A single point mutation has pleiotropic effects on pp60v-src function

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Protein kinase activity associated with the avian sarcoma virus src gene product.

1978 • 1,137 citations

Nucleotide sequence of rous sarcoma virus

1983 • 901 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

New procedure for DNA transfection with polycation and dimethyl sulfoxide.

1984 • 481 citations

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation.

1984 • 447 citations

A bacteriophage lambda vector for cloning large DNA fragments made with several restriction enzymes

1980 • 379 citations

The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins

1981 • 360 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src.

1985 • 304 citations

Cell Transformation by RNA Tumor Viruses

1977 • 298 citations

Identification of a polypeptide encoded by the avian sarcoma virus src gene.

1978 • 266 citations

Interaction of the Rous Sarcoma Virus Protein pp60 src with the Cellular Proteins pp50 and pp90

1986 • 223 citations

Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation

1986 • 223 citations

New Procedure for DNA Transfection with Polycation and Dimethyl Sulfoxide

1984 • 217 citations

Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src).

1981 • 203 citations

Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells

1980 • 184 citations

Evidence that the src gene product of rous sarcoma virus is membrane associated

1980 • 180 citations

The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity

1986 • 174 citations

Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the protein.

1984 • 173 citations

Association of the src gene product of Rous sarcoma virus with cytoskeletal structures of chicken embryo fibroblasts.

1980 • 169 citations

Transit of pp60v-src to the plasma membrane.

1982 • 165 citations

Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation.

1987 • 163 citations

Interaction Between the Rous Sarcoma Virus Transforming Protein and Two Cellular Phosphoproteins: Analysis of the Turnover and Distribution of This Complex

1983 • 162 citations

Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus.

1986 • 149 citations

A Short Sequence in the p60^src N Terminus Is Required for p60^src Myristylation and Membrane Association and for Cell Transformation

1984 • 149 citations

Antibodies against synthetic peptides as a tool for functional analysis of the transforming protein pp60src

1983 • 103 citations

The selective isolation of temperature-sensitive mutants of Rous sarcoma virus

1973 • 103 citations

Processing of p60v-src to its myristylated membrane-bound form.

1985 • 102 citations

Development of avian sarcoma and leukosis virus-based vector-packaging cell lines

1988 • 88 citations

N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene.

1985 • 88 citations

Phosphorylation of talin at tyrosine in Rous sarcoma virus-transformed cells.

1987 • 83 citations

Development of Anti-pp60 ^src Serum with Antigen Produced in Escherichia coli

1983 • 75 citations

Amino Acid Alterations Within a Highly Conserved Region of the Rous Sarcoma Virus src Gene Product pp60^src Inactivate Tyrosine Protein Kinase Activity

1984 • 75 citations

Myristic Acid Is Attached to the Transforming Protein of Rous Sarcoma Virus During or Immediately After Synthesis and Is Present in Both Soluble and Membrane-Bound Forms of the Protein

1984 • 73 citations

Genetic analysis of p60v-src domains involved in the induction of different cell transformation parameters

1986 • 58 citations

Transformation by the src oncogene alters glucose transport into rat and chicken cells by different mechanisms.

1988 • 56 citations

Genetic lesions involved in temperature sensitivity of the src gene products of four Rous sarcoma virus mutants

1986 • 56 citations

Biochemical properties of p60v-src mutants that induce different cell transformation parameters

1986 • 51 citations

The membrane-binding domain and myristylation of p60v-src are not essential for stimulation of cell proliferation

1987 • 48 citations

Genetic analysis of the form and function of the viral src oncogene product

1987 • 47 citations

Functional domains of the pp60v-src protein as revealed by analysis of temperature-sensitive Rous sarcoma virus mutants.

1984 • 45 citations

The use of Rous sarcoma virus transformation mutants with differing tyrosine kinase activities to study the relationships between vinculin phosphorylation, pp60v-src location and adhesion plaque integrity

1986 • 45 citations

Complementation of transforming functions by temperature-sensitive mutants of avion sarcoma virus

1973 • 45 citations

N-Terminal Deletions in Rous Sarcoma Virus p60^src: Effects on Tyrosine Kinase and Biological Activities and on Recombination in Tissue Culture with the Cellular src Gene

1985 • 44 citations

Processing of p60^v-src to Its Myristylated Membrane-Bound Form

1985 • 40 citations

Size-Variant pp60^src Proteins of Recovered Avian Sarcoma Viruses Interact with Adhesion Plaques as Peripheral Membrane Proteins: Effects on Cell Transformation

1984 • 40 citations

Phosphorylation of Talin at Tyrosine in Rous Sarcoma Virus-Transformed Cells

1987 • 34 citations

The Viral Tyrosine Protein Kinases

1986 • 31 citations

Intracellular localization and processing of pp60v-src proteins expressed by two distinct temperature-sensitive mutants of Rous sarcoma virus

1986 • 31 citations

Localization of temperature-sensitive transformation mutations and back mutations in the Rous sarcoma virus src gene

1986 • 25 citations

Mapping of nonconditional and conditional mutants in the src gene of Prague strain Rous sarcoma virus

1982 • 23 citations

Analysis of the pathogenicity of transformation defective partial deletion mutants of avian sarcoma virus: Characterization of recovered viruses which encode novel src specific proteins

1983 • 19 citations

A mutant of rous sarcoma virus with a thermolabile defect in the virus envelope

1978 • 17 citations

Functional Domains of the pp60^v-src Protein as Revealed by Analysis of Temperature-Sensitive Rous Sarcoma Virus Mutants

1984 • 16 citations

Transformation by the src Oncogene Alters Glucose Transport into Rat and Chicken Cells by Different Mechanisms

1988 • 13 citations

Reversion of Temperature Sensitive Transformation Mutants of Rous Sarcoma Virus and its Effect on the Expression of Tumour Specific Surface Antigen

1978 • 7 citations