Characterization of In0 of Pseudomonas aeruginosa plasmid pVS1, an ancestor of integrons of multiresistance plasmids and transposons of gram-negative bacteria

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

A novel family of potentially mobile DNA elements encoding site‐specific gene‐integration functions: integrons

1989 • 880 citations

TRANSPOSABLE ELEMENTS IN PROKARYOTES

1981 • 765 citations

Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria

1983 • 426 citations

Site-specific recombination promotes linkage between trimethoprim- and sulfonamide resistance genes. Sequence characterization of dhfrV and sulI and a recombination active locus of Tn21

1988 • 252 citations

Codon usage inPseudomonas aeruginosa

1988 • 236 citations

Tn552, a novel transposable element from Staphylococcus aureus

1990 • 232 citations

Deoxyribonucleic acid sequence of a gene from the Pseudomonas transposon TN501 encoding mercuric reductase

1983 • 232 citations

Precise insertion of antibiotic resistance determinants into Tn21-like transposons: nucleotide sequence of the OXA-1 beta-lactamase gene.

1987 • 228 citations

Characterization of the nonenzymatic chloramphenicol resistance (cmlA) gene of the In4 integron of Tn1696: similarity of the product to transmembrane transport proteins

1991 • 182 citations

Genetic elements involved in Tn21 site-specific integration, a novel mechanism for the dissemination of antibiotic resistance genes.

1990 • 166 citations

Nucleotide sequence of the AAD(2′) aminoglycoside adenylyltransferase determinantaadB. Evolutionary relationship of this region with those surroundingaadAin R538-1 anddhfrllin R388

1986 • 164 citations

Characterization of a translocation unit encoding resistance to mercuric ions that occurs on a nonconjugative plasmid in Pseudomonas aeruginosa

1977 • 163 citations

Sequence of PSE-2 beta-lactamase

1988 • 156 citations

The nucleotide sequence of the mercuric resistance operons of plasmid R100 and transposon Tn501: further evidence for mer genes which enhance the activity of the mercuric ion detoxification system

1986 • 152 citations

Molecular characterization of two proteins involved in the excision of the conjugative transposon Tn1545: homologies with other site-specific recombinases.

1989 • 146 citations

On the evolution of Tn21-like multiresistance transposons: Sequence analysis of the gene (aacC1) for gentamicin acetyltransferase-3-I(AAC(3)-I), another member of the Tn21-based expression cassette

1989 • 138 citations

Genetic and molecular characterization of the Pseudomonas plasmid pVS1

1984 • 126 citations

The region of the incN plasmid R46 coding for resistance to β-lactam antibiotics, streptomycin/spectinomycin and sulphonamides is closely related to antibiotic resistance segments found In IncW plasm ids and in Tn21-like transposons

1987 • 121 citations

Physical and genetic analysis of the Inc-W group plasmids R388, Sa, and R7K

1982 • 103 citations

Evolution of complex resistance transposons from an ancestral mercury transposon

1983 • 94 citations

Nucleotide sequence of the transposon Tn7 gene encoding an aminoglycoside-modifying enzyme, 3″(9)-O-nucleotidyltransferase

1985 • 87 citations

DNA sequence of a plasmid-encoded dihydrofolate reductase

1981 • 82 citations

Homology of ORFs from Tn2603and from R46 to site-specific recombinases

1987 • 81 citations

Tn402: a new transposable element determining trimethoprim resistance that inserts in bacteriophage lambda

1977 • 74 citations

The dhfrI trimethoprim resistance gene of Tn7 can be found at specific sites in other genetic surroundings

1990 • 74 citations

Cloning and sequencing of a gene encoding an aminoglycoside 6'-N-acetyltransferase from an R factor of Citrobacter diversus

1988 • 72 citations

Molecular analysis of the pac gene encoding a puromycin N-acetyl transferase from Streptomyces alboniger

1989 • 70 citations

Nucleotide sequence of the PSE-4 carbenicillinase gene and correlations with the Staphylococcus aureus PC1 beta-lactamase crystal structure.

1990 • 64 citations

The aminoglycoside-resistance operon of the plasmid pSa: nucleotide sequence of the streptomycin-spectinomycin resistance gene

1985 • 59 citations

Characterization of a R plasmid-associated, trimethoprim-resistant dihydrofolate reductase and determination of the nucleotide sequence of the reductase gene

1981 • 57 citations

Isolation, characterization, and DNA sequence analysis of an AAC(6')-II gene from Pseudomonas aeruginosa

1989 • 55 citations

Nucleotide sequence analysis of 2″‐aminoglycoside nucleotidyl‐transferase ANT(2″) from Tn4000: its relationship with AAD(3″) and impact on Tn21 evolution

1988 • 54 citations

Insertions of resistance genes into Tn21-like transposons

1986 • 53 citations

Characterization of Tn2411 and Tn2410, two transposons derived from R-plasmid R1767 and related to Tn2603 and Tn21

1983 • 48 citations

DNA sequence analysis of five genes;tnsA, B, C, DandE, required for Tn7 transposition

1990 • 45 citations

Structural and functional characterization of tnpI, a recombinase locus in Tn21 and related beta-lactamase transposons

1990 • 44 citations

Structure and function of hot spots providing signals for site‐directed specific recombination and gene expression in Tn21 transposons

1989 • 43 citations

Evolutionary relationship between Tn21-like elements and pBP201, a plasmid from Klebsiella pneumoniae mediating resistance to gentamicin and eight other drugs

1984 • 42 citations

Development of a DNA probe from the deoxyribonucleotide sequence of a 3-N-aminoglycoside acetyltransferase [AAC(3)-I] resistance gene

1989 • 40 citations

Molecular Mechanisms for Transposition of Drug-Resistance Genes and Other Movable Genetic Elements

1987 • 38 citations

The Salmonella wien virulence plasmid pZM3 carries Tn1935, a multiresistance transposon containing a composite IS1936-kanamycin resistance element

1988 • 29 citations

Characterization of a plasmid isolated from Branhamella catarrhalis and detection of plasmid sequences within the genome of a B. catarrhalis strain

1988 • 26 citations

Expression of the sulfonamide resistance gene from plasmid R46

1990 • 26 citations

Nucleotide Sequence of an OXA-2 B-Lactamase Gene from the R-Plasmid R1767 Derived Plasmid pBP11 and Comparison to Closely Related Resistance Determinants Found in R46 and Tn2603

1989 • 23 citations

Evolution of Tn21-related Transposons: Isolation of Tn2425, which Harbours IS161

1985 • 14 citations

Genesis of a complex transposon encoding the OXA-1 (type II) beta-lactamase gene

1985 • 13 citations