Helicobacter pyloriPhysiology Predicted from Genomic Comparison of Two Strains

Bergey's Manual of Determinative Bacteriology

1975 • 11,384 citations

Escherichia coli and Salmonella :cellular and molecular biology

1996 • 8,124 citations

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

1998 • 7,572 citations

The complete genome sequence of the Gram-positive bacterium Bacillus subtilis

1997 • 3,613 citations

The complete genome sequence of the gastric pathogen Helicobacter pylori

1997 • 3,529 citations

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

1999 • 1,904 citations

cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

1996 • 1,883 citations

Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori

1995 • 1,551 citations

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

1997 • 1,417 citations

Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging

1998 • 1,182 citations

Molecular biology of microbial ureases

1995 • 1,167 citations

Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics

1997 • 1,147 citations

Growth of the Stress-Bearing and Shape-Maintaining Murein Sacculus of Escherichia coli

1998 • 1,113 citations

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus

1998 • 1,105 citations

Complete Genome Sequence of Treponema pallidum , the Syphilis Spirochete

1998 • 1,060 citations

Helicobacter pylori

1997 • 1,044 citations

DNA diversity among clinical isolates ofHelicobacter pyloridetected by PCR-based RAPD fingerprinting

1992 • 760 citations

Analyses of the cag pathogenicity island of Helicobacter pylori

1998 • 714 citations

Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets

1991 • 693 citations

Properties of the Penicillin‐Binding Proteins of Escherichia coli K12

1977 • 645 citations

Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori

1998 • 618 citations

SERINE β-LACTAMASES AND PENICILLIN-BINDING PROTEINS

1991 • 610 citations

Direct Binding of FtsZ to ZipA, an Essential Component of the Septal Ring Structure That Mediates Cell Division in E. coli

1997 • 517 citations

Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains.

1994 • 490 citations

Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity

1996 • 427 citations

Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity

1991 • 419 citations

Cell division inhibitors SulA and MinCD prevent formation of the FtsZ ring

1993 • 409 citations

From TCR Engagement to T Cell Activation

1999 • 379 citations

Colonization of gnotobiotic piglets by Helicobacter pylori deficient in two flagellin genes

1996 • 352 citations

Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis

1996 • 339 citations

Agrobacterium tumefaciens T-complex transport apparatus: a paradigm for a new family of multifunctional transporters in eubacteria

1997 • 322 citations

Molecular characterization of an operon required for pertussis toxin secretion.

1993 • 307 citations

Glu-tRNA ^Gln amidotransferase: A novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation

1997 • 304 citations

Genes for a microaerobically induced oxidase complex in Bradyrhizobium japonicum are essential for a nitrogen-fixing endosymbiosis.

1993 • 298 citations

Motility as a factor in the colonisation of gnotobiotic piglets by Helicobacter pylori

1992 • 294 citations

A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach

1994 • 294 citations

Expanding Allelic Diversity of Helicobacter pylori vacA

1998 • 280 citations

Helicobacter Pylori and Gastroduodenal Disease

1992 • 257 citations

PCR-based RFLP analysis of DNA sequence diversity in the gastric pathogenHelicobacter pylori

1992 • 252 citations

Effects of mutations in heat-shock genes groES and groEL on protein export in Escherichia coli.

1989 • 250 citations

Cloning and genetic characterization of the Helicobacter pylori and Helicobacter mustelae flaB flagellin genes and construction of H. pylori flaA- and flaB-negative mutants by electroporation-mediated allelic exchange

1993 • 216 citations

Type III secretion systems: machines to deliver bacterial proteins into eukaryotic cells?

1997 • 213 citations

Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease

1995 • 204 citations

Induction of host signal transduction pathways by Helicobacter pylori

1997 • 202 citations

Unique cholesteryl glucosides in Helicobacter pylori: composition and structural analysis

1995 • 198 citations

Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides

1997 • 194 citations

Lipopolysaccharide of the Helicobacter pylori Type Strain NCTC 11637 (ATCC 43504): Structure of the O Antigen Chain and Core Oligosaccharide Regions

1996 • 192 citations

Characterization of a Pseudomonas aeruginosa gene cluster involved in pilus biosynthesis and twitching motility: sequence similarity to the chemotaxis proteins of enterics and the gliding bacterium Myxococcus xanthus

1994 • 192 citations

Construction of a Helicobacter pylori genome map and demonstration of diversity at the genome level

1992 • 190 citations

Not all Helicobacter pylori strains are created equal: should all be eliminated?

