Activation of CD4+ T cells in the presence of a nondepleting monoclonal antibody to CD4 induces a Th2-type response in vitro.

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

The route of re-circulation of lymphocytes in the rat

1964 • 1,449 citations

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

1988 • 845 citations

Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: Differentiation antigens of rat lymphocytes

1977 • 777 citations

Identification of Ia glycoproteins in rat thymus and purification from rat spleen

1979 • 682 citations

Two subsets of rat T lymphocytes defined with monoclonal antibodies

1980 • 678 citations

Ability of HIV to Promote a T _H 1 to T _H 0 Shift and to Replicate Preferentially in T _H 2 and T _H 0 Cells

1994 • 482 citations

Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection

1992 • 473 citations

Th1 And Th2 Cells: Different Patterns Of Lymphokine Secretion Lead To Different Functional Properties

1989 • 460 citations

Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4

1989 • 372 citations

Interleukin‐4 and interleukin‐10 synergize to inhibit cell‐mediated immunity in vivo

1993 • 341 citations

Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids.

1989 • 339 citations

The Biologic Roles of CD2, CD4, and CD8 in T-Cell Activation

1989 • 301 citations

Genetic variation in the stress response: susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease

1991 • 254 citations

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

1989 • 237 citations

Experimental allergic encephalomyelitis: successful treatment in vivo with a monoclonal antibody that recognizes T helper cells.

1984 • 222 citations

Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4⁺ T cells

1991 • 218 citations

T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation.

1986 • 218 citations

Leucocyte Antigen Facts Book

1997 • 193 citations

The roles of host and donor cells in the rejection of skin allografts by T cell‐deprived rats injected with syngeneic T cells

1982 • 190 citations

A Repopulation Assay For B and T Lymphocyte Stem Cells Employing Radiation Chimaeras

1981 • 158 citations

Phenotypic and functional heterogeneity of CD4+ T cells

1988 • 142 citations

The CD4-gpl20 Interaction and Aids Pathogenesis

1991 • 137 citations

Selective Activation of Th1‐ and Th2‐like Cells in vivo– Response to Human Collagen IV

1991 • 129 citations

Reprogramming the Immune System for Peripheral Tolerance with CD4 and CD8 Monoclonal Antibodies

1992 • 124 citations

Purification of human C3b inactivator by monoclonal-antibody affinity chromatography

1982 • 122 citations

The leucocyte antigen factsbook

1995 • 110 citations

Anti‐CD4 Monoclonal Antibodies in Therapy: Creation of Nonclassical Tolerance in the Adult

1992 • 104 citations

Inhibition of mixed lymphocyte response by monoclonal antibody specific for a rat T lymphocyte subset

1979 • 94 citations

CD4 mAb therapy modulates alloantibody production and intracardiac graft deposition in association with selective inhibition of Th1 lymphokines.

1993 • 76 citations

A NONDEPLETING ANTI-RAT CD4 MONOCLONAL ANTIBODY THAT SUPPRESSES T HELPER 1-LIKE BUT NOT T HELPER 2-LIKE INTRAGRAFT LYMPHOKINE SECRETION INDUCES LONG-TERM SURVIVAL OF RENAL ALLOGRAFTS

1994 • 75 citations

Biochemical and immunological properties of rat recombinant interleukin-2 and interleukin-4.

1992 • 48 citations

The mechanism of inhibition of experimental allergic encephalomyelitis in the rat by monoclonal antibody against CD4

1986 • 46 citations

Treatment of Multiple Sclerosis with Anti-CD4 Monoclonal Antibody

1993 • 41 citations

HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4.

1994 • 39 citations

Cloning of Rat Interleukin-13 (IL-13) cDNA and Analysis of IL-13 Gene Expression in Experimental Glomerulonephritis

1993 • 34 citations

Anti-CD4 therapy in rheumatoid arthritis.

1993 • 19 citations

The Biologic Roles Of CD2, CD4, And CD8 In T-Cell Activation

1989 • 16 citations

Differentiation of encephalitogenic T cells confers resistance to an inhibitory anti-CD4 monoclonal antibody.

1993 • 10 citations

Envelope Glycoproteins of HIV-1 Interfere with T-Cell-Dependent B Cell Differentiation: Role of CD4-MHC Class II Interaction in the Effector Phase of T Cell Help

1994 • 8 citations

The Cd4-gp120 Interaction And Aids Pathogenesis

1991 • 5 citations