Control of Fibroblast Growth Factor Receptor Kinase Signal Transduction by Heterodimerization of Combinatorial Splice Variants

Antibodies, a laboratory manual

1989 • 12,929 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Oncogenes and signal transduction

1991 • 2,816 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures.

1987 • 1,703 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1986 • 1,100 citations

Studies of Inositol Phospholipid-Specific Phospholipase C

1989 • 914 citations

A one-step purification of membrane proteins using a high efficiency immunomatrix.

1982 • 782 citations

Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction

1992 • 625 citations

Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

1987 • 624 citations

Binding of SH2 Domains of Phospholipase Cγ1, GAP, and Src to Activated Growth Factor Receptors

1990 • 608 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

1991 • 585 citations

FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.

1991 • 541 citations

An Essential Heparin-Binding Domain in the Fibroblast Growth Factor Receptor Kinase

1993 • 520 citations

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

1987 • 508 citations

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.

1991 • 443 citations

Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis

1992 • 438 citations

Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis

1992 • 414 citations

Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy.

1993 • 408 citations

The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain.

1991 • 406 citations

Dimerization of B-type Platelet-derived Growth Factor Receptors Occurs After Ligand Binding and Is Closely Associated with Receptor Kinase Activation

1989 • 366 citations

Diverse forms of a receptor for acidic and basic fibroblast growth factors.

1990 • 352 citations

Transcriptional regulation by dimerization: Two sides to an incestuous relationship

1990 • 343 citations

The Dominant W ⁴² Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase

1990 • 287 citations

A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor.

1992 • 272 citations

Inositol phospholipid-specific phospholipase C: interaction of the γ isoform with tyrosine kinase

1991 • 233 citations

A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerization.

1991 • 227 citations

Fibroblast Growth Factor Receptors from Liver Vary in Three Structural Domains

1991 • 227 citations

Heparin-binding growth factor type 1 (acidic fibroblast growth factor): a potential biphasic autocrine and paracrine regulator of hepatocyte regeneration.

1989 • 210 citations

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.

1991 • 198 citations

Evidence that autophosphorylation of solubilized receptors for epidermal growth factor is mediated by intermolecular cross-phosphorylation.

1989 • 193 citations

Ligand-induced transphosphorylation between different FGF receptors.

1991 • 189 citations

Inhibition of PDGF β Receptor Signal Transduction by Coexpression of a Truncated Receptor

1991 • 173 citations

Dimerization of mammalian progesterone receptors occurs in the absence of DNA and is related to the release of the 90-kDa heat shock protein.

1991 • 133 citations

Heparin-binding growth factor gene expression and receptor characteristics in normal rat prostate and two transplantable rat prostate tumors.

1989 • 127 citations

High and low affinity binding of heparin-binding growth factor to a 130-kDa receptor correlates with stimulation and inhibition of growth of a differentiated human hepatoma cell.

1988 • 126 citations

Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors.

1991 • 103 citations

Multiple mRNAs code for proteins related to the BEK fibroblast growth factor receptor.

1991 • 101 citations

Diverse Forms of a Receptor for Acidic and Basic Fibroblast Growth Factors

1990 • 100 citations

Transmembrane signaling by the human insulin receptor kinase. Relationship between intramolecular beta subunit trans- and cis-autophosphorylation and substrate kinase activation.

1992 • 98 citations

A Tyrosine-Phosphorylated Carboxy-Terminal Peptide of the Fibroblast Growth Factor Receptor (Flg) Is a Binding Site for the SH2 Domain of Phospholipase C-γ1

1991 • 93 citations

Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms.

1992 • 92 citations

Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation.

1988 • 82 citations

Expression and transforming activity of a variant of the heparin-binding fibroblast growth factor receptor (flg) gene resulting from splicing of the alpha exon at an alternate 3′-acceptor site

1992 • 49 citations

Identification and assay of fibroblast growth factor receptors

1991 • 47 citations

Identification of tyrosines 154 and 307 in the extracellular domain and 653 and 766 in the intracellular domain as phosphorylation sites in the heparin‐binding fibroblast growth factor receptor tyrosine kinase (flg)

1993 • 41 citations

Autophosphorylation within insulin receptor .beta.-subunits can occur as an intramolecular process

1991 • 32 citations

A Dominant Negative Mutation Suppresses the Function of Normal Epidermal Growth Factor Receptors by Heterodimerization

1991 • 31 citations

Receptor phenotype underlies differential response of hepatocytes and nonparenchymal cells to heparin-binding fibroblast growth factor type 1 (aFGF) and type 2 (bFGF)

1992 • 26 citations

Elution and Internal Amino Acid Sequencing of PVDF-Blotted Proteins

1992 • 23 citations

Dimers Direct Development

1991 • 15 citations