The Interaction and Colocalization of Sam68 with the Splicing-associated Factor YT521-B in Nuclear Dots Is Regulated by the Src Family Kinase p59^fyn

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

J. Submicrosc. Cytol. Pathol.

2000 • 2,783 citations

‘Touchdown’ PCR to circumvent spurious priming during gene amplification

1991 • 2,630 citations

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformaion of Escherichia coli

1987 • 2,493 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1990 • 1,234 citations

The I.M.A.G.E. Consortium: An Integrated Molecular Analysis of Genomes and Their Expression

1996 • 1,132 citations

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1997 • 905 citations

The superfamily of arginine/serine-rich splicing factors.

1995 • 671 citations

Identification of a New Family of Tissue-Specific Basic Helix-Loop-Helix Proteins with a Two-Hybrid System

1995 • 655 citations

Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.

1992 • 619 citations

Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

1994 • 612 citations

The dynamics of a pre-mRNA splicing factor in living cells

1997 • 604 citations

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.

1996 • 559 citations

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

1997 • 528 citations

Prediction of the Coding Sequences of Unidentified Human Genes. II. The Coding Sequences of 40 New Genes (KIAA0041-KIAA0080) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1

1994 • 500 citations

An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

1994 • 407 citations

The growth hormone-binding protein in rat serum is an alternatively spliced form of the rat growth hormone receptor.

1989 • 399 citations

Co-existence of vinculin and a vinculin-like protein of higher molecular weight in smooth muscle.

1982 • 343 citations

Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel gene product, stem cell factor.

1992 • 306 citations

STAR, a gene family involved in signal transduction and activation of RNA

1997 • 295 citations

The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation

1997 • 264 citations

Inositol 1,4,5-trisphosphate receptors: distinct neuronal and nonneuronal forms derived by alternative splicing differ in phosphorylation.

1991 • 233 citations

Two isoforms of the EP3 receptor with different carboxyl-terminal domains. Identical ligand binding properties and different coupling properties with Gi proteins.

1993 • 214 citations

Association of p62, a Multifunctional SH2- and SH3-Domain-Binding Protein, with src Family Tyrosine Kinases, Grb2, and Phospholipase Cγ-1

1995 • 198 citations

Self-Association of the Single-KH-Domain Family Members Sam68, GRP33, GLD-1, and Qk1: Role of the KH Domain

1997 • 186 citations

Cell Type-Specific Expression of hnRNP Proteins

1995 • 177 citations

Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways.

1995 • 174 citations

SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements

1998 • 173 citations

Alternative Splicing of the Dopamine D2 Receptor Directs Specificity of Coupling to G-proteins

1995 • 172 citations

Mammalian alpha 1- and beta 1-syntrophin bind to the alternative splice-prone region of the dystrophin COOH terminus.

1995 • 164 citations

Specificity and Determinants of Sam68 RNA Binding

1997 • 161 citations

A CTD function linking transcription to splicing

1997 • 160 citations

p62 Association with RNA Is Regulated by Tyrosine Phosphorylation

1995 • 147 citations

Rat cystathionine beta-synthase. Gene organization and alternative splicing.

1992 • 144 citations

Alternative splicing generates two isoforms of the α2 subunit of the inhibitory glycine receptor

1991 • 143 citations

hnRNP G: sequence and characterization of a glycosylated RNA-binding protein

1993 • 141 citations

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases

1997 • 140 citations

Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing

1991 • 138 citations

A splice variant of the neurotrophin receptor trkB with increased specificity for brain-derived neurotrophic factor.

1996 • 137 citations

A human homologue of the Drosophila sex determination factor transformer-2 has conserved splicing regulatory functions.

1996 • 131 citations

Prediction of the Coding Sequences of Unidentified Human Genes. V. The Coding Sequences of 40 New Genes (KIAA0161-KIAA0200) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1

1996 • 117 citations

Alternative Splicing of Human Inducible Nitric-Oxide Synthase mRNA

1996 • 112 citations

A sequence compilation and comparison of exons that are alternatively spliced in neurons

1994 • 105 citations

Alternative splicing and endoproteolytic processing generate tissue-specific forms of pituitary peptidylglycine alpha-amidating monooxygenase (PAM).

