Antigenic properties and population stability of a foot-and-mouth disease virus with an altered Arg-Gly-Asp receptor-recognition motif

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The three-dimensional structure of foot-and-mouth disease virus at 2.9 Å resolution

1989 • 854 citations

Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence

1982 • 826 citations

Developments in Biological Standardization

1993 • 617 citations

The evolutionary biology of viruses

1994 • 440 citations

The Cell Attachment Site on Foot-and-Mouth Disease Virus Includes the Amino Acid Sequence RGD (Arginine-Glycine-Aspartic Acid)

1989 • 389 citations

Efficient infection of cells in culture by type O foot-and-mouth disease virus requires binding to cell surface heparan sulfate

1996 • 370 citations

Location and Characterization of the Antigenic Portion of the FMDV Immunizing Protein

1982 • 365 citations

Antibodies against a preselected peptide recognize and neutralize foot and mouth disease virus.

1982 • 364 citations

Structure of a major immunogenic site on foot-and-mouth disease virus

1993 • 361 citations

Foot-And-Mouth Disease

1968 • 338 citations

Antibodies to the vitronectin receptor (integrin alpha V beta 3) inhibit binding and infection of foot-and-mouth disease virus to cultured cells

1995 • 303 citations

Tissue culture adaptation of foot-and-mouth disease virus selects viruses that bind to heparin and are attenuated in cattle

1997 • 292 citations

Antibody recognition of picornaviruses and escape from neutralization: a structural view

1995 • 279 citations

Exponential increases of RNA virus fitness during large population transmissions.

1995 • 278 citations

Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture

1983 • 269 citations

RGD sequence of foot-and-mouth disease virus isessential for infecting cells via the natural receptor but can be bypassed by anantibody-dependent enhancement pathway.

1994 • 258 citations

The structure and antigenicity of a type C foot-and-mouth disease virus

1994 • 258 citations

A large-scale evaluation of peptide vaccines against foot-and-mouth disease: lack of solid protection in cattle and isolation of escape mutants

1997 • 228 citations

Genetic Lesions Associated with Muller's Ratchet in an RNA Virus

1996 • 223 citations

Foot-and-Mouth Disease Virus Virulent for Cattle Utilizes the Integrin α _v β ₃ as Its Receptor

1998 • 216 citations

Nucleotide sequence heterogeneity of the RNA from a natural population of foot-and-mouth-disease virus

1980 • 203 citations

A single amino acid substitution affects multiple overlapping epitopes in the major antigenic site of foot-and-mouth disease virus of serotype C

1990 • 196 citations

Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction.

1995 • 194 citations

Chemical basis of antigenic variation in foot-and-mouth disease virus

1983 • 183 citations

Rapid selection of genetic and antigenic variants of foot-and-mouth disease virus during persistence in cattle

1988 • 178 citations

Multiple Virulence Determinants of Foot-and-Mouth Disease Virus in Cell Culture

1998 • 157 citations

Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller’s ratchet 1 1Edited by J. Karn

1999 • 153 citations

Genetic Variability and Antigenic Diversity of Foot-and-Mouth Disease Virus

1990 • 152 citations

Arginine-glycine-aspartic acid-specific binding by foot-and-mouth disease viruses to the purified integrin alpha(v)beta3 in vitro

1997 • 150 citations

Coevolution of cells and viruses in a persistent infection of foot-and-mouth disease virus in cell culture

1988 • 142 citations

Persistent infection of African buffalo (Syncerus caffer) with SAT-type foot-and-mouth disease viruses: rate of fixation of mutations, antigenic change and interspecies transmission

1996 • 138 citations

Foot-and-Mouth Disease Virus Populations Are Quasispecies

1992 • 133 citations

Subtyping of foot-and-mouth disease virus.

