Studies of NMDA Receptor Function and Stoichiometry with Truncated and Tandem Subunits

Glutamate receptor ion channels

2005 • 3,667 citations

NMDA receptor subunits: diversity, development and disease

2001 • 1,677 citations

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

2000 • 1,197 citations

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs

1992 • 1,067 citations

Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor

2000 • 870 citations

The Tetrameric Structure of a Glutamate Receptor Channel

1998 • 790 citations

Mechanism of glutamate receptor desensitization

2002 • 650 citations

Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

1998 • 487 citations

Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes

1990 • 461 citations

An NMDA Receptor ER Retention Signal Regulated by Phosphorylation and Alternative Splicing

2001 • 414 citations

Ligand-Gated Ion Channel Interactions with Cytoskeletal and Signaling Proteins

2000 • 352 citations

PDZ Domain Suppression of an ER Retention Signal in NMDA Receptor NR1 Splice Variants

2000 • 344 citations

Functional characterization of a potassium-selective prokaryotic glutamate receptor

1999 • 325 citations

Unraveling the modular design of glutamate-gated ion channels

1995 • 272 citations

Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors

1992 • 261 citations

Single‐channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors

1998 • 231 citations

Subunit Arrangement of γ-Aminobutyric Acid Type A Receptors

2001 • 211 citations

Desensitization at the frog neuromuscular junction: a biphasic process

1982 • 211 citations

Mutation of a glutamate receptor motif reveals its role in gating and δ2 receptor channel properties

2000 • 208 citations

Identification of Amino Acid Residues of the NR2A Subunit That Control Glutamate Potency in Recombinant NR1/NR2A NMDA Receptors

1998 • 199 citations

C-Terminal Truncation of NR2A Subunits Impairs Synaptic But Not Extrasynaptic Localization of NMDA Receptors

2000 • 184 citations

Functional Correlation of NMDA Receptor ε Subunits Expression with the Properties of Single-Channel and Synaptic Currents in the Developing Cerebellum

1996 • 175 citations

The Crystal Structure of Glutamine-binding Protein fromEscherichia coli

1996 • 162 citations

Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors

1995 • 143 citations

Constraining Ligand-Binding Site Stoichiometry Suggests that a Cyclic Nucleotide–Gated Channel Is Composed of Two Functional Dimers

1998 • 136 citations

An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits

2001 • 119 citations

Identification of Molecular Determinants That Are Important in the Assembly of N-Methyl-d-aspartate Receptors

2001 • 113 citations

Subunit interactions in coordination of Ni2+ in cyclic nucleotide-gated channels.

1995 • 111 citations

Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors

2002 • 109 citations

Coupling of Permeation and Gating in an NMDA-Channel Pore Mutant

1997 • 101 citations

Glycine-Independent NMDA Receptor Desensitization: Localization of Structural Determinants

1998 • 100 citations

Subunit Interactions and AMPA Receptor Desensitization

2001 • 99 citations

Intermediate Conductances during Deactivation of Heteromultimeric Shaker Potassium Channels

1998 • 96 citations

Oligomerization and Ligand-binding Properties of the Ectodomain of the α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunit GluRD

1999 • 95 citations

Tandem linkage of Shaker K+ channel subunits does not ensure the stoichiometry of expressed channels

1992 • 81 citations

Evidence for Dimerization of Dimers in K+ Channel Assembly

1999 • 80 citations

Chloride Channel Expression with the Tandem Construct of α6-β2 GABAA Receptor Subunit Requires a Monomeric Subunit of α6 or γ2

1995 • 80 citations

Functional Stoichiometry of Glutamate Receptor Desensitization

2002 • 77 citations

Pore stoichiometry of a voltage-gated chloride channel

1998 • 64 citations

A Site in the Fourth Membrane-associated Domain of the N-Methyl-d-aspartate Receptor Regulates Desensitization and Ion Channel Gating

2002 • 62 citations

Ionotropic glutamate receptors

1999 • 61 citations

Subconductance States of a Mutant NMDA Receptor Channel Kinetics, Calcium, and Voltage Dependence

1997 • 52 citations

Isolation of a Single Carboxyl-Carboxylate Proton Binding Site in the Pore of a Cyclic Nucleotide–Gated Channel

1999 • 43 citations

Constraining the subunit order of rod cyclic nucleotide-gated channels reveals a diagonal arrangement of like subunits

2000 • 31 citations

Identification of a Juxtamembrane Segment of the Glutamate Receptor δ2 Subunit Required for the Plasma Membrane Localization

2000 • 26 citations

The C‐terminal C1 cassette of the N‐methyl‐<scp>d</scp>‐aspartate receptor 1 subunit contains a bi‐partite nuclear localization sequence

2002 • 18 citations

Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers.

1998 • 4 citations

Kinetic properties of NMDA receptors in embryonic Xenopus spinal neurons

1995 • 3 citations