1992 • 103 citations

Developmental Role of Transcription Factor Isoforms Generated by Alternative Splicing

1995 • 99 citations

Functional Interaction between c-Src and Its Mitotic Target, Sam 68

1995 • 97 citations

Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis

1999 • 97 citations

Activity‐dependent regulation of alternative splicing patterns in the rat brain

1999 • 94 citations

A naturally occurring soluble isoform of murine Fas generated by alternative splicing.

1995 • 93 citations

A human RNA helicase-like protein, HRH1, facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.

1996 • 92 citations

Human Transformer-2-beta Gene (SFRS10): Complete Nucleotide Sequence, Chromosomal Localization, and Generation of a Tissue-Specific Isoform

1998 • 87 citations

Molecular Cloning of htra2-beta-1 and htra2-beta-2, Two Human Homologs oftra-2Generated by Alternative Splicing

1997 • 76 citations

Alternative Splicing of STY, a Nuclear Dual Specificity Kinase

1995 • 73 citations

The Human Aromatic <scp>l</scp>‐Amino Acid Decarboxylase Gene Can Be Alternatively Spliced To Generate Unique Protein Isoforms

1995 • 67 citations

Cloning of a gene, YT521, for a novel RNA splicing-related protein induced by hypoxia/reoxygenation

1998 • 63 citations

The Cellular Localization of the Murine Serine/Arginine-rich Protein Kinase CLK2 Is Regulated by Serine 141 Autophosphorylation

1998 • 57 citations

Identification of two alternatively spliced transcripts of STEP: a subfamily of brain-enriched protein tyrosine phosphatases

1995 • 56 citations

Insulin-inducible changes in insulin receptor mRNA splice variants.

1994 • 52 citations

Isolation and characterization of the disconnected gene of Drosophila melanogaster.

1991 • 52 citations

A Homolog of Human Transcription Factor NF-X1 Encoded by the Drosophila shuttle Craft Gene Is Required in the Embryonic Central Nervous System

1996 • 48 citations

Complex alternative RNA splicing of epsilon-immunoglobulin transcripts produces mRNAs encoding four potential secreted protein isoforms.

1994 • 44 citations

Multiple Forms of the U2 Small Nuclear Ribonucleoprotein Auxiliary Factor U2AF Subunits Expressed in Higher Plants

1998 • 42 citations

Insulin Regulates Protein Kinase CβII Expression through Enhanced Exon Inclusion in L6 Skeletal Muscle Cells

1998 • 37 citations

A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization.

1994 • 35 citations

Alternative splicing of class Ib majorhistocompatibility complex transcripts in vivo leads to the expression ofsoluble Qa-2 molecules in murine blood.

1994 • 34 citations

The human RD protein is closely related to nuclear RNA-binding proteins and has been highly conserved

1990 • 31 citations

Alternative Splicing Is Responsible for the Presence of Two Tissue Factor mRNA Species in LPS Stimulated Human Monocytes

1992 • 30 citations

KH Domain Integrity Is Required for Wild-Type Localization of Sam68

1998 • 26 citations

A Putative Mammalian RNA Helicase with an Arginine-Serine-rich Domain Colocalizes with a Splicing Factor

1995 • 25 citations

The Carboxyl-terminal Anchorage Domain of the Turkey β1-Adrenergic Receptor Is Encoded by an Alternatively Spliced Exon

1995 • 19 citations

Human U1-70K ribonucleoprotein antigen gene: Organization, nucleotide sequence, and mapping to locus 19q13.3

1990 • 16 citations

Novel alternative splicing predicts a secreted extracellular isoform of the human receptor-like protein tyrosine phosphatase LAR

1996 • 12 citations

Various transcripts are generated from the VCSA1 gene by alternative splicing and poly(A) processing in the rat submandibular gland

1995 • 8 citations

Alternative Splicing of the ret Proto-Oncogene at Intron 4

1994 • 7 citations

Molecular cloning of a novel alternatively spliced nuclear protein

1997 • 5 citations

A mouse repeat sequence conserved in eukaryotic genomes.

1992 • 2 citations