Oxidative damage to mitochondrial DNA and its relationship to diabetic complications

Role of Oxidative Stress in Development of Complications in Diabetes

1991 • 3,774 citations

Oxidative Stress and Diabetic Vascular Complications

1996 • 1,947 citations

Isolation of High‐Molecular‐Weight DNA from Mammalian Cells

1973 • 1,723 citations

Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

1988 • 1,709 citations

Mitochondrial control of nuclear apoptosis.

1996 • 1,363 citations

The biochemistry of programmed cell death

1995 • 997 citations

Protein glycation and oxidative stress in diabetes mellitus and ageing

1991 • 882 citations

Oxidative damage to DNA in diabetes mellitus

1996 • 789 citations

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

1987 • 778 citations

Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase.

1996 • 381 citations

Oxidative damage to mitochondrial DNA and its relationship to ageing

1995 • 350 citations

High glucose induces DNA damage in cultured human endothelial cells.

1986 • 244 citations

Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondrial DNA of human diaphragm

1991 • 203 citations

DNA damage in the kidneys of diabetic rats exhibiting microalbuminuria

1994 • 120 citations

The syndrome of diabetic amyotrophy

1977 • 101 citations

Oxygen Stress Induces an Apoptotic Cell Death Associated with Fragmentation of Mitochondrial Genome

1995 • 98 citations

Lipid peroxidation and mtDNA degeneration. A hypothesis

1992 • 66 citations

Oxidative damage to DNA

1995 • 58 citations

Subacute proximal diabetic neuropathy

1976 • 52 citations

Measurement of 8-OHdG in DNA by HPLC/ECD: The Importance of DNA Purity

1996 • 37 citations

Abnormalities in the Mitochondrial Permeability Transition in Diabetic Rats

1996 • 25 citations

Defective pattern of mitochondrial respiratory enzymes in mitochondrial myopathy

1989 • 23 citations

Quantification of mitochondrial DNA in heteroplasmic fibroblasts with competitive PCR.

1994 • 9 citations