Promoter-dependent phosphorylation of RNA polymerase II by a template-bound kinase. Association with transcriptional initiation

The “initiator” as a transcription control element

1989 • 1,597 citations

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 • 670 citations

Acid blobs and negative noodles

1988 • 438 citations

RNA Polymerase B (II) And General Transcription Factors

1990 • 355 citations

A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II.

1985 • 346 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

Messenger RNA synthesis in mammalian cells is catalyzed by the phosphorylated form of RNA polymerase II.

1987 • 288 citations

Casein kinase type II is involved in the inhibition by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription.

1986 • 285 citations

Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2

1989 • 270 citations

The C-terminal domain of the largest subunit of RNA polymerase II of Saccharomyces cerevisiae, Drosophila melanogaster, and mammals: a conserved structure with an essential function.

1988 • 246 citations

The transition of RNA polymerase II from initiation to elongation is associated with phosphorylation of the carboxyl-terminal domain of subunit IIa

1989 • 236 citations

Inhibition of in Vivo and in Vitro Transcription by Monoclonal Antibodies Prepared against Wheat Germ RNA Polymerase II That React with the Heptapeptide Repeat of Eukaryotic RNA Polymerase II

1989 • 228 citations

Genetic analysis of the repetitive carboxyl-terminal domain of the largest subunit of mouse RNA polymerase II.

1988 • 212 citations

Mechanism of RNA polymerase II-specific initiation of transcription in vitro: ATP requirement and uncapped runoff transcripts

1982 • 206 citations

Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II

1989 • 193 citations

Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II

1989 • 190 citations

The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro.

1988 • 190 citations

Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription.

1990 • 178 citations

Energy requirement for specific transcription initiation by the human RNA polymerase II system.

1984 • 166 citations

RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals

1990 • 163 citations

Phosphorylation of eukaryotic DNA-dependent RNA polymerase. Identification of calf thymus RNA polymerase subunits phosphorylated by two purified protein kinases, correlation with in vivo sites of phosphorylation in HeLa cell RNA polymerase II.

1981 • 159 citations

Double-stranded DNA induces the phosphorylation of several proteins including the 90 000 mol. wt. heat-shock protein in animal cell extracts.

1985 • 143 citations

Transcription initiation by RNA polymerase II in vitro. Properties of preinitiation, initiation, and elongation complexes.

1987 • 132 citations

An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters.

1989 • 127 citations

RNA contacts subunits IIo and IIc in HeLa RNA polymerase II transcription complexes.

1986 • 126 citations

Mutations in RNA polymerase II enhance or suppress mutations in GAL4.

1989 • 123 citations

A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II.

1989 • 123 citations

ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis.

1988 • 117 citations

Sarkosyl activation of RNA polymerase activity in mitotic mouse cells

1974 • 108 citations

The heptad repeat in the largest subunit of RNA polymerase II binds by intercalating into DNA

1990 • 103 citations

Transcription-dependent Structural Changes in the C-terminal Domain of Mammalian RNA Polymerase Subunit IIa/o

1989 • 97 citations

The Major Late Promoter of Adenovirus-2 Is Accurately Transcribed by RNA Polymerases IIO, IIA, and IIB

1989 • 83 citations

Transcription of adenovirus-2 major late promoter inhibited by monoclonal antibody directed against RNA polymerases IIO and IIA.

1983 • 80 citations

Promoter-dependent Transcription by RNA Polymerase II Using Immobilized Enzyme Complexes

1989 • 69 citations

5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole inhibits a HeLa protein kinase that phosphorylates an RNA polymerase II-derived peptide

1989 • 39 citations

A protein kinase from wheat germ that phosphorylates the largest subunit of RNA polymerase II.

1989 • 37 citations

The C-terminal domain of the largest subunit of RNA polymerase II and transcription initiation.

1989 • 23 citations

Synthesis and degradation of the major hepatic phosphofructokinase isozyme in rat liver and hepatoma 3924-A

1974 • 6 citations