Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit 1 1Edited by R. Huber

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

1997 • 10,943 citations

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

WHAT IF: A molecular modeling and drug design program

1990 • 3,484 citations

Automated MAD and MIR structure solution

1999 • 3,079 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

[16] SHELXL: High-resolution refinement

1997 • 2,469 citations

Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants

1998 • 2,394 citations

Satisfying Hydrogen Bonding Potential in Proteins

1994 • 2,076 citations

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1997 • 1,724 citations

Common themes in microbial pathogenicity revisited

1997 • 1,370 citations

Type III Secretion Machines: Bacterial Devices for Protein Delivery into Host Cells

1999 • 1,280 citations

The leucine-rich repeat: a versatile binding motif

1994 • 1,209 citations

Common themes in microbial pathogenicity revisited.

1997 • 782 citations

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

1993 • 614 citations

Disruption of Signaling by Yersinia Effector YopJ, a Ubiquitin-Like Protein Protease

2000 • 549 citations

Structural diversity of leucine-rich repeat proteins 1 1Edited by F. Cohen

1998 • 507 citations

Proteins with leucine-rich repeats

1995 • 388 citations

The PTPase YopH inhibits uptake ofYersinia, tyrosine phosphorylation of p130^Casand FAK, and the associated accumulation of these proteins in peripheral focal adhesions

1997 • 373 citations

Crystal structure of the spliceosomal U2B″–U2A′ protein complex bound to a fragment of U2 small nuclear RNA

1998 • 349 citations

GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structure

2000 • 334 citations

The RhoGAP activity of the Yersinia pseudotuberculosis cytotoxin YopE is required for antiphagocytic function and virulence

2000 • 324 citations

Salmonella typhimurium leucine‐rich repeat proteins are targeted to the SPI1 and SPI2 type III secretion systems

1999 • 274 citations

Functional conservation of the secretion and translocation machinery for virulence proteins of yersiniae, salmonellae and shigellae.

1995 • 205 citations

Identification of a Putative Salmonella enterica Serotype Typhimurium Host Range Factor with Homology to IpaH and YopM by Signature-Tagged Mutagenesis

1999 • 204 citations

A distinctive role for the Yersinia protein kinase: Actin binding, kinase activation, and cytoskeleton disruption

2000 • 201 citations

Status of YopM and YopN in the Yersinia Yop virulon: YopM of Y.enterocolitica is internalized inside the cytosol of PU5-1.8 macrophages by the YopB, D, N delivery apparatus.

1996 • 199 citations

YopM inhibits platelet aggregation and is necessary for virulence of Yersinia pestis in mice

1990 • 195 citations

Molecular and cell biology aspects of plague

2000 • 189 citations

Reciprocal-space solvent flattening

1999 • 178 citations

Targeting of the Yersinia pestis YopM protein into HeLa cells and intracellular trafficking to the nucleus

1998 • 172 citations

Structure of the InlB Leucine-Rich Repeats, a Domain that Triggers Host Cell Invasion by the Bacterial Pathogen L. monocytogenes

1999 • 166 citations

The Cytotoxin YopT of Yersinia enterocoliticaInduces Modification and Cellular Redistribution of the Small GTP-binding Protein RhoA

1999 • 159 citations

CROSS-TALK BETWEEN BACTERIAL PATHOGENS AND THEIR HOST CELLS

1996 • 153 citations

The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain

2000 • 146 citations

The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages

2000 • 138 citations

The Yersinia Ser/Thr protein kinase YpkA/YopO directly interacts with the small GTPases RhoA and Rac‐1

2000 • 133 citations

The Yersinia Protein Kinase A Is a Host Factor Inducible RhoA/Rac-binding Virulence Factor

2000 • 127 citations

The Crystal Structure of rna1p

1999 • 116 citations

Crystal structure of Rab geranylgeranyltransferase at 2.0 Å resolution

2000 • 108 citations

Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins

1998 • 108 citations

Identification of an amino‐terminal substrate‐binding domain in the Yersinia tyrosine phosphatase that is required for efficient recognition of focal adhesion targets

1998 • 104 citations

Type III machines of Gram-negative bacteria: delivering the goods

2000 • 81 citations

Structure of the N-terminal domain ofYersinia pestisYopH at 2.0 Å resolution

2001 • 43 citations

Structure–function analysis of Yersinia pestis YopM's interaction with α-thrombin to rule on its significance in systemic plague and to model YopM's mechanism of binding host proteins

2001 • 41 citations

Heterogeneity of theYersiniaYopM protein

1998 • 40 citations

Overproduction, purification, crystallization and preliminary X-ray diffraction analysis of YopM, an essential virulence factor extruded by the plague bacteriumYersinia pestis

2000 • 10 citations