Structural Basis of Membrane Targeting by the Phox Homology Domain of Cytokine-independent Survival Kinase (CISK-PX)

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1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

1997 • 10,943 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

1997 • 1,448 citations

PHOSPHOINOSITIDE KINASES

1998 • 1,321 citations

Structural basis for the binding of proline-rich peptides to SH3 domains

1994 • 1,016 citations

AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation

1999 • 997 citations

[29] Preparation of selenomethionyl proteins for phase determination

1997 • 861 citations

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

2001 • 600 citations

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

1999 • 598 citations

Phosphoinositide Recognition Domains

2003 • 556 citations

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

1999 • 555 citations

PHOSPHOINOSITIDE LIPIDS AS SIGNALING MOLECULES: Common Themes for Signal Transduction, Cytoskeletal Regulation, and Membrane Trafficking

1998 • 515 citations

The role of phosphoinositides in membrane transport

2001 • 482 citations

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

2001 • 402 citations

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

1999 • 396 citations

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes

2001 • 362 citations

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

1996 • 328 citations

Phosphoinositide signaling and the regulation of membrane trafficking in yeast

2000 • 317 citations

Structure of the C2 domain of human factor VIII at 1.5 Å resolution

1999 • 309 citations

Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

2002 • 308 citations

Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3‐kinases: Binding partners of SH3 domains?

1996 • 304 citations

SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

2001 • 278 citations

The Crystal Structure of the PX Domain from p40phox Bound to Phosphatidylinositol 3-Phosphate

2001 • 273 citations

Subcellular targeting by membrane lipids

2001 • 259 citations

Multivalent Endosome Targeting by Homodimeric EEA1

2001 • 248 citations

Location, Location, Location: Membrane Targeting Directed by PX Domains

2001 • 237 citations

The PX domain: a new phosphoinositide-binding module

2002 • 184 citations

Modular phosphoinositide-binding domains – their role in signalling and membrane trafficking

2001 • 179 citations

Phosphatidylinositol 3-Phosphate Recognition by the FYVE Domain

1999 • 170 citations

Structural Mechanism of Endosome Docking by the FYVE Domain

2001 • 168 citations

Solution structure of the PX domain, a target of the SH3 domain.

2001 • 165 citations

AH/PH Domain-Mediated Interaction between Akt Molecules and Its Potential Role in Akt Regulation

1995 • 161 citations

Membrane Binding Mechanisms of the PX Domains of NADPH Oxidase p40 and p47

2003 • 140 citations

Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival

2000 • 135 citations

The Phox homology (PX) domain, a new player in phosphoinositide signalling

2001 • 128 citations

Phosphoinositide-binding domains

2002 • 127 citations

Phox Homology Domains Specifically Bind Phosphatidylinositol Phosphates

2001 • 125 citations

Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides

2001 • 116 citations

The p40 and p47 PX Domains of NADPH Oxidase Target Cell Membranes via Direct and Indirect Recruitment by Phosphoinositides

2002 • 110 citations

Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate

2001 • 92 citations

The Phox homology (PX) domain, a new player in phosphoinositide signalling

2001 • 90 citations

Crystal Structure of the Yeast Phox Homology (PX) Domain Protein Grd19p Complexed to Phosphatidylinositol-3-phosphate

2003 • 67 citations

Solution Structure of the Vam7p PX Domain^,

2002 • 36 citations

Crystallization of the PX domain of cytokine-independent survival kinase (CISK): improvement of crystal quality for X-ray diffraction with sodium malonate

2003 • 6 citations