The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP binding.

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

The structure of an antigenic determinant in a protein

1984 • 841 citations

PRE-mRNA SPLICING

1986 • 673 citations

A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly

1988 • 535 citations

Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes

1987 • 530 citations

Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm

1989 • 417 citations

Spliceosome assembly in yeast.

1987 • 402 citations

Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing

1989 • 391 citations

Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor.

1989 • 375 citations

A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5′ cleavage site.

1988 • 364 citations

Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae.

1989 • 340 citations

Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes

1986 • 283 citations

An ordered pathway of snRNP binding during mammalian pre-mRNA splicing complex assembly.

1987 • 272 citations

An Early Hierarchic Role of U1 Small Nuclear Ribonucleoprotein in Spliceosome Assembly

1988 • 271 citations

The NUP1 gene encodes an essential component of the yeast nuclear pore complex

1990 • 219 citations

The effect of temperature-sensitive RNA mutants on the transcription products from cloned ribosomal protein genes of yeast

1981 • 206 citations

Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein.

1988 • 188 citations

Identification of ten genes that control ribosome formation in yeast

1970 • 182 citations

Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions

1987 • 180 citations

Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro

1985 • 172 citations

Nuclear pre‐mRNA splicing in yeast

1989 • 156 citations

Early commitment of yeast pre-mRNA to the spliceosome pathway.

1988 • 143 citations

The yeast RNA gene products are essential for mRNA splicing in vitro

1986 • 138 citations

PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle.

1989 • 131 citations

S. cerevisiae U1 RNA is large and has limited primary sequence homology to metazoan U1 snRNA

1987 • 131 citations

RNA11 protein is associated with the yeast spliceosome and is localized in the periphery of the cell nucleus.

1988 • 102 citations

PRP4 (RNA4) from Saccharomyces cerevisiae: Its Gene Product Is Associated with the U4/U6 Small Nuclear Ribonucleoprotein Particle

1989 • 98 citations

The molecular characterization of PRP6 and PRP9 yeast genes reveals a new cysteine/histidine motif common to several splicing factors.

1990 • 84 citations

Early Commitment of Yeast Pre-mRNA to the Spliceosome Pathway

1988 • 75 citations

Different Small Nuclear Ribonucleoprotein Particles Are Involved in Different Steps of Splicing Complex Formation

1987 • 68 citations

PRP4: a Protein of the Yeast U4/U6 Small Nuclear Ribonucleoprotein Particle

1989 • 62 citations

A novel role for the 3' region of introns in pre-mRNA splicing of Saccharomyces cerevisiae.

1987 • 62 citations

PRP4 (RNA4) from Saccharomyces cerevisiae: its gene product is associated with the U4/U6 small nuclear ribonucleoprotein particle.

1989 • 53 citations

The PRP4 (RNA4) protein of Saccharomyces cerevisiae is associated with the 5' portion of the U4 small nuclear RNA.

1990 • 51 citations

RNA11 Protein is Associated with the Yeast Spliceosome and is Localized in the Periphery of the Cell Nucleus

1988 • 45 citations