Transcriptional Repression of Human Hepatitis B Virus Genes by a bZIP Family Member, E4BP4

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

1992 • 1,156 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ

1995 • 692 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to CEBP

1990 • 637 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

High-level hepatitis B virus replication in transgenic mice

1995 • 625 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

1990 • 599 citations

Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction.

1993 • 530 citations

Transcriptional repression of eukaryotic promoters

1989 • 481 citations

Distinct Mechanisms for Regulation of the Interleukin-8 Gene Involve Synergism and Cooperativity between C/EBP and NF-κB

1993 • 400 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6.

1992 • 327 citations

The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor.

1992 • 324 citations

Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization

1991 • 312 citations

Active repression mechanisms of eukaryotic transcription repressors

1996 • 308 citations

Stress-Induced Binding of the Transcription Factor CHOP to a Novel DNA Control Element

1996 • 305 citations

Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family.

1990 • 274 citations

Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP.

1990 • 272 citations

C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements.

1993 • 272 citations

A Nuclear Factor for Interleukin-6 Expression (NF-IL6) and the Glucocorticoid Receptor Synergistically Activate Transcription of the Rat α1-Acid Glycoprotein Gene via Direct Protein-Protein Interaction

1993 • 215 citations

Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6.

1996 • 213 citations

Transcriptional repression in eukaryotes

1990 • 210 citations

Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.

1994 • 207 citations

Expression and replication of hepatitis B virus genome in transgenic mice.

1989 • 196 citations

Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus

1992 • 196 citations

The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.

1993 • 195 citations

Transcriptional repression by a novel member of the bZIP family of transcription factors.

1992 • 182 citations

Transcriptional repression in development

1996 • 176 citations

Members of the nuclear receptor superfamily regulate transcription from the hepatitis B virus nucleocapsid promoter

1997 • 164 citations

Short-range repression permits multiple enhancers to function autonomously within a complex promoter.

1994 • 159 citations

CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells.

1995 • 157 citations

Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene.

1994 • 156 citations

Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes

1997 • 140 citations

Replication and gene expression of hepatitis B virus in a transgenic mouse that contains the complete viral genome

1988 • 136 citations

The Ability of C/EBPβ but Not C/EBPα To Synergize with an Sp1 Protein Is Specified by the Leucine Zipper and Activation Domain

1997 • 130 citations

Molecular Cloning and Characterization of NF-IL3A, a Transcriptional Activator of the Human Interleukin-3 Promoter

1995 • 129 citations

Transcriptional Repression in Eukaryotes

1993 • 118 citations

A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP beta and an Sp1 factor.

1994 • 117 citations

The genome of hepatitis B virus contains a second enhancer: cooperation of two elements within this enhancer is required for its function

1990 • 114 citations

Physical and Functional Association between GADD153 and CCAAT/Enhancer-binding Protein β during Cellular Stress

1996 • 113 citations

Functional and Physical Associations between NF-κB and C/EBP Family Members: a Rel Domain-bZIP Interaction

1993 • 112 citations

Functional interaction of nuclear factors EF-C, HNF-4, and RXR alpha with hepatitis B virus enhancer I

1993 • 106 citations

Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription.

1994 • 93 citations

Hepatocyte-Specific Expression of the Hepatitis B Virus Core Promoter Depends on Both Positive and Negative Regulation

1993 • 89 citations

Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domain

1994 • 88 citations

A novel C/EBP beta-YY1 complex controls the cell-type-specific activity of the human papillomavirus type 18 upstream regulatory region

1996 • 82 citations

NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1.

1994 • 82 citations

The ubiquitous transcription factor Oct-1 and the liver-specific factor HNF-1 are both required to activate transcription of a hepatitis B virus promoter.

1991 • 77 citations

Molecular Cloning of a Transcription Factor, AGP/EBP, That Belongs to Members of the C/EBP Family

1990 • 76 citations

Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region

1994 • 68 citations

HNF3 Binds and Activates the Second Enhancer, ENII, of Hepatitis B Virus

1995 • 68 citations

Promoter-specific transactivation of hepatitis B virus transcription by a glutamine- and proline-rich domain of hepatocyte nuclear factor 1

1991 • 66 citations

A liver-specific nuclear factor interacts with the promoter region of the large surface protein gene of human hepatitis B virus.

1989 • 64 citations

Characterization of a Functional Hepatocyte Nuclear Factor 3 Binding Site in the Hepatitis B Virus Nucleocapsid Promoter

1995 • 61 citations

Regulation of Hepatitis B Virus ENI Enhancer Activity by Hepatocyte-Enriched Transcription Factor HNF3

1994 • 61 citations

Regulation of transcription from the hepatitis B virus large surface antigen promoter by hepatocyte nuclear factor 3

1995 • 60 citations

Hepatitis B Virus Enhancer Binds and Is Activated by the Hepatocyte Nuclear Factor 3

1995 • 59 citations

C/EBP-like proteins binding to the functional box-alpha and box-beta of the second enhancer of hepatitis B virus.

1991 • 52 citations

Identification of a C/EBP-Rel Complex in Avian Lymphoid Cells

1994 • 45 citations

Differentiated liver cell specificity of the second enhancer of hepatitis B virus

1993 • 45 citations

The surface gene promoter of the human hepatitis B virus displays a preference for differentiated hepatocytes

1989 • 43 citations

Commentary negative regulation of eukaryotic transcription

1991 • 39 citations

Repression of enhancer II activity by a negative regulatory element in the hepatitis B virus genome

1994 • 39 citations

Protein-protein interaction between the transcriptional repressor E4BP4 and the TBP-binding protein Dr1

1996 • 37 citations

The Ubiquitous Transcription Factor Oct-1 and the Liver-Specific Factor HNF-1 Are Both Required to Activate Transcription of a Hepatitis B Virus Promoter

1991 • 32 citations

Transcriptional Repression by a Novel Member of the bZIP Family of Transcription Factors

1992 • 29 citations

Competition for a Unique Response Element Mediates Retinoic Acid Inhibition of Vitamin D3-stimulated Transcription

1996 • 25 citations

Transcription Factors NF-IL6 and CREB Recognize a Common Essential Site in the Human Prointerleukin 1β Gene

1994 • 25 citations

Characterization of human E4BP4, a phosphorylated bZIP factor

1995 • 23 citations

C/EBP-Like Proteins Binding to the Functional Box-α and Box-β of the Second Enhancer of Hepatitis B Virus

1991 • 22 citations

A Liver-Specific Nuclear Factor Interacts with the Promoter Region of the Large Surface Protein Gene of Human Hepatitis B Virus

1989 • 20 citations

NF-IL6 and AP-1 Cooperatively Modulate the Activation of the TSG-6 Gene by Tumor Necrosis Factor Alpha and Interleukin-1

1994 • 19 citations

A Novel cis-Acting Element Controlling the Rat CYP2D5 Gene and Requiring Cooperativity Between C/EBPβ and an Sp1 Factor

1994 • 17 citations

[39] Specific recognition site probes for isolating genes encoding DNA-binding proteins

1993 • 11 citations

Specific Recognition Site Probes for Isolating Genes Encoding DNA-Binding Proteins

1995 • 3 citations