Interaction of Glycogen Synthase Kinase 3β with the DF3/MUC1 Carcinoma-Associated Antigen and β-Catenin

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

1997 • 3,847 citations

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

1997 • 3,234 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

β-catenin is a target for the ubiquitin–proteasome pathway

1997 • 2,461 citations

XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos

1996 • 1,827 citations

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1991 • 1,686 citations

E-cadherin germline mutations in familial gastric cancer

1998 • 1,629 citations

A causal role for E-cadherin in the transition from adenoma to carcinoma

1998 • 1,415 citations

Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

1996 • 1,382 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Association of the APC Gene Product with β-Catenin

1993 • 1,215 citations

Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines

1997 • 1,215 citations

Association of the APC Tumor Suppressor Protein with Catenins

1993 • 1,202 citations

Armadillo Coactivates Transcription Driven by the Product of the Drosophila Segment Polarity Gene dTCF

1997 • 1,201 citations

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.

1996 • 1,156 citations

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

1995 • 1,025 citations

Nuclear localization of β-catenin by interaction with transcription factor LEF-1

1996 • 864 citations

Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule.

1990 • 753 citations

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.

1994 • 647 citations

A Homolog of the armadillo Protein in Drosophila (Plakoglobin) Associated with E-Cadherin

1991 • 632 citations

Differential Reactivity of a Novel Monoclonal Antibody (DF3) with Human Malignant versus Benign Breast Tumors

1984 • 583 citations

Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation

1994 • 578 citations

A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats.

1988 • 571 citations

A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes.

1996 • 542 citations

Monoclonal antibodies against human milk‐fat globule membranes detecting differentiation antigens of the mammary gland and its tumors

1984 • 510 citations

Glycogen synthase kinase‐3 and the Alzheimer‐like state of microtubule‐associated protein tau

1992 • 507 citations

pangolinencodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila

1997 • 494 citations

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

1995 • 492 citations

Apoptosis and APC in colorectal tumorigenesis.

1996 • 491 citations

LEF-1, a Nuclear Factor Coordinating Signaling Inputs from wingless and decapentaplegic

1997 • 450 citations

The APC gene product in normal and tumor cells.

1993 • 436 citations

Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin.

1989 • 436 citations

wingless signaling acts through zeste-white 3, the drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate

1992 • 425 citations

wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo

1994 • 423 citations

Multisite and hierarchal protein phosphorylation

1991 • 419 citations

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

1994 • 405 citations

The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules.

1994 • 398 citations

Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain

1992 • 394 citations

A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.

1996 • 389 citations

Components of wingless signalling in Drosophila

1994 • 326 citations

Suppression of cellular aggregation by high levels of episialin.

1992 • 321 citations

Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.

1995 • 321 citations

The APC Protein and E-cadherin Form Similar but Independent Complexes with α-Catenin, β-Catenin, and Plakoglobin

1995 • 315 citations

Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen.

1988 • 310 citations

Interaction of the DF3/MUC1 Breast Carcinoma-associated Antigen and β-Catenin in Cell Adhesion

1997 • 306 citations

E-cadherin mediated adhesion system in cancer cells

1996 • 281 citations

Phosphorylation of the Drosophila Adherens Junction Protein Armadillo: Roles for Wingless Signal and Zeste-white 3 Kinase

1994 • 251 citations

Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3

1995 • 233 citations

Loss of E-Cadherin-Dependent Cell-Cell Adhesion due to Mutation of the β-Catenin Gene in a Human Cancer Cell Line, HSC-39

1995 • 225 citations

Episialin (MUC1) inhibits cytotoxic lymphocyte-target cell interaction.

1993 • 221 citations

NH2-terminal Deletion of β-Catenin Results in Stable Colocalization of Mutant β-Catenin with Adenomatous Polyposis Coli Protein and Altered MDCK Cell Adhesion

1997 • 220 citations

Prognostic value of cadherin-associated molecules (alpha-, beta-, and gamma-catenins and p120cas) in bladder tumors.

1996 • 209 citations

Beta-catenin expression in human cancers.

1996 • 202 citations

Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells

1994 • 194 citations

Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein.

1995 • 188 citations

Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins Cytokine receptor‐like molecules

1994 • 155 citations

An early embryonic product of the gene shaggy encodes a serine/threonine protein kinase related to the CDC28/cdc2+ subfamily.

1990 • 154 citations

Frequent alterations in E-cadherin and alpha- and beta-catenin expression in human breast cancer cell lines.

1995 • 141 citations

Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines.

1998 • 135 citations

Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein

1997 • 124 citations

Tumor selective reactivity of a monoclonal antibody prepared against a recombinant peptide derived from the DF3 human breast carcinoma-associated antigen.

1992 • 102 citations

Frequent alteration of the DF3 tumor-associated antigen gene in primary human breast carcinomas.

1989 • 101 citations

Reactivity of monoclonal antibody DF3 with a high molecular weight antigen expressed in human ovarian carcinomas.

1986 • 53 citations

Deleted Work

1955 • 0 citations