Cutting Edge: Signals from the B Lymphocyte Antigen Receptor Regulate MHC Class II Containing Late Endosomes

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Assembly, Transport, and Function of MHC Class II Molecules

1994 • 791 citations

CAPTURE AND PROCESSING OF EXOGENOUS ANTIGENS FOR PRESENTATION ON MHC MOLECULES

1997 • 779 citations

Fine Structure Immunocytochemistry

1993 • 707 citations

T CELL ANTIGEN RECEPTOR SIGNAL TRANSDUCTION PATHWAYS

1996 • 692 citations

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1991 • 663 citations

How B and T cells talk to each other

1994 • 659 citations

Identification of two lysosomal membrane glycoproteins.

1985 • 475 citations

INITIATION AND PROCESSING OF SIGNALS FROM THE B CELL ANTIGEN RECEPTOR

1997 • 440 citations

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

1994 • 349 citations

Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor

1990 • 346 citations

The complexity of signaling pathways activated by the BCR

1997 • 333 citations

Molecular Mechanisms of Transmembrane Signaling in B Lymphocytes

1987 • 279 citations

Syk Protein-tyrosine Kinase Is Regulated by Tyrosine-phosphorylated Iga/Ig/3 Immunoreceptor Tyrosine Activation Motif Binding and Autophosphorylation

1995 • 270 citations

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling.

1995 • 264 citations

The B-cell antigen receptor complex: structure and signal transduction

1994 • 204 citations

Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments

1995 • 198 citations

PI 3-kinase: a pivotal pathway in T-cell activation?

1996 • 188 citations

Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions.

1994 • 168 citations

Characterization of the cation-independent mannose 6-phosphate receptor-enriched prelysosomal compartment in NRK cells

1990 • 161 citations

Major histocompatibility complex-restricted, polyclonal B cell responses resulting from helper T cell recognition of antiimmunoglobulin presented by small B lymphocytes.

1985 • 154 citations

Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity.

1994 • 135 citations

HLA-DM Is Localized to Conventional and Unconventional MHC Class II–Containing Endocytic Compartments

1996 • 122 citations

Different phenotypic variants of the mouse B cell tumor A20/2J are selected by antigen- and mitogen-triggered cytotoxicity of L3T4-positive, I-A-restricted T cell clones.

1986 • 121 citations

Intracellular assembly and transport of endogenous peptide-MHC class II complexes

1994 • 111 citations

Regulation of B-cell commitment to plasma cells or to memory B cells

1997 • 102 citations

Receptor-mediated B cell antigen processing. Increased antigenicity of a globular protein covalently coupled to antibodies specific for B cell surface structures.

1988 • 100 citations

Exposure of K562 cells to anti-receptor monoclonal antibody OKT9 results in rapid redistribution and enhanced degradation of the transferrin receptor.

1986 • 97 citations

Entry of B cell antigen receptor and antigen into class II peptide-loading compartment is independent of receptor cross-linking.

1995 • 83 citations

Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules

1997 • 62 citations

Diminished antigen processing by endosomal acidification mutant antigen-presenting cells.

1989 • 50 citations

B cell antigen receptor signalling links biochemical changes in the class II peptide-loading compartment to enhanced processing

1996 • 36 citations

The B cell antigen receptor complex: Mechanisms and implications of tyrosine kinase activation

1994 • 13 citations