DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I.

The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen

1993 • 1,219 citations

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

1990 • 677 citations

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1994 • 637 citations

Mechanism of interaction between Ku protein and DNA.

1986 • 485 citations

The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1

1992 • 427 citations

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.

1990 • 415 citations

DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair.

1995 • 342 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.

1993 • 311 citations

Rate-limiting steps in RNA chain initiation.

1980 • 308 citations

A DNA-activated protein kinase from HeLa cell nuclei.

1990 • 285 citations

HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex

1989 • 273 citations

Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant.

1994 • 238 citations

Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks.

1994 • 215 citations

Molecular Cloning of cDNA Encoding the p70 (Ku) Lupus Autoantigen

1989 • 212 citations

Analysis of the mechanism of interaction of simian Ku protein with DNA

1991 • 207 citations

The nuclear serine/threonine protein kinase DNA-PK.

1992 • 192 citations

Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II

1993 • 184 citations

Purification and analysis of RNA polymerase II transcription factors by using wheat germ agglutinin affinity chromatography.

1989 • 175 citations

DNA-dependent protein kinase is activated by nicks and larger single-stranded gaps

1994 • 139 citations

DNA binding provides a signal for phosphorylation of the RNA polymerase II heptapeptide repeats.

1992 • 133 citations

Transcription complex formation at the mouse rDNA promoter involves the stepwise association of four transcription factors and RNA polymerase I.

1991 • 125 citations

Identification of Ki (Ku, p70/p80) autoantigens and analysis of anti-Ki autoantibody reactivity.

1986 • 118 citations

Dual role of the nucleolar transcription factor UBF: trans-activator and antirepressor.

1992 • 110 citations

c-Jun is phosphorylated by the DNA-dependent protein kinasein vitro; definition of the minimal kinase recognition motif

1993 • 104 citations

Specific interaction of the murine transcription termination factor TTF I with class-I RNA polymerases

1990 • 104 citations

A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I

1993 • 95 citations

Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter.

1993 • 81 citations

On the mechanisms of ku protein binding to DNA

1992 • 80 citations

The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription

1993 • 80 citations

Promoter-dependent phosphorylation of RNA polymerase II by a template-bound kinase. Association with transcriptional initiation

1991 • 73 citations

A 10S particle released from deoxyribonuclease-sensitive regions of HeLa cell nuclei contains the 86-kilodalton-70-kilodalton protein complex

1986 • 68 citations

TBP-associated factors interact with DNA and govern species specificity of RNA polymerase I transcription.

1994 • 61 citations

Expression of the Ku protein during cell proliferation

1991 • 60 citations

Protein kinases and DNA damage

1994 • 55 citations

Immunolocalization of Ku-proteins (p80/p70): Localization of p70 to nucleoli and periphery of both interphase nuclei and metaphase chromosomes

1992 • 50 citations

TIF-IC, a factor involved in both transcription initiation and elongation of RNA polymerase I.

1994 • 46 citations

Identification of two steps during Xenopus ribosomal gene transcription that are sensitive to protein phosphorylation.

1994 • 10 citations