Regulation of c‐myc expression by sodium butyrate in the colon carcinoma cell line Caco‐2

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Short chain fatty acids in human large intestine, portal, hepatic and venous blood.

1987 • 2,744 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1977 • 1,556 citations

Short chain fatty acids in the human colon.

1981 • 1,037 citations

Effects of sodium butyrate, a new pharmacological agent, on cells in culture

1981 • 808 citations

myc FUNCTION AND REGULATION

1992 • 790 citations

Control of c-myc Regulation in Normal and Neoplastic Cells

1991 • 632 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells.

1985 • 497 citations

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues

1984 • 486 citations

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

1991 • 484 citations

The human colon carcinoma cell lines HT-29 and Caco-2: Two in vitro models for the study of intestinal differentiation

1986 • 470 citations

Two promoters of different strengths control the transcription of the mouse alpha-amylase gene Amy-1a in the parotid gland and the liver

1983 • 469 citations

Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences.

1978 • 459 citations

Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

1983 • 436 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant.

1992 • 301 citations

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors.

1991 • 297 citations

An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA.

1991 • 293 citations

A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

1991 • 268 citations

Polyamines Differentially Modulate the Transcription of Growth-associated Genes in Human Colon Carcinoma Cells

1989 • 211 citations

A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif

1988 • 187 citations

Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex.

1992 • 181 citations

Effects of sodium butyrate on human colonic adenocarcinoma cells. Induction of placental-like alkaline phosphatase.

1987 • 153 citations

Clonal analysis of sucrase-isomaltase expression in the human colon adenocarcinoma Caco-2 cells

1991 • 151 citations

U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3' untranslated region of c-fos mRNA may be involved in the first step of c-fos mRNA degradation.

1992 • 135 citations

Regulation of proto-oncogene mRNA stability

1992 • 111 citations

5'-flanking sequences mediate butyrate stimulation of embryonic globin gene expression in adult erythroid cells.

1991 • 108 citations

Mutational analysis of sodium butyrate inducible elements in the human immunodeficiency virus type I long yerminal repeat

1989 • 64 citations

Translation of c-myc mRNA is required for its post-transcriptional regulation during myogenesis.

1990 • 54 citations

Myc and Max: a putative transcriptional complex in search of a cellular target

1992 • 48 citations

Rapidc-mycmRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA

1991 • 43 citations

AUUUA motifs are dispensable for rapid degradation of the mouse c-myc RNA.

1990 • 42 citations

Evidence for a labile intermediate in the butyrate induced reduction of the level of c-myc RNA in SW837 rectal carcinoma cells.

1988 • 38 citations

Induction of carcinoembryonic-antigen-gene expression in human colorectal carcinoma by sodium butyrate

1990 • 33 citations

Butyrate-induced changes in nuclease sensitivity of chromatin cannot be correlated with transcriptional activation.

1987 • 29 citations