Expression to Myelinogenesis

1992 • 111 citations

Localization of Janusin mRNA in the Central Nervous System of the Developing and Adult Mouse

1993 • 106 citations

The L2/HNK‐1 Carbohydrate Mediates Adhesion of Neural Cells to Laminin

1993 • 105 citations

Evidence for an early role for myelin‐associated glycoprotein in the process of myelination

1989 • 103 citations

Schwann cells infected with a recombinant retrovirus expressing myelin-associated glycoprotein antisense RNA do not form myelin

1991 • 98 citations

L2/HNK‐1 carbohydrate and protein‐protein interactions mediate the homophilic binding of the neural adhesion molecule P0

1992 • 98 citations

Conduction failure and nerve conduction slowing in experimental allergic neuritis induced by P₂‐specific T‐cell lines

1986 • 98 citations

Myelin-associated glycoprotein: A developmental change

1973 • 93 citations

Immunocytological localization of the major peripheral nervous system glycoprotein P0 and the L2/HNK-1 and L3 carbohydrate structures in developing and adult mouse sciatic nerve

1988 • 87 citations

Characterization of binding properties of the myelin-associated glycoprotein to extracellular matrix constituents.

1987 • 83 citations

Differential splicing of MAG transcripts during CNS and PNS development

1988 • 83 citations

Peripheral myelin in the mouse mutant Shiverer

1980 • 82 citations

Phylogeny of Myelin Proteins

1990 • 82 citations

Binding properties of liposomes containing the myelin‐associated glycoprotein MAG to neural cell cultures

1990 • 80 citations

Molecular specificity of L2 monoclonal antibodies that bind to carbohydrate determinants of neural cell adhesion molecules and their resemblance to other monoclonal antibodies recognizing the myelin-associated glycoprotein

1986 • 80 citations

A new computer program for detailed off-line analysis of swimming navigation in the Morris water maze

1992 • 75 citations

The novel carbohydrate epitope L3 is shared by some neural cell adhesion molecules.

1987 • 74 citations

Interactions of the neural cell adhesion molecule and the myelin-associated glycoprotein with collagen type I: involvement in fibrillogenesis.

1992 • 66 citations

The myelin-associated glycoprotein gene: Mapping to human chromosome 19 and mouse chromosome 7 and expression in quivering mice

1987 • 64 citations

Down-regulation of myelin-associated glycoprotein on Schwann cells by interferon-γ and tumor necrosis factor-α affects neurite outgrowth

1991 • 60 citations

Adaptation of a non-radioactive in situ hybridization method to electron microscopy: detection of tenascin mRNAs in mouse cerebellum with digoxigenin-labelled probes and gold-labelled antibodies

1993 • 58 citations

Abnormal Expression of the Myelin‐Associated Glycoprotein in the Central Nervous System of Dysmyelinating Mutant Mice

1985 • 57 citations

Complex expression pattern of tenascin during innervation of the posterior limb buds of the developing chicken

1991 • 50 citations

A Survey of Neurological Mutant Mice. pp 99–109

1988 • 46 citations

Expression of the large myelin-associated glycoprotein isoform during the development in the mouse peripheral nervous system

1991 • 40 citations

A Survey of Neurological Mutant Mice

1988 • 38 citations

A sensitive method for the detection and quantification of conduction deficits in nerve

1980 • 36 citations

Developmental Expression of the Myelin‐Associated Glycoprotein in the Peripheral Nervous System Is Different from That in the Central Nervous System

1985 • 32 citations

Hypomyelination in the peripheral nervous system of shiverer mice and in Shiverer ↔ Normal chimaera

1984 • 31 citations

Chromosomal Location of the Mouse Gene that Encodes the Myelin‐Associated Glycoproteins

1988 • 28 citations

Structure of mouse myelin-associated glycoprotein gene

1991 • 25 citations

Myelin‐Associated Glycoprotein in the Central and Peripheral Nervous System of Quaking Mice

1987 • 22 citations

Expression of myelin protein genes in quaking mouse brain

1988 • 21 citations

Functional Topography of the Myelin‐associated Glycoprotein. I. Mapping of Domains by Electron Microscopy

1993 • 19 citations

In situ freezing of embryonic stem cells in multiwell plates

1991 • 18 citations

Impaired acquisition of swimming navigation in adult mice exposed prenatally to oxazepam

1993 • 16 citations

Myelin‐associated glycoprotein is not detectable in perikaryal myelin of spiral ganglion neurons of adult mice

1994 • 15 citations