Relationships Among Lactate Concentration, Blood Flow and Histopathologic Profiles in Rat C6 Glioma

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

1989 • 3,308 citations

Residuals and Influence in Regression.

1983 • 1,919 citations

Practical methods for biological morphometry

1979 • 1,498 citations

Tumor Mitochondria and the Bioenergetics of Cancer Cells

2015 • 720 citations

Textbook of Medical Physiology

1956 • 472 citations

Enzymology of Cancer Cells

1977 • 420 citations

Cerebral necrosis after radiotherapy and/or intraarterial chemotherapy for brain tumors: PET and neuropathologic studies

1988 • 420 citations

Prediction of survival in glioma patients by means of positron emission tomography

1985 • 407 citations

Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors.

1989 • 402 citations

Positron emission tomography in patients with glioma a predictor of prognosis

1988 • 378 citations

Heterogeneous oxygen partial pressure and pH distribution in C3H mouse mammary adenocarcinoma.

1981 • 339 citations

Sampling designs for stereology*

1981 • 334 citations

Does FDG uptake measure proliferative activity of human cancer cells? In vitro comparison with DNA flow cytometry and tritiated thymidine uptake.

1993 • 315 citations

Quantitation of proton NMR spectra of the human brain using tissue water as an internal concentration reference

1993 • 301 citations

Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain.

1982 • 292 citations

Symmetric pulses to induce arbitrary flip angles with compensation for rf inhomogeneity and resonance offsets

1991 • 274 citations

Microautoradiographic study for the differentiation of intratumoral macrophages, granulation tissues and cancer cells by the dynamics of fluorine-18-fluorodeoxyglucose uptake.

1994 • 267 citations

Metabolic imaging of patients with intracranial tumors: H-1 MR spectroscopic imaging and PET.

1990 • 262 citations

Florodeoxyglucose imaging: A method to assess the proliferative activity of human cancer in vivo. Comparison with DNA flow cytometry in head and neck tumors

1988 • 258 citations

Glucose utilization by intracranial meningiomas as an index of tumor aggressivity and probability of recurrence: a PET study.

1987 • 252 citations

THE CARBOHYDRATE METABOLISM OF TUMORS

1925 • 234 citations

Glucose uptake, perfusion, and cell proliferation in head and neck tumors: relation of positron emission tomography to flow cytometry.

1991 • 229 citations

In vivo disturbance of the oxidative metabolism of glucose in human cerebral gliomas

1983 • 203 citations

Correlation of glucose consumption and tumor cell density in astrocytomas

1993 • 148 citations

Application of Quantitative Autoradiographic Measurements in Experimental Brain Tumor Models

1981 • 138 citations

Glucose consumption by transplanted tumors in vivo.

1967 • 133 citations

Glucose uptake, lactate release, ketone body turnover, metabolic micromilieu, and pH distributions in human breast cancer xenografts in nude rats.

1988 • 130 citations

In vivo imaging of glucose consumption and lactate concentration in human gliomas

1992 • 130 citations

Glucose metabolism in drug-sensitive and drug-resistant human breast cancer cells monitored by magnetic resonance spectroscopy.

1988 • 128 citations

Issues in the in vivo measurement of glucose metabolism of human central nervous system tumors

1984 • 112 citations

A method to obtain infusion schedules for prescribed blood concentration time courses

1976 • 104 citations

The relationship between regional variations in blood flow and histology in a transplanted rat fibrosarcoma

1990 • 91 citations

The vasculature of experimental brain tumours

1981 • 86 citations

Quantitative determination of tumor blood flow and perfusion via deuterium nuclear magnetic resonance spectroscopy in mice.

1988 • 77 citations

Localized detection of glioma glycolysis using edited ¹H MRS

1993 • 76 citations

Regional metabolism of experimental brain tumors

1986 • 75 citations

Methods of counting discrete tissue components in microscopical sections

1967 • 70 citations

The vasculature of experimental brain tumours

1981 • 65 citations

Oxygen consumption and anaerobic glycolysis of human malignant and normal tissue.

1962 • 60 citations

Role of oxygen vs. glucose in energy metabolism in a mammary carcinoma perfused ex vivo: direct measurement by 31P NMR.

1993 • 54 citations

Regional blood flow in RT-9 brain tumors

1983 • 53 citations

Intracellular acidosis in murine fibrosarcomas coincides with ATP depletion, hypoxia, and high levels of lactate and total P_i

1994 • 50 citations

Spectral Editing with Adiabatic Pulses

1995 • 46 citations

Deuterium Magnetic Resonance in Vivo: The Measurement of Blood Flow and Tissue Perfusiona

1987 • 45 citations

Respiratory Patterns in Human Brain Tumors

1986 • 43 citations

Relative volume‐average murine tumor blood flow measurement via deuterium nuclear magnetic resonance spectroscopy

1991 • 38 citations

Spatially localized in vivo¹H magnetic resonance spectroscopy of an intracerebral rat glioma

1992 • 38 citations

Deuterium nuclear magnetic resonance imaging of tracer distribution in D2O clearance measurements of tumor blood flow in mice.

1990 • 36 citations

In Vivo ³¹P and ¹H NMR studies of rat brain tumor pH and blood flow during acute hyperglycemia: Differential effects between subcutaneous and intracerebral locations

1989 • 34 citations

B1-insensitive heteronuclear adiabatic polarization transfer for signal enhancement

1992 • 30 citations

Concurrent quantification of tissue metabolism and blood flow via ²h/³¹P NMR in Vivo. 11. validation of the deuterium nmr washout method for measuring organ perfusion

1992 • 14 citations

Mechanisms of Disease. A Textbook of Comparative General Pathology

1983 • 11 citations

An NMR View of Primary T-Lymphocyte Activation

1994 • 4 citations

Stereology in the extraction of information from images.

1985 • 3 citations

Theoretical aspects of diagnostic histopathology and their relation to morphometry.

1985 • 3 citations