1997 • 186 citations

Cloning and genetic characterization of a Hellcobacter pylori flagellin gene

1992 • 173 citations

Lipopolysaccharides of Helicobacter pylori Strains P466 and MO19: Structures of the O Antigen and Core Oligosaccharide Regions

1996 • 168 citations

Helicobacter pylori nickel‐transport gene nixA: synthesis of catalytically active urease in Escherichia coli independent of growth conditions

1995 • 159 citations

Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori?

1997 • 156 citations

Variability of gene order in different Helicobacter pylori strains contributes to genome diversity

1996 • 156 citations

Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium: characterization of the dipeptide permease (Dpp) and the dipeptide‐binding protein

1991 • 153 citations

Peptidoglycan synthetic activities in membranes of Escherichia coli caused by overproduction of penicillin-binding protein 2 and rodA protein.

1986 • 153 citations

Transient and persistent experimental infection of nonhuman primates with Helicobacter pylori: implications for human disease

1996 • 152 citations

Structural similarity among Escherichia coli FtsW and RodA proteins and Bacillus subtilis SpoVE protein, which function in cell division, cell elongation, and spore formation, respectively

1989 • 151 citations

Iron acquisition by Helicobacter pylori: importance of human lactoferrin

1993 • 146 citations

A novel membrane protein involved in protein translocation across the cytoplasmic membrane of Escherichia coli.

1993 • 143 citations

Determinants of Helicobacter pylori pathogenicity.

1996 • 141 citations

Evidence for Specific Secretion Rather than Autolysis in the Release of Some Helicobacter pylori Proteins

1998 • 141 citations

Purification of Helicobacter pylori superoxide dismutase and cloning and sequencing of the gene

1993 • 140 citations

Helicobacter pylori porCDABandoorDABCGenes Encode Distinct Pyruvate:Flavodoxin and 2-Oxoglutarate:Acceptor Oxidoreductases Which Mediate Electron Transport to NADP

1998 • 138 citations

Genotyping of Helicobacter pylori isolates by sequencing of PCR products and comparison with the RAPD technique

1996 • 137 citations

gltB gene and regulation of nitrogen metabolism by glutamine synthetase in Escherichia coli

1978 • 136 citations

Helicobacter pylori catalase

1991 • 132 citations

Characteristics of Helicobacter pylori growth in a defined medium and determination of its amino acid requirements

1994 • 130 citations

Identification of the Outer Membrane Proteins of Campylobacter pyloridis and Antigenic Cross-reactivity between C. pyloridis and C. jejuni

1987 • 129 citations

Lewis X Biosynthesis in Helicobacter pylori

1997 • 128 citations

Cloning and Heterologous Expression of an α1,3-Fucosyltransferase Gene from the Gastric PathogenHelicobacter pylori

1997 • 126 citations

Molecular mimicry between Helicobacter pylori and the host

1998 • 125 citations

Metabolic activities of metronidazole-sensitive and -resistant strains of Helicobacter pylori: repression of pyruvate oxidoreductase and expression of isocitrate lyase activity correlate with resistance

1996 • 121 citations

Identification of carboxylation enzymes and characterization of a novel four-subunit pyruvate:flavodoxin oxidoreductase from Helicobacter pylori

1995 • 120 citations

Cloning and genetic characterization of Helicobacter pylori catalase and construction of a catalase-deficient mutant strain

1996 • 116 citations

Natural competence for DNA transformation in Helicobacter pylori : identification and genetic characterization of the comB locus

1998 • 115 citations

Lipid profile of Helicobacter spp.: presence of cholesteryl glucoside as a characteristic feature

1996 • 107 citations

Identification of the recR locus of Escherichia coli K-12 and analysis of its role in recombination and DNA repair

1989 • 104 citations

Why does Escherichia coli recycle its cell wall peptides?

