An NMR View of Primary T-Lymphocyte Activation

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Intracellular pH.

1981 • 2,440 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Cytoplasmic pH and free Mg2+ in lymphocytes.

1982 • 1,047 citations

Metabolic regulation via intracellular pH

1984 • 674 citations

GLUTAMINE METABOLISM IN LYMPHOCYTES: ITS BIOCHEMICAL, PHYSIOLOGICAL AND CLINICAL IMPORTANCE

1985 • 455 citations

Aerobic glycolysis during lymphocyte proliferation

1976 • 317 citations

Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport.

1985 • 254 citations

Maximum activities of some enzymes of glycolysis, the tricarboxylic acid cycle and ketone-body and glutamine utilization pathways in lymphocytes of the rat

1982 • 217 citations

Oxygen and healing

1969 • 210 citations

Intracellular calcium measurements by 19F NMR of fluorine-labeled chelators.

1983 • 190 citations

Ion transport, membrane potential, and cytoplasmic pH in lymphocytes: changes during activation

1989 • 187 citations

Voltage‐gated potassium conductance in human T lymphocytes stimulated with phorbol ester.

1986 • 151 citations

Metabolic changes in activated T cells: An NMR study of human peripheral blood lymphocytes

1993 • 128 citations

Intracellular pH controls growth factor-induced ribosomal protein S6 phosphorylation and protein synthesis in the G0→G1 transition of fibroblasts

1986 • 126 citations

Human T lymphocyte activation by tumor promoters: role of protein kinase C.

1987 • 106 citations

Relationship between cytoplasmic pH and proliferation during exponential growth and cellular quiescence

1987 • 102 citations

Free cytosolic Ca2+ measurements with fluorine labelled indicators using 19FNMR

1985 • 102 citations

Determination of metabolite and nucleotide concentrations in proliferating lymphocytes by 1H-NMR of acid extracts

1990 • 98 citations

Evidence for voltage modulation of IL-2 production in mitogen-stimulated human peripheral blood lymphocytes.

1992 • 95 citations

Mitogen‐independent activation of Na⁺/H⁺ exchange in human epidermoid carcinoma A431 cells: Regulation by medium osmolarity

1985 • 92 citations

Internal pH-sensitive site couples Cl-(-)HCO3- exchange to Na+-H+ antiport in lymphocytes

1989 • 79 citations

Regulation of intracellular pH by human peripheral blood lymphocytes as measured by 19F NMR.

1982 • 79 citations

Characterization of lipid composition in stimulated human lymphocytes by 1H-NMR

1990 • 75 citations

Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells.

1988 • 71 citations

Fluorinated alpha-methylamino acids as 19F NMR indicators of intracellular pH

1983 • 60 citations

Modulation of K+ currents in human lymphocytes by pH.

1989 • 59 citations

Regulation of intracellular pH in BALB/c 3T3 cells. Bicarbonate raises pH via NaHCO3/HCl exchange and attenuates the activation of Na+/H+ exchange by serum

1991 • 56 citations

Cell Volume Regulation in Lymphocytes

1988 • 49 citations

Lymphocyte activation.

1976 • 47 citations

pH homeostasis in human lymphocytes: modulation by ions and mitogen.

1984 • 47 citations

Intracellular pH as Measured by ¹⁹F NMRa

1987 • 43 citations

Development of the “activated” high resolution ¹H MR spectrum in murine T cells and B cells occurs in G₁ phase of the cell cycle

1990 • 37 citations

Bicarbonate abolishes intracellular alkalinization in mitogen‐stimulated 3T3 cells

1989 • 32 citations

An NMR investigation of the changes in plasma membrane triglyceride and phospholipid precursors during the activation of T-lymphocytes

1992 • 28 citations

A comparison of the chemical analyses of cell lipids with their complete proton NMR spectrum

1987 • 25 citations

Lymphocyte activation and phospholipid pathways. 31P magnetic resonance studies

1991 • 25 citations

19F-NMR study of primary human T lymphocyte activation: effects of mitogen on intracellular pH

1994 • 19 citations

Metabolism of peripheral lymphocytes, interleukin‐2‐activated lymphocytes and tumor‐infiltrating lymphocytes from ³¹ NMR studies

1989 • 17 citations

Inhibition of lymphocyte stimulation by shift reagents

1990 • 14 citations

Stimulation of leucine transport by a mitogen through intracellular Ca2+ increase in human peripheral lymphocytes

1988 • 13 citations

Interaction of HIV‐1 with susceptible lymphoblastoid cells ¹H NMR studies

1991 • 11 citations

Chapter 16 Activation of Sodium—Hydrogen Exchange by Mitogens

1989 • 11 citations

The role of intracellular pH in insulin action.

1981 • 11 citations

Identification of phosphorylethanolamine in 31P-NMR spectra of human peripheral blood lymphocytes

1986 • 11 citations

Rapid acceleration of deoxyglucose transport by phorbol esters in bovine lymphocytes

1982 • 10 citations

Biochemical changes taking place in mitogen-treated lymphocytes

1987 • 7 citations

Metabolic and structural effects of HIV infection in human peripheral blood mononuclear cells can be monitored with 1H NMR spectroscopy.

1991 • 6 citations

Chapter 9 Role of Intracellular pH in Lymphocyte Activation

1990 • 3 citations

Lymphocyte metabolism and cytotoxic activity monitored with 31P magnetic resonance spectroscopy.

1990 • 3 citations

1H-nuclear magnetic resonance (NMR) spectroscopic study of B lymphocytes stimulated with lipopolysaccharide (LPS).

1988 • 1 citations