Ca²⁺/Calmodulin-Dependent Protein Kinase II Is a Modulator of CARMA1-Mediated NF-κB Activation

Calcium's Role in Mechanotransduction during Muscle Development

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The Protein Kinase Complement of the Human Genome

2002 • 7,708 citations

A gene atlas of the mouse and human protein-encoding transcriptomes

2004 • 3,443 citations

A Gene-Coexpression Network for Global Discovery of Conserved Genetic Modules

2003 • 2,220 citations

Scansite 2.0: proteome-wide prediction of cell signaling interactions using short sequence motifs

2003 • 1,587 citations

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1997 • 1,533 citations

Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma

2000 • 978 citations

Isolation of phosphoproteins by immobilized metal (Fe3+) affinity chromatography

1986 • 773 citations

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity.

1994 • 718 citations

The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes

2004 • 674 citations

NF-κB functions in synaptic signaling and behavior

2003 • 672 citations

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling

2000 • 657 citations

Neuronal Ca²⁺/Calmodulin-Dependent Protein Kinase II: The Role of Structure and Autoregulation in Cellular Function

2002 • 634 citations

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics

2003 • 555 citations

Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

2001 • 551 citations

RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis.

1996 • 540 citations

Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

2003 • 524 citations

The newly synthesized selective Ca2+calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells

1991 • 497 citations

A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer

2003 • 421 citations

Bcl10 and MALT1, Independent Targets of Chromosomal Translocation in MALT Lymphoma, Cooperate in a Novel NF-κB Signaling Pathway

2001 • 409 citations

Functional Anatomy of a dsRNA Trigger

2000 • 397 citations

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation

2004 • 378 citations

Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

2003 • 375 citations

Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase

2003 • 366 citations

CARMA1 is a critical lipid raft–associated regulator of TCR-induced NF-κB activation

2002 • 338 citations

Phosphorylation of the CARMA1 Linker Controls NF-κB Activation

2005 • 333 citations

CARD11 and CARD14 Are Novel Caspase Recruitment Domain (CARD)/Membrane-associated Guanylate Kinase (MAGUK) Family Members that Interact with BCL10 and Activate NF-κB

2001 • 328 citations

The MAGUK Family Protein CARD11 Is Essential for Lymphocyte Activation

2003 • 326 citations

The mouse kinome: Discovery and comparative genomics of all mouse protein kinases

2004 • 299 citations

Identifying the MAGUK Protein Carma-1 as a Central Regulator of Humoral Immune Responses and Atopy by Genome-Wide Mouse Mutagenesis

2003 • 293 citations

A requirement for CARMA1 in TCR-induced NF-κB activation

2002 • 288 citations

Phosphorylation of CARMA1 Plays a Critical Role in T Cell Receptor-Mediated NF-κB Activation

2005 • 282 citations

Requirement for CARMA1 in Antigen Receptor-Induced NF-κB Activation and Lymphocyte Proliferation

2003 • 253 citations

PDK1 Nucleates T Cell Receptor-Induced Signaling Complex for NF-κB Activation

2005 • 249 citations

Small Interfering RNA-Mediated Gene Silencing in T Lymphocytes

2002 • 221 citations

CD3/CD28 Costimulation-Induced NF-κB Activation Is Mediated by Recruitment of Protein Kinase C-θ, Bcl10, and IκB Kinase β to the Immunological Synapse through CARMA1

2003 • 216 citations

Organization and evolution of multifunctional Ca2+/CaM-dependent protein kinase genes

2003 • 214 citations

CARD11 mediates factor-specific activation of NF-κB by the T cell receptor complex

2002 • 206 citations

Mice Lacking the CARD of CARMA1 Exhibit Defective B Lymphocyte Development and Impaired Proliferation of Their B and T Lymphocytes

2003 • 149 citations

Constitutive NF-κB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity

2005 • 135 citations

MALT1/Paracaspase Is a Signaling Component Downstream of CARMA1 and Mediates T Cell Receptor-induced NF-κB Activation

2004 • 120 citations

lnterleukin-2 transcriptional block by multifunctional Ca2+/ calmodulin kinase

1994 • 115 citations

Calmodulin-dependent Kinase II Mediates T Cell Receptor/CD3- and Phorbol Ester-induced Activation of IκB Kinase

2001 • 105 citations

Deciphering the pathway from the TCR to NF-κB

2006 • 94 citations

The Molecular Adapter Carma1 Controls Entry of IκB Kinase into the Central Immune Synapse

2004 • 85 citations

Ca2+/Calmodulin-dependent Protein Kinase IV Stimulates Nuclear Factor-κB Transactivation via Phosphorylation of the p65 Subunit

2001 • 83 citations

A Role for CaMKII in T Cell Memory

2000 • 74 citations

Calcium/Calmodulin-dependent Protein Kinase II (CaMKII) Localization Acts in Concert with Substrate Targeting to Create Spatial Restriction for Phosphorylation

2004 • 71 citations

Interaction of the CD5 cytoplasmic domain with the Ca2+ /calmodulin-dependent kinase IIδ

1998 • 46 citations

TCR Engagement Induces Proline-Rich Tyrosine Kinase-2 (Pyk2) Translocation to the T Cell-APC Interface Independently of Pyk2 Activity and in an Immunoreceptor Tyrosine-Based Activation Motif-Mediated Fashion

2002 • 43 citations

Genetic dissection of antigen receptor induced-NF-?B activation

2004 • 43 citations

Calcium/calmodulin-dependent protein kinase II is phosphorylated by protein kinase C in vitro

1993 • 38 citations

Homer-3 regulates activation of serum response element in T cells via its EVH1 domain

2003 • 34 citations