1995 • 102 citations

Non‐motile mutants of Helicobacter pylori and Helicobacter mustelae defective in flagellar hook production

1994 • 98 citations

Isolation and characterization of a family of porin proteins from Helicobacter pylori

1995 • 96 citations

Helicobacter pylori ribBA -Mediated Riboflavin Production Is Involved in Iron Acquisition

1998 • 95 citations

Helicobacter pyloriutilises urea for amino acid synthesis

1996 • 94 citations

Hydrogen uptake hydrogenase inHelicobacter pylori

1996 • 94 citations

Defining Helicobacter pylori as a Pathogen: Strain Heterogeneity and Virulence

1996 • 92 citations

Identification of surface-exposed outer membrane antigens of Helicobacter pylori

1994 • 92 citations

Chemotaxis in Bacillus subtilis requires either of two functionally redundant CheW homologs

1994 • 89 citations

Heterogeneity in Levels of Vacuolating Cytotoxin Gene ( vacA ) Transcription among Helicobacter pylori Strains

1998 • 89 citations

Helicobacter pylori Factors Associated With Disease Development

1997 • 88 citations

Mechanisms of TonB-catalyzed iron transport through the enteric bacterial cell envelope

1993 • 87 citations

Dual chemotaxis signaling pathways in Bacillus subtilis: a sigma D-dependent gene encodes a novel protein with both CheW and CheY homologous domains

1994 • 87 citations

The i genome sequence: G genome sequence: Genetic factors for long life in the gastric mucosa

1997 • 82 citations

The role of Helicobacter pylori in pathogenesis: the spectrum of clinical outcomes.

1996 • 82 citations

Helicobacter pylori - a conundrum of genetic diversity

1998 • 82 citations

Novel sequence organization and insertion specificity of IS605 and IS606: chimaeric transposable elements of Helicobacter pylori

1998 • 82 citations

Purification and properties of calf thymus polyadenosine diphosphate ribose polymerase.

1976 • 81 citations

Nutritional requirements for growth of Helicobacter pylori

1994 • 81 citations

Regulation of transcription of cell division genes in the Escherichia coli dcw cluster

1998 • 81 citations

Glucose utilization and lactate production by Helicobacter pylori

1993 • 78 citations

Iron transport in Escherichia coli K-12

1977 • 78 citations

Heterogeneity of Helicobacter pylori

2012 • 78 citations

Aminoacid utilization by Helicobacter pylori

1995 • 73 citations

Urease-independent chemotactic responses of Helicobacter pylori to urea, urease inhibitors, and sodium bicarbonate

1997 • 72 citations

Metabolism of pyruvate and glucose by intact cells of Helicobacter pylori studied by 13C NMR spectroscopy

1994 • 67 citations

Isolation and characterization of a conserved porin protein from Helicobacter pylori

1995 • 66 citations

Characteristics of Helicobacter pylori alcohol dehydrogenase

1993 • 65 citations

Identification of structures containing polyphosphate in Helicobacter pylori

1993 • 60 citations

Role of vacuolating cytotoxin in gastritis due to Helicobacter pylori in gnotobiotic piglets

1997 • 60 citations

Cloning and Characterization of Helicobacter pyloriSuccinyl CoA:Acetoacetate CoA-transferase, a Novel Prokaryotic Member of the CoA-transferase Family

1997 • 56 citations

Amino acid utilisation and deamination of glutamine and asparagine by Helicobacter pylori

1997 • 54 citations

Transcriptional analysis of the divergent cagAB genes encoded by the pathogenicity island of Helicobacter pylori

1997 • 53 citations

Helicobacter pyloriPopulations in Peruvian Patients

1997 • 52 citations

Pyruvate metabolism in Helicobacter pylori

1994 • 50 citations

Fumarate Reductase: A Target for Therapeutic Intervention Against Helicobacter pylori

1995 • 48 citations

Expression of theE. coli nadBGene and Characterization of the Gene Product L-Aspartate Oxidase

1990 • 47 citations

The Role ofHelicobacter pyloriin Pathogenesis: the Spectrum of Clinical Outcomes

1996 • 46 citations

A db-type cytochrome-c oxidase terminates the respiratory chain in Helicobacter pylori

1996 • 45 citations

The Entner-Doudoroff Pathway in Helicobacter pylori

1994 • 44 citations

The respiratory chain ofHelicobacter pylori: identification of cytochromes and the effects of oxygen on cytochrome and menaquinone levels

1996 • 44 citations

Characterization of the hlyB gene and its role in the production of the EI Tor haemolysin of Vibrio choierae O1

1990 • 43 citations

Molecular characterization of a conserved 20-kilodalton membrane-associated lipoprotein antigen of Helicobacter pylori

1994 • 43 citations

Acetaldehyde and Ethanol Production by Helicobacter pylori

1994 • 39 citations

Evidence for a pentose phosphate pathway inHelicobacter pylori

1991 • 39 citations

Capacity of Helicobacter pylori to generate ionic gradients at low pH is similar to that of bacteria which grow under strongly acidic conditions

1996 • 38 citations

Mutants of Klebsiella aerogenes Lacking Glutamate Dehydrogenase

1974 • 38 citations

The Largest Subunits of RNA Polymerase from Gastric Helicobacters Are Tethered

1998 • 37 citations

Bacterial flagellar diversity and significance in pathogenesis

1992 • 37 citations

Helicobacter pylorigeneshpcopAandhpcopPconstitute a cop operon involved in copper export

1996 • 36 citations

Glucose Phosphorylation in Helicobacter pylori

1993 • 36 citations

Essential role of urease in vitro and in vivo Helicobacter pylori colonization study using a wild-type and isogenic urease mutant strain.