1976 • 130 citations

Evolution subverting essentiality: Dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus

1997 • 129 citations

Establishment of cell lines persistently infected with foot-and-mouth disease virus

1985 • 126 citations

Systematic Replacement of Amino Acid Residues within an Arg-Gly-Asp-containing Loop of Foot-and-Mouth Disease Virus and Effect on Cell Recognition

1996 • 126 citations

Implications of a quasispecies genome structure: effect of frequent, naturally occurring amino acid substitutions on the antigenicity of foot-and-mouth disease virus.

1989 • 124 citations

Distinct repertoire of antigenic variants of foot-and-mouth disease virus in the presence or absence of immune selection

1993 • 119 citations

Reactivity with monoclonal antibodies of viruses from an episode of foot-and-mouth disease

1987 • 116 citations

Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites

1994 • 115 citations

Unique amino acid substitutions in the capsid proteins of foot-and-mouth disease virus from a persistent infection in cell culture

1990 • 104 citations

Extensive antigenic heterogeneity of foot-and-mouth disease virus of serotype C

1988 • 103 citations

Direct evaluation of the immunodominance of a major antigenic site of foot-and-mouth disease virus in a natural host

1995 • 91 citations

A Similar Pattern of Interaction for Different Antibodies with a Major Antigenic Site of Foot-and-Mouth Disease Virus: Implications for Intratypic Antigenic Variation

1998 • 72 citations

Two mechanisms of antigenic diversification of foot-and-mouth disease virus

1991 • 65 citations

Rapid Selection in Modified BHK-21 Cells of a Foot-and-Mouth Disease Virus Variant Showing Alterations in Cell Tropism

1998 • 65 citations

Point mutations within the betaG-betaH loop of foot-and-mouth disease virus O1K affect virus attachment to target cells

1997 • 57 citations

Flexibility of the Major Antigenic Loop of Foot-and-Mouth Disease Virus Bound to a Fab Fragment of a Neutralising Antibody: Structure and Neutralisation

1999 • 55 citations

Selection of Antigenic Variants of Foot-and-Mouth Disease Virus in the Absence of Antibodies, as Revealed by an in situ Assay

1989 • 55 citations

Induced Pocket to Accommodate the Cell Attachment Arg-Gly-Asp Motif in a Neutralizing Antibody Against Foot-and-Mouth-Disease Virus

1996 • 52 citations

Recognition Sites of RGD-Dependent Integrins

1997 • 51 citations

Genetic and phenotypic variability during replication of foot-and-mouth disease virus in swine

1990 • 47 citations

Genetic variation of foot-and-mouth disease virus during persistent infection in cattle

1994 • 46 citations

In vivo analysis of the stability and fitness of variants recovered from foot-and-mouth disease virus quasispecies.

1998 • 41 citations

Antibodies Raised in a Natural Host and Monoclonal Antibodies Recognize Similar Antigenic Features of Foot-and-Mouth Disease Virus

1995 • 36 citations

Modification of foot-and-mouth disease virus O1 Caseros after serial passages in the presence of antiviral polyclonal sera

1992 • 36 citations

Use of substituted and tandem‐repeated peptides to probe the relevance of the highly conserved RGD tripeptide in the immune response against foot‐and‐mouth disease virus

1993 • 34 citations

Differential restrictions on antigenic variation among antigenic sites of foot-and-mouth disease virus in the absence of antibody selection.

1997 • 31 citations

Antibody and host cell recognition of foot-and-mouth disease virus (serotype C) cleaved at the Arg-Gly-Asp (RGD) motif: a structural interpretation

1996 • 30 citations

Generation of a subtype-specific neutralization epitope in foot-and-mouth disease virus of a different subtype

1992 • 29 citations

Synthetic peptides mimic subtype specificity of foot‐and‐mouth disease virus

1983 • 19 citations

Dissociation of carcinogen-induced SV40 DNA-Amplification and amplification of AAV DNA in a Chinese hamster cell line

1988 • 15 citations

Respuesta inmune frente a distintos antígenos del virus de la fiebre aftosa: variantes virales obtenidas en presencia o ausencia de selección por anticuerpos específicos

1993 • 1 citations