Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

1999 • 2,950 citations

Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

2005 • 1,111 citations

CD1: Antigen Presentation and T Cell Function

2004 • 1,025 citations

Recognition of a lipid antigen by CD1-restricted αβ+ T cells

1994 • 976 citations

Lysosomal Glycosphingolipid Recognition by NKT Cells

2004 • 946 citations

Recognition of bacterial glycosphingolipids by natural killer T cells

2005 • 918 citations

CD1 Recognition by Mouse NK1 ⁺ T Lymphocytes

1995 • 903 citations

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity

2003 • 706 citations

Mechanism of CD1d-restricted natural killer T cell activation during microbial infection

2003 • 670 citations

Oxazolone Colitis, a Th2 Colitis Model Resembling Ulcerative Colitis, Is Mediated by IL-13-Producing NK-T Cells

2002 • 639 citations

CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

1992 • 577 citations

Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly

2003 • 530 citations

Assembly of MHC class I molecules analyzed in vitro

1990 • 491 citations

Murine CD1d-Restricted T Cell Recognition of Cellular Lipids

2000 • 467 citations

CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection

2000 • 440 citations

Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice

1999 • 415 citations

Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells

2004 • 375 citations

Human NKT Cells Mediate Antitumor Cytotoxicity Directly by Recognizing Target Cell CD1d with Bound Ligand or Indirectly by Producing IL-2 to Activate NK Cells

2001 • 351 citations

CD1d-dependent Activation of NKT Cells Aggravates Atherosclerosis

2004 • 327 citations

Editing of CD1d-Bound Lipid Antigens by Endosomal Lipid Transfer Proteins

2003 • 310 citations

CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung

2002 • 309 citations

The Role of the Microsomal Triglygeride Transfer Protein in Abetalipoproteinemia

2000 • 302 citations

Glycolipid Antigen Processing for Presentation by CD1d Molecules

2001 • 289 citations

Cd1-Restricted Nk T Cells Protect Nonobese Diabetic Mice from Developing Diabetes

2001 • 273 citations

An MTP Inhibitor That Normalizes Atherogenic Lipoprotein Levels in WHHL Rabbits

1998 • 267 citations

T Cell Activation by Lipopeptide Antigens

2004 • 262 citations

Cytoplasmic Tail-Dependent Localization of CD1b Antigen-Presenting Molecules to MIICs

1996 • 227 citations

CD1-dependent dendritic cell instruction

2002 • 215 citations

CD1d Endosomal Trafficking Is Independently Regulated by an Intrinsic CD1d-Encoded Tyrosine Motif and by the Invariant Chain

2001 • 207 citations

Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells

2004 • 202 citations

A Subset of Liver NK T Cells Is Activated duringLeishmania donovaniInfection by CD1d-bound Lipophosphoglycan

2004 • 198 citations

Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability.

1994 • 196 citations

Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail–truncated CD1d

2001 • 192 citations

CD1d structure and regulation on human thymocytes, peripheral blood T cells,B cells and monocytes

2000 • 190 citations

CD1d function is regulated by microsomal triglyceride transfer protein

2004 • 171 citations

Microsomal Triglyceride Transfer Protein

1995 • 157 citations

Binding and Antigen Presentation of Ceramide-Containing Glycolipids by Soluble Mouse and Human Cd1d Molecules

1999 • 154 citations

An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells.

1996 • 151 citations

Structural Features of the Acyl Chain Determine Self-phospholipid Antigen Recognition by a CD1d-restricted Invariant NKT (iNKT) Cell

2003 • 137 citations

Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence

1998 • 120 citations

Lipid Protein Interactions: The Assembly of CD1d1 with Cellular Phospholipids Occurs in the Endoplasmic Reticulum

2002 • 117 citations

Calnexin, Calreticulin, and ERp57 Cooperate in Disulfide Bond Formation in Human CD1d Heavy Chain

2002 • 116 citations

Human invariant Vα24⁺ natural killer T cells activated by α‐galactosylceramide (KRN7000) have cytotoxic anti‐tumour activity through mechanisms distinct from T cells and natural killer cells

2000 • 114 citations

Low expression level but potent antigen presenting function of CD1d on monocyte lineage cells

2000 • 109 citations

CD1d-restricted T cells regulate dendritic cell function and antitumor immunity in a granulocyte–macrophage colony-stimulating factor-dependent fashion

2003 • 103 citations

Biochemical Characterization of CD1d Expression in the Absence of β2-Microglobulin

1999 • 95 citations

A simple, rapid, and sensitive fluorescence assay for microsomal triglyceride transfer protein

2004 • 94 citations

Innate immune response to encephalomyocarditis virus infection mediated by CD1d

2003 • 82 citations

Delineation of a CD1d-restricted antigen presentation pathway associated with human and mouse intestinal epithelial cells

2003 • 78 citations

Lipid–protein interactions: Biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved

2004 • 76 citations

A Novel Series of Highly Potent Benzimidazole-Based Microsomal Triglyceride Transfer Protein Inhibitors

2001 • 59 citations

Decreased Secretion of ApoB Follows Inhibition of ApoB−MTP Binding by a Novel Antagonist

2000 • 56 citations

Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein

2005 • 51 citations

Identification of Two Classes of Lipid Molecule Binding Sites on the Microsomal Triglyceride Transfer Protein

1994 • 49 citations

Microsomal Triglyceride Transfer Protein Binding and Lipid Transfer Activities Are Independent of Each Other, but Both Are Required for Secretion of Apolipoprotein B Lipoproteins from Liver Cells

2001 • 45 citations

Microsomal triglyceride transfer protein expression in adipocytes: A new component in fat metabolism

2005 • 36 citations

Conservation of CD1 Intracellular Trafficking Patterns Between Mammalian Species

2002 • 23 citations

Human CD1d associates with prolyl-4-hydroxylase during its biosynthesis

2000 • 9 citations