Selective Inhibition of IL-Gene Expression by 2Trichostatin A, a Potent Inhibitor of Mammalian Histone Deacetylase.

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1964 • 2,410 citations

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

1990 • 1,835 citations

Sodium butyrate inhibits histone deacetylation in cultured cells

1978 • 1,008 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

The effect of sodium butyrate on histone modification

1978 • 680 citations

Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences.

1978 • 459 citations

Different accessibilities in chromatin to histone acetylase.

1979 • 340 citations

A new antifungal antibiotic, trichostatin.

1976 • 319 citations

On the biological role of histone acetylation

1990 • 246 citations

Transcription: In tune with the histones

1994 • 239 citations

Hypericin and pseudohypericin specifically inhibit protein kinase C: Possible relation to their antiretroviral activity

1989 • 221 citations

Trichostatin A Induces Morphological Changes and Gelsolin Expression by Inhibiting Histone Deacetylase in Human Carcinoma Cell Lines

1994 • 193 citations

Reversible arrest of proliferation of rat 3Y1 fibroblasts in both the G1 and G2 phases by trichostatin A

1988 • 192 citations

Effects of trichostatins on differentiation of murine erythroleukemia cells.

1987 • 171 citations

Regulation of c‐myc expression by sodium butyrate in the colon carcinoma cell line Caco‐2

1993 • 68 citations

Trichostatin A inhibits both ras-induced neurite outgrowth of PC12 cells and morphological transformation of NIH3T3 cells.

1995 • 59 citations

Morphological reversion of sis-transformed NIH3T3 cells by trichostatin A.

1992 • 53 citations

Trichostatin C, a glucopyranosyl hydroxamate.

1978 • 42 citations

Relationship between Core Histone Acetylation and Histone H1⁰ Gene Activity

1994 • 41 citations

Activation of the mouse cytokeratin A (endo A) gene in teratocarcinoma F9 cells by the histone deacetylase inhibitor Trichostatin A

1994 • 25 citations

An antigen-specific signal is required for the activation of second-order suppressor T cells in the regulation of delayed-type hypersensitivity to 2,4,6-trinitrobenzene sulfonic acid.

1983 • 22 citations