1995 • 36 citations

Identification of a 29 kDa flagellar sheath protein in Helicobacter pylori using a murine monoclonal antibody

1995 • 35 citations

An international perspective on anticholinergic therapy

1996 • 34 citations

Sequencing, expression, and genetic characterization of the Helicobacter pylori ftsH gene encoding a protein homologous to members of a novel putative ATPase family

1996 • 33 citations

Fumarate catabolism in Helicobacter pylori.

1993 • 33 citations

The Helicobacter pylori genome is modified at CATG by the product of hpyIM

1997 • 33 citations

Helicobacter pylori cagA status, vacA genotypes and ulcer disease

1998 • 32 citations

Siderophore production and iron-regulated envelope proteins of Helicobacter pylori

1993 • 32 citations

Characterization of the glutamyl-tRNA(Gln)-to-glutaminyl-tRNA(Gln) amidotransferase reaction of Bacillus subtilis

1988 • 32 citations

Helicobacter pylori Glutamine Synthetase Lacks Features Associated with Transcriptional and Posttranslational Regulation

1998 • 32 citations

De novo synthesis of pyrimidine nucleotides by Helicobacter pylori

1994 • 30 citations

Bacterial flagellar diversity and significance in pathogenesis

1992 • 30 citations

Cloning and functional characterization of Helicobacter pylori fumarate reductase operon comprising three structural genes coding for subunits C, A and B

1997 • 28 citations

Kinetics of substrate oxidation by whole cells and cell membranes of

1995 • 27 citations

Characterisation of glucose transport inHelicobacter pylori

1995 • 27 citations

Salvage synthesis of purine nucleotides by Helicobacter pylori

1994 • 26 citations

Alcohol Metabolism inHelicobacter pylori-infected Stomach

1995 • 25 citations

Salmonella typhimurium Mutants with Altered Glutamate Dehydrogenase and Glutamate Synthase Activities

1980 • 24 citations

Flagellin Gene Diversity among Helicobacter pylori Strains and IL-8 Secretion from Gastric Epithelial Cells

1997 • 23 citations

Catalase negative mutants ofHelicobacter pylori

1992 • 23 citations

Colloidal bismuth subcitrate and omeprazole inhibit alcohol dehydrogenase mediated acetaldehyde production by Helicobacter pylori

1992 • 23 citations

Kinetics of substrate oxidation by whole cells and cell membranes ofHelicobacter pylori

1995 • 22 citations

Activity of cefixime against Helicobacter pylori and affinities for the penicillin-binding proteins

1990 • 22 citations

Frequency of vacA Genotypes and Cytotoxin Activity in Helicobacter pylori Associated with Low-Grade Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

1998 • 20 citations

A second type of protein methylation reaction in bacterial chemotaxis.

1987 • 16 citations

Identification of flagellar and associated polypeptides of Helicobacter (formerly Campylobacter) pylori

1990 • 16 citations

Flagellin gene profiling of Helicobacter pylori infecting symptomatic and asymptomatic individuals

1994 • 14 citations

Transjugular intrahepatic portosystemic shunting (TIPS): a shunt is a shunt is a shunt!

1997 • 13 citations

Identification of flagellar and associated polypeptides of Helicobacter (formerly Campylobacter) pylori

1990 • 12 citations

Lipid Analysis of Helicobacter pylori

1993 • 11 citations

Purification and properties of carboxynorspermidine decarboxylase, a novel enzyme involved in norspermidine biosynthesis, from Vibrio alginolyticus

1990 • 11 citations

Diversity among Clinical Isolates of Helicobacter pylori in Korea

1997 • 7 citations

Free amino acids of human gastric juice.

1981 • 7 citations

Electrofusion of protoplasts from Aspergillus nidulans

1989 • 6 citations

Deleted Work

1955 • 0 citations