Serotonin transporter polymorphism and response to SSRIs in major depression and relevance to anxiety disorders and substance abuse

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States

1994 • 12,456 citations

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

1996 • 5,154 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

Allelic Variation of Human Serotonin Transporter Gene Expression

1996 • 2,225 citations

Sex and depression in the National Comorbidity Survey I: Lifetime prevalence, chronicity and recurrence

1993 • 2,168 citations

Sex Differences and the Epidemiology of Depression

1977 • 1,847 citations

One-Month Prevalence of Mental Disorders in the United States

1988 • 1,755 citations

Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

1989 • 1,360 citations

Kaplan and Sadock's Synopsis of Psychiatry: Behavioral Sciences Clinical Psychiatry

1994 • 1,037 citations

Neurobiology of the Caenorhabditis elegans Genome

1998 • 912 citations

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

1993 • 883 citations

A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders.

1996 • 667 citations

Drug target validation and identification of secondary drug target effects using DNA microarrays

1998 • 663 citations

Organization of the human serotonin transporter gene

1994 • 623 citations

The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants

2000 • 622 citations

Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine

1998 • 605 citations

Prevalence and Correlates of Drug Use and Dependence in the United States

1995 • 490 citations

Sex and depression in the national comorbidity survey. II: Cohort effects

1994 • 469 citations

A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity

2000 • 468 citations

Evidence of linkage between the serotonin transporter and autistic disorder

1997 • 435 citations

Molecular Physiology of Norepinephrine and Serotonin Transporters

1994 • 404 citations

Serotonin transporter gene polymorphism and antidepressant response

2000 • 392 citations

Cocaine, Ethanol, and Genotype Effects on Human Midbrain Serotonin Transporter Binding Sites and mRNA Levels

1998 • 390 citations

Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder

1997 • 305 citations

Pharmacogenetics and pharmacogenomics: why is this relevant to the clinical geneticist?

1999 • 267 citations

Serotonin transporter (5-HTT) gene variants associated with autism?

1997 • 260 citations

Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior

1999 • 249 citations

Role of the Serotonin Transporter Promoter Polymorphism in Anxiety-Related Traits

1998 • 248 citations

Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders

1998 • 248 citations

Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder

1998 • 205 citations

Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder

1999 • 192 citations

How Common Is Resistance to Treatment in Recurrent, Nonpsychotic Geriatric Depression?

1998 • 187 citations

Association of unipolar major depressive disorder with genes of the serotonergic and dopaminergic pathways

1999 • 181 citations

Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1,4,5) trisphosphate

1999 • 173 citations

Serotonin transporter (5-HTT) and ?-aminobutyric acid receptor subunit ?3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families

1999 • 158 citations

Association Analysis of a Regulatory Variation of the Serotonin Transporter Gene with Severe Alcohol Dependence

1997 • 153 citations

Serotonin Transporter and Seasonal Variation in Blood Serotonin in Families with Obsessive-Compulsive Disorder

1998 • 152 citations

The hidden patient: unrecognized panic disorder.

1990 • 151 citations

Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT)

1997 • 150 citations

Genetic Variation as a Guide to Drug Development

1998 • 143 citations

Brief research communication: serotonin transporter (5-HTT) gene polymorphisms are not associated with susceptibility to mood disorders

1998 • 126 citations

Association between obsessive-compulsive disorder and polymorphisms of genes encoding components of the serotonergic and dopaminergic pathways

2000 • 118 citations

Altered Allelic Distributions of the Serotonin Transporter Gene in Migraine Without Aura and Migraine with Aura

1998 • 107 citations

Neurotransmitter Transporters: Molecular Biology, Function, and Regulation

1995 • 101 citations

Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimerʼs disease

1997 • 100 citations

Binding of some antidepressants to the 5-hydroxytryptamine transporter in brain and platelets

1990 • 96 citations

Serotonin Receptor Subtypes: Implications for Psychopharmacology

1991 • 96 citations

Advances in sodium-ion coupled biogenic amine transporters

1992 • 65 citations

The short variant of the polymorphism within the promoter region of the serotonin transporter gene is a risk factor for late onset Alzheimer's disease

1998 • 62 citations

How Do Antidepressants Work? Prospects for Genetic Analysis of Drug Mechanisms

1999 • 59 citations

A novel allele in the promoter region of the human serotonin transporter gene

1999 • 56 citations

Lithium in Tricyclic-Resistant Depression Correlation of Increased Brain 5-HT Function with Clinical Outcome

1991 • 51 citations

Bipolar disorder and the serotonin transporter gene: a family-based association study

1999 • 43 citations

The Holocaust and German Psychiatry

1991 • 36 citations

Serotonin receptor and reuptake sites: pharmacologic significance.

1990 • 31 citations

New views of biogenic amine transporter function: implications for neuropsychopharmacology

1999 • 29 citations

Pharmacogenetics: Promise and Potential in Child and Adolescent Psychiatry

2000 • 23 citations

Analysis and meta‐analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders

1998 • 14 citations