Vaccination of Seronegative Volunteers with a Human Immunodeficiency Virus Type 1env/revDNA Vaccine Induces Antigen‐Specific Proliferation and Lymphocyte Production of β‐Chemokines

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Vigorous HIV-1-Specific CD4 ⁺ T Cell Responses Associated with Control of Viremia

1997 • 1,868 citations

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

CD8 ⁺ Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication

1986 • 1,010 citations

Induction of Antigen-Specific Cytotoxic T Lymphocytes in Humans by a Malaria DNA Vaccine

1998 • 844 citations

The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

1998 • 666 citations

First Human Trial of a DNA-Based Vaccine for Treatment of Human Immunodeficiency Virus Type 1 Infection: Safety and Host Response

1998 • 637 citations

Toward an Understanding of the Correlates of Protective Immunity to HIV Infection

1996 • 421 citations

Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients

1998 • 409 citations

Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination

1997 • 314 citations

CD8+ cell anti-HIV activity correlates with the clinical state of the infected individual.

1991 • 279 citations

DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans.

1995 • 266 citations

Progress in the Development of an HIV-1 Vaccine

1998 • 262 citations

Simian immunodeficiency virus DNA vaccine trial in macaques

1996 • 240 citations

Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers

1997 • 234 citations

Immunization of non-human primates with DNA vaccines

1997 • 223 citations

HIV-1 Coreceptor Activity of CCR5 and Its Inhibition by Chemokines: Independence from G Protein Signaling and Importance of Coreceptor Downmodulation

1997 • 214 citations

T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses

1988 • 205 citations

Enhanced immunity to human immunodeficiency virus (HIV) envelope elicited by a combined vaccine regimen consisting of priming with a vaccinia recombinant expressing HIV envelope and boosting with gp160 protein.

1993 • 196 citations

Modulating the immune response to genetic immunization

1998 • 177 citations

Systemic immunological effects of cytokine genes injected into skeletal muscle.

1993 • 174 citations

Towards a DNA vaccine against tuberculosis

1994 • 122 citations

Why do we not have an HIV vaccine and how can we make one?

1998 • 112 citations

Induction of Humoral and Cellular Immune Responses to the Human Immunodeficiency Type 1 Virus in Nonhuman Primates by in Vivo DNA Inoculation

1995 • 109 citations

Direct transfection of viral and plasmid DNA into the liver or spleen of mice.

1984 • 107 citations

β-Chemokines and neutralizing antibody titers correlate with sterilizing immunity generated in HIV-1 vaccinated macaques

1998 • 93 citations

Enhancement of Cellular Immune Response in HIV-1 Seropositive Individuals: A DNA-Based Trial

1999 • 87 citations

Gene gun‐based nucleic acid immunization alone or in combination with recombinant vaccinia vectors suppresses virus burden in rhesus macaques challenged with a heterologous SIV

1997 • 72 citations

Simian Immunodeficiency Virus DNA Vaccine Trial in Macaques

1995 • 19 citations

Systemic immunological effects of cytokine genes injected into skeletal muscle.

1993 • 6 citations

Induction of a TH1 type cellular immune response to the human immunodeficiency type 1 virus by in vivo DNA inoculation.

1998 • 6 citations