Fatty acids modulate protein kinase C activation in porcine vascular smooth muscle cells independently of their effect on de novo diacylglycerol synthesis

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

1960 • 2,598 citations

Protein kinase C activation and the development of diabetic complications.

1998 • 1,328 citations

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1986 • 999 citations

Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling

1997 • 669 citations

Protein measurement using bicinchoninic acid: elimination of interfering substances

1989 • 667 citations

New insights into the regulation of protein kinase C and novel phorbol ester receptors

1999 • 600 citations

Anchoring proteins for protein kinase C: a means for isozyme selectivity

1998 • 584 citations

Molecular and Functional Characterization of a Novel Mouse Transient Receptor Potential Protein Homologue TRP7

1999 • 451 citations

Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes.

1995 • 345 citations

A synthetic peptide substrate for selective assay of protein kinase C

1990 • 292 citations

Specificity and mechanism of protein kinase C activation by sn-1,2-diacylglycerols.

1986 • 254 citations

Electrospray and tandem mass spectrometric characterization of acylglycerol mixtures that are dissolved in nonpolar solvents

1991 • 237 citations

Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C

1995 • 228 citations

The nature of protein kinase C activation by physically defined phospholipid vesicles and diacylglycerols.

1985 • 228 citations

Fatty acids and cell signal transduction.

1994 • 206 citations

Mitogen-activated protein kinases as glucose transducers for diabetic complications

1999 • 195 citations

Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols.

1976 • 195 citations

Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues

1994 • 186 citations

Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM

1988 • 184 citations

Determination of serum triglycerides by an accurate enzymatic method not affected by free glycerol.

1985 • 158 citations

sn-1,2-Diacylglycerol kinase of Escherichia coli. Mixed micellar analysis of the phospholipid cofactor requirement and divalent cation dependence.

1986 • 148 citations

[17] Structure and lipid binding properties of serum albumin

1986 • 136 citations

Transport and sorting of membrane lipids

1993 • 123 citations

Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia

1994 • 106 citations

A novel protein kinase target for the lipid second messenger phosphatidic acid

1999 • 97 citations

The effects of long chain free fatty acids on human neutrophil function and structure.

1976 • 84 citations

Incubation of exogenous fatty acids with lymphocytes. Changes in fatty acid composition and effects on the rotational relaxation time of 1,6-diphenyl-1,3,5-hexatriene

1980 • 79 citations

Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin

1995 • 79 citations

Protein kinase C isoenzymes in rat and human cardiovascular tissues

1997 • 75 citations

Protein Kinase C-Mediated Inhibition of Vascular Smooth Muscle Cell Proliferation: The Isoforms That May Mediate G1/S Inhibition

1993 • 69 citations

Use of a fluorescent probe to compare the plasma membrane properties in normal and transformed cells. Evaluation of the interference by triacylglycerols and alkyldiacylglycerols

1978 • 68 citations

A myo-inositol pool utilized for phosphatidylinositol synthesis is depleted in sciatic nerve from rats with streptozotocin-induced diabetes.

1990 • 59 citations

Insulin action and non-esterified fatty acids

1997 • 54 citations

Possible Involvement of Phospholipase D and Protein Kinase C in Vascular Growth Induced by Elevated Glucose Concentration

1996 • 51 citations

A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.

1999 • 42 citations

Mechanism of extracellular ATP-induced proliferation of vascular smooth muscle cells.

1996 • 41 citations

[17] Diacylglycerol kinase from escherichia coli

1992 • 36 citations

The role of protein kinase C in activation and termination of mitogen-activated protein kinase activity in angiotensin II-stimulated rat aortic smooth-muscle cells

1996 • 32 citations

Activation of Protein Kinase C in Glomerular Cells in Diabetes: Mechanisms and Potential Links to the Pathogenesis of Diabetic Glomerulopathy

1994 • 21 citations

Differential effects of fatty acids on glycolysis and glycogen metabolism in vascular smooth muscle

1991 • 20 citations

Diacylglycerol directly stimulates the insulin receptor tyrosine kinase

1996 • 17 citations

Down-regulation of glucose transport by elevated extracellular glucose concentrations in cultured rat aortic smooth muscle cells does not normalize intracellular glucose concentrations

1996 • 17 citations

Comparative study of high-glucose effect on phosphatidylcholine hydrolysis of cultured retinal capillary pericytes and endothelial cells

1994 • 10 citations

1,2-diacylglycerol content and its fatty acid composition in thoracic aorta of diabetic rats

1991 • 8 citations

A manual enzymic assay of non-esterified fatty acids adapted to a centrifugal analyzer.

1987 • 2 citations