p27Kip1 induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

Principles of CDK regulation

1995 • 3,267 citations

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1998 • 2,427 citations

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1994 • 2,154 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1994 • 2,071 citations

Steroid hormone receptors: Many Actors in search of a plot

1995 • 1,854 citations

Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27

1995 • 1,848 citations

Mice Lacking p27 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

1996 • 1,583 citations

A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice

1996 • 1,488 citations

New functional activities for the p21 family of CDK inhibitors.

1997 • 1,414 citations

Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27

1996 • 1,283 citations

Radiation-induced cell cycle arrest compromised by p21 deficiency

1995 • 1,249 citations

D-type cyclin-dependent kinase activity in mammalian cells.

1994 • 1,073 citations

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas

1997 • 1,055 citations

Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats

1978 • 1,054 citations

Luciferase reporter gene vectors for analysis of promoters and enhancers.

1988 • 1,016 citations

AH RECEPTOR SIGNALING PATHWAYS

1996 • 898 citations

Translational Control of p27 ^Kip1 Accumulation During the Cell Cycle

1996 • 864 citations

Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.

1992 • 830 citations

Aryl-hydrocarbon Receptor-Deficient Mice Are Resistant to 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Toxicity

1996 • 820 citations

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

1998 • 796 citations

Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

1998 • 618 citations

Identification of a novel mechanism of regulation of Ah (dioxin) receptor function

1999 • 548 citations

Role of the Ah Receptor and the Dioxin‐Inducible [Ah] Gene Battery in Toxicity, Cancer, and Signal Transductiona

1993 • 425 citations

cDNA cloning and structure of mouse putative Ah receptor

1992 • 406 citations

The retinoblastoma protein pathway and the restriction point

1996 • 392 citations

Transcriptional cross-talk, the second mode of steroid hormone receptor action

1998 • 390 citations

DNA Binding Specificities and Pairing Rules of the Ah Receptor, ARNT, and SIM Proteins

1995 • 388 citations

Quantitative evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine.

1980 • 374 citations

Control of cell lineage-specific development and transcription by bHLH-PAS proteins

1998 • 347 citations

Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo.

1996 • 343 citations

Targets for Dioxin: Genes for Plasminogen Activator Inhibitor-2 and Interleukin-1β

1991 • 336 citations

D-Type Cyclin-Dependent Kinase Activity in Mammalian Cells

1994 • 322 citations

Cyclin dependent kinase regulation

1995 • 286 citations

A Direct Interaction between the Aryl Hydrocarbon Receptor and Retinoblastoma Protein

1998 • 249 citations

Rapamycin Resistance Tied to Defective Regulation of p27^Kip1

1996 • 213 citations

Regulation of thymocyte development from immature progenitors

1996 • 182 citations

Carcinogenicity of TCDD: Experimental, Mechanistic, and Epidemiologic Evidence

1994 • 169 citations

Complementation of Ah Receptor Deficiency in Hepatoma Cells: Negative Feedback Regulation and Cell Cycle Control by the Ah Receptor

1996 • 167 citations

ahr null alleles: distinctive or different?

1998 • 147 citations

Thymic Alterations Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Are Strictly Dependent on Aryl Hydrocarbon Receptor Activation in Hemopoietic Cells

1998 • 129 citations

A new pathway for mitogen-dependent Cdk2 regulation uncovered in p27Kip1-deficient cells

1999 • 120 citations

Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin

1994 • 108 citations

DNA Binding by the Heterodimeric Ah Receptor

1996 • 86 citations

The dioxin and peroxisome proliferator-activated receptors: nuclear receptors in search of endogenous ligands

1992 • 85 citations

Evidence for a second pathway in the action mechanism of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)

1995 • 80 citations

Cytokine Gene Expression during Ontogeny in Murine Thymus on Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

1997 • 68 citations

Characterization of the murine cyclin-dependent kinase inhibitor gene p27Kip1

1996 • 65 citations

Common threads in eukaryotic circadian systems

1998 • 52 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits DNA synthesis in rat primary hepatocytes*1

1995 • 45 citations

Inhibitory effects of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin on rat hepatocyte proliferation induced by 2/3 partial hepatectomy

1995 • 44 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin causes unbalanced growth in 5L rat hepatoma cells

1991 • 25 citations

The CDK inhibitor, p27Kip1, is required for IL-4 regulation of astrocyte proliferation.

1997 • 23 citations

Carboxyl-terminal Domain of p27Kip1 Activates CDC2

1997 • 20 citations

Receptor-mediated events and the evaluation of the Environmental Protection Agency (EPA) of dioxin risks*1

1995 • 20 citations

Identification of cdk2 binding sites on the p27Kip1 cyclin-dependent kinase inhibitor

1998 • 11 citations