Role of the cdc25C phosphatase in G2 arrest induced by nitrogen mustard.

Checkpoints: Controls That Ensure the Order of Cell Cycle Events

1989 • 3,036 citations

Cyclin A is required at two points in the human cell cycle.

1992 • 1,380 citations

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

1994 • 759 citations

Cyclin activation of p34cdc2

1990 • 690 citations

mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2

1991 • 688 citations

Creative blocks: cell-cycle checkpoints and feedback controls

1992 • 686 citations

Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis.

1993 • 675 citations

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.

1991 • 502 citations

Fission yeast chkl protein kinase links the rad checkpoint pathway to cdc2

1993 • 464 citations

Fission yeast genes involved in coupling mitosis to completion of DNA replication.

1992 • 382 citations

Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2.

1990 • 352 citations

cdc2 phosphorylation is required for its interaction with cyclin.

1991 • 338 citations

CAK, the p34cdc2 activating kinase, contains a protein identical or closely related to p40MO15.

1993 • 326 citations

Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines.

1993 • 309 citations

Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells.

1990 • 280 citations

The cdc25 M-phase inducer: An unconventional protein phosphatase

1992 • 266 citations

p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

1991 • 235 citations

Checkpoint controls in Schizosaccharomyces pombe: rad1.

1992 • 224 citations

Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts.

1993 • 186 citations

G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.

1993 • 162 citations

Relationships between cdc2 kinase, DNA cross-linking, and cell cycle perturbations induced by nitrogen mustard.

1992 • 96 citations

A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells

1992 • 72 citations

Chromosome condensation caused by loss of RCC1 function requires the cdc25C protein that is located in the cytoplasm.

1992 • 71 citations

Differences in Mitotic Control among Mammalian Cells

1991 • 62 citations

Multiple roles for protein phosphatase 1 in regulating the Xenopus early embryonic cell cycle.

1992 • 57 citations

A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells?

1992 • 28 citations

Human Cell Division: The Involvement of Cyclins A and B1, and Multiple cdc2s

1991 • 26 citations