Dysregulation of HSG triggers vascular proliferative disorders

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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

2003 • 2,349 citations

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1994 • 2,154 citations

Mice Lacking p27 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

1996 • 1,583 citations

A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice

1996 • 1,488 citations

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1990 • 1,228 citations

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2001 • 957 citations

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G₁/S-Regulatory Genes

1995 • 910 citations

Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies

2002 • 830 citations

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Requirement of p27 ^Kip1 for Restriction Point Control of the Fibroblast Cell Cycle

1996 • 683 citations

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2000 • 511 citations

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Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F

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Cytostatic Gene Therapy for Vascular Proliferative Disorders with a Constitutively Active form of the Retinoblastoma Gene Product

1995 • 455 citations

Gene Therapy for Vascular Smooth Muscle Cell Proliferation After Arterial Injury

1994 • 443 citations

Ras Links Growth Factor Signaling to the Cell Cycle Machinery via Regulation of Cyclin D1 and the Cdk Inhibitor p27^KIP1

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Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo

1993 • 367 citations

Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty.

1995 • 363 citations

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Recombinant platelet-derived growth factor B gene expression in porcine arteries induce intimal hyperplasia in vivo.

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A Modified Alkaline Lysis Method for the Preparation of Highly Purified Plasmid DNA from Escherichia Coli

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Adenovirus-Mediated Heme Oxygenase-1 Gene Delivery Inhibits Injury-Induced Vascular Neointima Formation

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Drug-Eluting Stents

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1994 • 98 citations

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Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombin

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Overview of therapies for prevention of restenosis after coronary interventions

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Cellular ras activity is required for passage through multiple points of the G0/G1 phase in BALB/c 3T3 cells.

1994 • 68 citations

The p42/p44 Mitogen-activated Protein Kinase Activation Triggers p27Kip1 Degradation Independently of CDK2/Cyclin E in NIH 3T3 Cells

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Effect of percutaneous adenovirus-mediated Gax gene delivery to the arterial wall in double-injured atheromatous stented rabbit iliac arteries

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The Third Intracellular Loop and the Carboxyl Terminus of β₂-Adrenergic Receptor Confer Spontaneous Activity of the Receptor

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The effects of perindopril on vascular smooth muscle polyploidy in stroke-prone spontaneously hypertensive rats

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Break the Cycle: The Role of Cell-Cycle Modulation in the Prevention of Vasculoproliferative Diseases

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Impaired ceramide signalling in spontaneously hypertensive rat vascular smooth muscle: a possible mechanism for augmented cell proliferation

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Novel methods for adenovirus-mediated gene transfer to blood vessels in vivo.

1997 • 22 citations

Cardiovascular disease increasing in developing countries

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