Quantification of urinary o,o′-dityrosine, a biomarker for oxidative damage to proteins, by high performance liquid chromatography with triple quadrupole tandem mass spectrometryA comparison with ion-trap tandem mass spectrometry

NADPH Oxidase: An Update

1999 • 2,134 citations

Oxygen Metabolism and the Toxic Properties of Phagocytes

1980 • 886 citations

Electrochemical Analysis of Protein Nitrotyrosine and Dityrosine in the Alzheimer Brain Indicates Region-Specific Accumulation

1998 • 507 citations

Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.

1993 • 486 citations

Mass Spectrometric Quantification of Markers for Protein Oxidation by Tyrosyl Radical, Copper, and Hydroxyl Radical in Low Density Lipoprotein Isolated from Human Atherosclerotic Plaques

1997 • 355 citations

Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.

1993 • 345 citations

Mass Spectrometric Quantification of 3-Nitrotyrosine, ortho-Tyrosine, and o,o′-Dityrosine in Brain Tissue of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated Mice, a Model of Oxidative Stress in Parkinson's Disease

1999 • 264 citations

Tyrosine oxidation products: analysis and biological relevance

2003 • 228 citations

Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation

1993 • 222 citations

Dityrosine and tyrosine oxidation products are endogenous markers for the selective proteolysis of oxidatively modified red blood cell hemoglobin by (the 19 S) proteasome.

1993 • 197 citations

The myoglobin protein radical. Coupling of Tyr-103 to Tyr-151 in the H2O2-mediated cross-linking of sperm whale myoglobin.

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[39] Dityrosine: A marker for oxidatively modified proteins and selective proteolysis

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Characterization of a new type of cross-linkage in resilin, a rubber-like protein

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Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine

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Simultaneous determination of tyrosine, phenylalanine and deoxyguanosine oxidation products by liquid chromatography–tandem mass spectrometry as non-invasive biomarkers for oxidative damage

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Heme Protein Radicals

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Evaluation of a Multi-parameter Biomarker Set for Oxidative Damage in Man: Increased Urinary Excretion of Lipid, Protein and DNA Oxidation Products after One Hour of Exercise

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Evidence for dityrosine in elastin

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Oxidized amino acids: culprits in human atherosclerosis and indicators of oxidative stress 1,2 1This article is part of a series of reviews on “Oxidatively Modified Proteins in Aging and Disease.” The full list of papers may be found on the homepage of the journal. 2Guest Editor: Earl Stadtman

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Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques

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[25] Role of oxidized amino acids in protein breakdown and stability

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Role of the Carbonate Radical Anion in Tyrosine Nitration and Hydroxylation by Peroxynitrite

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Formation of insoluble gels and dityrosine by the action of peroxidase on soluble collagens

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Characterization of a DL-dityrosine-containing macromolecule from yeast ascospore walls.

1990 • 77 citations

Immunochemical Detection of Protein Dityrosine in Atherosclerotic Lesion of Apo-E-Deficient Mice Using a Novel Monoclonal Antibody

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Isolation of insoluble secretory product from bovine thyroid: extracellular storage of thyroglobulin in covalently cross-linked form.

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NADPH Oxidase of Neutrophils Elevates o,o′-Dityrosine Cross-Links in Proteins and Urine during Inflammation

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Quantification ofo,o‘-Dityrosine,o-Nitrotyrosine, ando-Tyrosine in Cat Urine Samples by LC/Electrospray Ionization-MS/MS Using Isotope Dilution

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Candida albicans cell walls contain the fluorescent cross-linking amino acid dityrosine

1995 • 44 citations

Tyrosine-Derived Cross-Linking Amino Acids in the Sheath of Haemonchus contortus Infective Larvae

1990 • 35 citations