Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

1999 • 3,805 citations

Physical Activity and Risk of Cognitive Impairment and Dementia in Elderly Persons

2001 • 1,518 citations

Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism

1998 • 1,504 citations

CREB AND MEMORY

1998 • 1,421 citations

Mini Review

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Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

1993 • 1,302 citations

Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice

1996 • 1,219 citations

CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression

1996 • 1,109 citations

CREB: A Major Mediator of Neuronal Neurotrophin Responses

1997 • 936 citations

Cross Talk between ERK and PKA Is Required for Ca2+ Stimulation of CREB-Dependent Transcription and ERK Nuclear Translocation

1998 • 885 citations

A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning

2002 • 853 citations

Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis.

2002 • 720 citations

Voluntary Exercise Induces a BDNF-Mediated Mechanism That Promotes Neuroplasticity

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Brain-Derived Neurotrophic Factor Induces Long-Term Potentiation in Intact Adult Hippocampus: Requirement for ERK Activation Coupled to CREB and Upregulation ofArcSynthesis

2002 • 638 citations

Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca²⁺ Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons

1995 • 616 citations

Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs

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Synapsins as mediators of BDNF-enhanced neurotransmitter release

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Neurotrophin-evoked rapid excitation through TrkB receptors

1999 • 540 citations

Synapsins as regulators of neurotransmitter release

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Exercise, experience and the aging brain1

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BDNF Enhances Quantal Neurotransmitter Release and Increases the Number of Docked Vesicles at the Active Zones of Hippocampal Excitatory Synapses

2001 • 506 citations

Learning Deficit in BDNF Mutant Mice

1997 • 470 citations

Impairments in High-Frequency Transmission, Synaptic Vesicle Docking, and Synaptic Protein Distribution in the Hippocampus of BDNF Knockout Mice

1999 • 463 citations

CREB Couples Neurotrophin Signals to Survival Messages

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Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members

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Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N -methyl- <scp>d</scp> -aspartic acid receptor activity

1998 • 406 citations

NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults

1994 • 402 citations

Regular exercise improves cognitive function and decreases oxidative damage in rat brain

2001 • 376 citations

Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity

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A Phospho-Switch Controls the Dynamic Association of Synapsins with Synaptic Vesicles

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Phosphorylation of cAMP Response Element-Binding Protein in Hippocampal Neurons as a Protective Response after Exposure to GlutamateIn Vitroand IschemiaIn Vivo

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Quantitative changes in the synaptic vesicle proteins synapsin I and p38 and the astrocyte-specific protein glial fibrillary acidic protein are associated with chemical-induced injury to the rat central nervous system

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Neurotrophins promote maturation of developing neuromuscular synapses

1995 • 249 citations

Neuroprotective signaling and the aging brain: take away my food and let me run11Published on the World Wide Web on 24 August 2000.

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Brain-Derived Neurotrophic Factor Differentially Regulates Excitatory and Inhibitory Synaptic Transmission in Hippocampal Cultures

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Enhanced NO Inactivation and Hypertension Induced by a High-Fat, Refined-Carbohydrate Diet

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Molecular mechanisms underlying activity-dependent regulation of BDNF expression

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Brain-derived neurotrophic factor: subcellular compartmentalization and interneuronal transfer as visualized with anti-peptide antibodies.

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Cognitive impairment in rats fed high-fat diets: A specific effect of saturated fatty-acid intake.

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Cognitive impairment in rats fed high-fat diets: A specific effect of saturated fatty-acid intake.

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Neurotrophin-induced modulation of synaptic transmission in the adult hippocampus

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Spatial learning induces neurotrophin receptor and synapsin I in the hippocampus

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The effects of high fat diets and environmental influences on cognitive performance in rats

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Calmodulin priming: Nuclear translocation of a calmodulin complex and the memory of prior neuronal activity

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Long-Term Enhancement of Central Synaptic Transmission by Chronic Brain-Derived Neurotrophic Factor Treatment

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Regulation of gene expression and its role in long-term memory and synaptic plasticity

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Effects of a high-fat, sucrose diet on serum insulin and related atherosclerotic risk factors in rats

1993 • 77 citations