Back to search

A d-Peptide Analog of the Second Extracellular Loop of Claudin-3 and -4 Leads to MisLocalized Claudin and Cellular Apoptosis in Mammary Epithelial Cells

Data up to Jan 2025

Published2010
Citations29
References44

Total Citations Per Year

Abstract

References (44)

Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

1998 • 2,005 citations

Structure and Function of Intercellular Junctions

1974 • 1,339 citations

Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry

2007 • 1,182 citations

A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts

1998 • 923 citations

Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

2009 • 901 citations

Manner of Interaction of Heterogeneous Claudin Species within and between Tight Junction Strands

1999 • 724 citations

Regulation of tight junctions during the epithelium-mesenchyme transition:direct repression of the gene expression of claudins/occludin by Snail

2003 • 635 citations

Origins and virulence mechanisms of uropathogenic Escherichia coli

2008 • 580 citations

Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions

1998 • 532 citations

Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut

2001 • 532 citations

A Synthetic Peptide Corresponding to the Extracellular Domain of Occludin Perturbs the Tight Junction Permeability Barrier

1997 • 527 citations

Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells

2005 • 451 citations

Loss of tight junction barrier function and its role in cancer metastasis

2008 • 443 citations

Formation of tight junction: determinants of homophilic interaction between classic claudins

2007 • 371 citations

Tight Junction Proteins Claudin-1 and Occludin Control Hepatitis C Virus Entry and Are Downregulated during Infection To Prevent Superinfection

2008 • 340 citations

Interferon‐γ induces internalization of epithelial tight junction proteins via a macropinocytosis‐like process

2005 • 340 citations

The Molecular Physiology of Tight Junction Pores

2004 • 300 citations

Tight Junction–associated MARVEL Proteins MarvelD3, Tricellulin, and Occludin Have Distinct but Overlapping Functions

2010 • 294 citations

Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer.

2003 • 292 citations

Role of claudin interactions in airway tight junctional permeability

2003 • 283 citations

Clostridium perfringens Enterotoxin Elicits Rapid and Specific Cytolysis of Breast Carcinoma Cells Mediated through Tight Junction Proteins Claudin 3 and 4

2004 • 249 citations

Combining serial analysis of gene expression and array technologies to identify genes differentially expressed in breast cancer.

1999 • 241 citations

Effect of d-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide

1999 • 234 citations

Coxsackievirus Entry across Epithelial Tight Junctions Requires Occludin and the Small GTPases Rab34 and Rab5

2007 • 221 citations

Antimicrobial Activity and Stability to Proteolysis of Small Linear Cationic Peptides with D‐Amino Acid Substitutions

2002 • 213 citations

D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasms

2010 • 203 citations

Disruption of Tight Junctions and Induction of Proinflammatory Cytokine Responses in Colonic Epithelial Cells by Campylobacter jejuni

2006 • 189 citations

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family

2009 • 178 citations

The specific fates of tight junction proteins in apoptotic epithelial cells

2004 • 165 citations

Regulation of Heterotypic Claudin Compatibility

2007 • 150 citations

On the self-association potential of transmembrane tight junction proteins

2006 • 124 citations

Comparison of Biophysical and Biologic Properties of α‐Helical Enantiomeric Antimicrobial Peptides

2006 • 119 citations

Claudin 4 identifies a wide spectrum of epithelial neoplasms and represents a very useful marker for carcinoma versus mesothelioma diagnosis in pleural and peritoneal biopsies and effusions

2007 • 114 citations

Permeability of human HT‐29/B6 colonic epithelium as a function of apoptosis

2001 • 108 citations

Structure and Function of Extracellular Claudin Domains

2009 • 106 citations

Differential expression of claudin tight junction proteins in the human cortical nephron

2010 • 82 citations

Subcellular fractionation of polarized epithelial cells and identification of organelle‐specific proteins by two‐dimensional gel electrophoresis

1997 • 75 citations

Perturbation of the tight junction permeability barrier by occludin loop peptides activates β‐catenin/TCF/LEF‐mediated transcription

2001 • 57 citations

Differential Expression of Claudin 1, 3, and 4 During Normal Mammary Gland Development in the Mouse

2006 • 47 citations

Preparative reversed-phase high-performance liquid chromatography collection efficiency for an antimicrobial peptide on columns of varying diameters (1mm to 9.4mm I.D.)

2006 • 46 citations

All-D-cecropin B: synthesis, conformation, lipopolysaccharide binding, and antibacterial activity.

2001 • 45 citations

Claudin-7 expression in human epithelial ovarian cancer

2008 • 43 citations

Disruption of occludin function in polarized epithelial cells activates the extrinsic pathway of apoptosis leading to cell extrusion without loss of transepithelial resistance

2009 • 38 citations

Evidence that Membrane Rafts Are Not Required for the Action of Clostridium perfringens Enterotoxin

2008 • 17 citations

Cited By (0)

Loading...