The Netrin 1 ReceptorsUnc5h3andDccAre Necessary at Multiple Choice Points for the Guidance of Corticospinal Tract Axons

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

1996 • 1,253 citations

Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor

1996 • 982 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene

1997 • 764 citations

RETRACTED: A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion

1999 • 686 citations

RETRACTED: Hierarchical Organization of Guidance Receptors: Silencing of Netrin Attraction by Slit Through a Robo/DCC Receptor Complex

2001 • 603 citations

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

1997 • 511 citations

UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues

1996 • 491 citations

frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance

1996 • 456 citations

Vertebrate Slit, a Secreted Ligand for the Transmembrane Protein Roundabout, Is a Repellent for Olfactory Bulb Axons

1999 • 444 citations

Netrin-1 and DCC Mediate Axon Guidance Locally at the Optic Disc: Loss of Function Leads to Optic Nerve Hypoplasia

1997 • 434 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1

1998 • 398 citations

Defining brain wiring patterns and mechanisms through gene trapping in mice

2001 • 391 citations

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

1997 • 372 citations

Neuroglia and Pioneer Neurons Express UNC-6 to Provide Global and Local Netrin Cues for Guiding Migrations in C. elegans

1996 • 359 citations

Short- and Long-Range Repulsion by the Drosophila Unc5 Netrin Receptor

2001 • 305 citations

EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract

1998 • 301 citations

Turning of Retinal Growth Cones in a Netrin-1 Gradient Mediated by the Netrin Receptor DCC

1997 • 280 citations

Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control

2001 • 251 citations

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

1993 • 237 citations

RETRACTED: Binding of DCC by Netrin-1 to Mediate Axon Guidance Independent of Adenosine A2B Receptor Activation

2001 • 237 citations

The DCC Gene: Structural Analysis and Mutations in Colorectal Carcinomas

1994 • 224 citations

Suppressors of Ectopic UNC-5 Growth Cone Steering Identify Eight Genes Involved in Axon Guidance inCaenorhabditis elegans

1998 • 175 citations

Directed Growth of Early Cortical Axons Is Influenced by a Chemoattractant Released from an Intermediate Target

1997 • 160 citations

The development of the corticospinal projection

1992 • 143 citations

DCC and netrins

1998 • 137 citations

Axon guidance at choice points

1998 • 136 citations

Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion during the formation of the rostral cerebellar boundary

1998 • 124 citations

Expression of the Netrin-1 receptor, deleted in colorectal cancer (DCC), is largely confined to projecting neurons in the developing forebrain

2000 • 95 citations

Cellular mechanisms of netrin function: Long-range and short-range actions

2000 • 92 citations

Adhesion and signaling in axonal fasciculation

1998 • 92 citations

Genetic composition of the recombinant congenic strains

1996 • 89 citations

Multiple Signaling Mechanisms of the UNC-6/netrin Receptors UNC-5 and UNC-40/DCC in Vivo

2001 • 84 citations

Cellular mechanisms of netrin function: Long-range and short-range actions

2000 • 71 citations

Postnatal growth of corticospinal axons in the spinal cord of developing mice

1999 • 68 citations

Interacting genes that affect microtubule function: the nc2 allele of the haywire locus fails to complement mutations in the testis-specific beta-tubulin gene of Drosophila.

1988 • 61 citations

Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo.

1995 • 54 citations

Immunohistochemical detection of calcium/calmodulin‐dependent protein kinase II in the spinal cord of the rat and monkey with special reference to the corticospinal tract

1994 • 41 citations

A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18

1992 • 39 citations

A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion

2022 • 35 citations

Interacting genes that affect microtubule function in Drosophila melanogaster: two classes of mutation revert the failure to complement between haync2 and mutations in tubulin genes.

1990 • 27 citations

An ultrastructural double-labelling method: immunohistochemical localization of cell adhesion molecule L1 on HRP-labelled developing corticospinal tract axons in the rat

1990 • 10 citations

frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance

1997 • 3 citations