Aspirin enhances thermotolerance in human erythroleukemic cells: an effect associated with the modulation of the heat shock response.

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.

1993 • 879 citations

Stress proteins in biology and medicine

1990 • 731 citations

Stress protein systems of mammalian cells

1986 • 564 citations

Effect of Sodium Salicylate on the Human Heat Shock Response

1992 • 411 citations

Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.

1988 • 407 citations

Characterization of the thermotolerant cell. I. Effects on protein synthesis activity and the regulation of heat-shock protein 70 expression.

1988 • 399 citations

Induction of sequence-specific binding of Drosophila heat shock activator protein without protein synthesis

1987 • 382 citations

Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity.

1992 • 376 citations

Activation of Heat Shock Factor 2 during Hemin-Induced Differentiation of Human Erythroleukemia Cells

1992 • 281 citations

Rapid expression of heat shock protein in the rabbit after brief cardiac ischemia.

1991 • 265 citations

Posttranscriptional regulation of hsp70 expression in human cells: effects of heat shock, inhibition of protein synthesis, and adenovirus infection on translation and mRNA stability.

1987 • 248 citations

Response of human breast cancer cells to heat shock and chemotherapeutic drugs.

1992 • 247 citations

Heat shock proteins in thermotolerance and other cellular processes.

1987 • 220 citations

Heat Shock RNA Levels in Brain and Other Tissues After Hyperthermia and Transient Ischemia

1990 • 199 citations

Attenuation of the heat shock response in HeLa cells is mediated by the release of bound heat shock transcription factor and is modulated by changes in growth and in heat shock temperatures.

1991 • 197 citations

Arachidonate is a potent modulator of human heat shock gene transcription.

1994 • 192 citations

Discordant expression of heat shock protein mRNAs in tissues of heat-stressed rats.

1990 • 186 citations

Antiproliferative prostaglandins activate heat shock transcription factor.

1992 • 183 citations

Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells.

1989 • 173 citations

Heat shock-induced interactions of heat shock transcription factor and the human hsp70 promoter examined by in vivo footprinting.

1991 • 159 citations

Human heat shock protein 70 (hsp70) protects murine cells from injury during metabolic stress.

1993 • 157 citations

Myocardial protection after whole body heat stress in the rabbit is dependent on metabolic substrate and is related to the amount of the inducible 70-kD heat stress protein.

1994 • 120 citations

Heat shock-induced translational control of HSP70 and globin synthesis in chicken reticulocytes.

1984 • 116 citations

Regulation of Ras-GAP and the Neurofibromatosis-1 Gene Product by Eicosanoids

1991 • 100 citations

Heat shock protein in mammalian brain and other organs after a physiologically relevant increase in body temperature induced by D-lysergic acid diethylamide.

1983 • 98 citations

Heat shock proteins and virus replication: hsp70s as mediators of the antiviral effects of prostaglandins

1994 • 76 citations

Heat shock stimulates the release of arachidonic acid and the synthesis of prostaglandins and leukotriene B₄ in mammalian cells

1989 • 70 citations

Stereotaxic injection of kainic acid into the striatum of rats induces synthesis of mRNA for heat shock protein 70

1988 • 63 citations

Selective inhibition of virus protein synthesis by prostaglandin A1: a translational block associated with HSP70 synthesis

1994 • 59 citations

Effects of Amphetamine on Protein Synthesis and Energy Metabolism in Mouse Brain: Role of Drug‐Induced Hyperthermia

1988 • 47 citations

Induction of Thermotolerance by Prostaglandin A in Human Cells

1993 • 43 citations

Heat sensitivity, thermotolerance, and profile of heat shock protein synthesis of human myelogenous leukemias.

1989 • 23 citations

Induction of HSP70 by Prostaglandins

1990 • 23 citations

Heat sensitivity, thermotolerance, and profile of protein synthesis of human bone marrow progenitors.

1988 • 18 citations

Induction of prostaglandin production by hyperthermia in murine peritoneal exudate macrophages.

1987 • 9 citations