Thyroid Hormone Receptors Form Distinct Nuclear Protein-Dependent and Independent Complexes with a Thyroid Hormone Response Element

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Steroid Receptor Family: Structure and Functions

1990 • 820 citations

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

1988 • 705 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer

1989 • 508 citations

Identification of a tHyroid Hormone Receptor That Is Pituitary-Specific

1989 • 493 citations

Modular structure of a chicken lysozyme silencer: Involvement of an unusual thyroid hormone receptor binding site

1990 • 487 citations

Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing

1989 • 437 citations

Molecular Basis of Thyroid Hormone Action

1983 • 434 citations

Identification of a Novel Thyroid Hormone Receptor Expressed in the Mammalian Central Nervous System

1987 • 429 citations

Thyroid hormone receptor α isoforms generated by alternative splicing differentially activate myosin HC gene transcription

1988 • 425 citations

The N-terminal region of the chicken progesterone receptor specifies target gene activation

1988 • 425 citations

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

1989 • 387 citations

Regulation of gene expression by thyroid hormone.

1988 • 317 citations

Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity

1989 • 308 citations

Alternative splicing generates messages encoding rat c-erbA proteins that do not bind thyroid hormone.

1988 • 300 citations

A Domain Containing Leucine-Zipper-Like Motifs Mediate Novelin VivoInteractions between the Thyroid Hormone and Retinoic Acid Receptors

1989 • 293 citations

Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells.

1982 • 280 citations

Hormonal regulation of the growth hormone gene. Relationship of the rate of transcription to the level of nuclear thyroid hormone-receptor complexes.

1984 • 259 citations

Identification of a Rat c-erbAα-Related Protein Which Binds Deoxyribonucleic Acid but does not Bind Thyroid Hormone

1988 • 254 citations

The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein.

1989 • 245 citations

A Novel Thyroid Hormone Receptor Encoded by a cDNA Clone from a Human Testis Library

1987 • 242 citations

Mutations of the Rat Growth Hormone Promoter which Increase and Decrease Response to Thyroid Hormone Define a Consensus Thyroid Hormone Response Element

1989 • 240 citations

Isolation and characterization of rat cDNA clones for two distinct thyroid hormone receptors.

1988 • 237 citations

Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor.

1988 • 225 citations

Negative regulation of the thyroid-stimulating hormone alpha gene by thyroid hormone: receptor interaction adjacent to the TATA box.

1989 • 222 citations

Identification of Nuclear Factors that Enhance Binding of the Thyroid Hormone Receptor to a Thyroid Hormone Response Element

1989 • 219 citations

Thyroid Hormone Regulates the Mouse Thyrotropin β-Subunit Gene Promoter in Transfected Primary Thyrotropes

1989 • 203 citations

A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements.

1990 • 192 citations

Identification of a thyroid hormone response element in the malic enzyme gene.

1990 • 182 citations

Trans-activation by thyroid hormone receptors: functional parallels with steroid hormone receptors.

1989 • 154 citations

Thyroid hormone regulates expression of a transfected human alpha-myosin heavy-chain fusion gene in fetal rat heart cells.

1990 • 147 citations

Activation of protein kinase C or cAMP-dependent protein kinase increases phosphorylation of the c-erbA-encoded thyroid hormone receptor and of the v-erbA-encoded protein.

1988 • 136 citations

c-erbA Protooncogenes Mediate Thyroid Hormone-Dependent and Independent Regulation of the Rat Growth Hormone and Prolactin Genes

1988 • 133 citations

Characterization of a thyroid hormone receptor expressed in human kidney and other tissues.

1988 • 132 citations

Human carboxyl-terminal variant of alpha-type c-erbA inhibits trans-activation by thyroid hormone receptors without binding thyroid hormone.

1989 • 129 citations

A major thyroid hormone response element in the third intron of the rat growth hormone gene.

1990 • 123 citations

Thyroid Hormone Inhibition of Human Thyrotropin β-Subunit Gene Expression is Mediated by a Cis-acting Element Located in the First Exon

1989 • 119 citations

Thyroid Hormone Regulation of the Rat Glycoprotein Hormone α-Subunit Gene Promoter Activity

1989 • 99 citations

The thyroid hormone receptor binds to multiple domains of the rat growth hormone 5′-flanking sequence.

1988 • 77 citations

Mutational Analysis Identifies a New Functional Domain of the Thyroid Hormone Receptor

1990 • 70 citations

Binding of Thyroid Hormone Receptors to the Rat Thyrotropin-β Gene

1989 • 63 citations

Sequences Essential for Activity of the Thyroid Hormone Responsive Transcription Stimulatory Element of the Rat Growth Hormone Gene

1988 • 35 citations