Functional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expression.

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1993 • 828 citations

A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

1984 • 674 citations

The class II molecules of the human and murine major histocompatibility complex

1984 • 664 citations

The High Mobility Group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene

1992 • 632 citations

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

1984 • 564 citations

Sequences and Factors: A Guide to MHC Class-II Transcription

1992 • 540 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon

1983 • 487 citations

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

1987 • 451 citations

Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements

1993 • 440 citations

Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.

1988 • 432 citations

A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein

1988 • 399 citations

Human and Drosophila Homeodomain Proteins That Enhance the DNA-Binding Activity of Serum Response Factor

1992 • 314 citations

Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules.

1983 • 312 citations

SAR-dependent mobilization of histone H1 by HMG-I/Y in vitro: HMG-I/Y is enriched in H1-depleted chromatin.

1993 • 288 citations

HUMAN CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX GENES AND PROTEINS

1988 • 277 citations

Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits.

1990 • 264 citations

Induction of Ia and H-2 antigens on a macrophage cell line by immune interferon.

1983 • 227 citations

Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter

1992 • 225 citations

The DNA-Bending Protein HMG-1 Enhances Progesterone Receptor Binding to Its Target DNA Sequences

1994 • 200 citations

Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter

1993 • 191 citations

A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes

1985 • 191 citations

Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y.

1994 • 176 citations

In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome

1991 • 175 citations

MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain.

1990 • 171 citations

Mature human eosinophils have the capacity to express HLA-DR.

1989 • 164 citations

Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts.

1986 • 159 citations

Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation.

1989 • 141 citations

Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene.

1987 • 126 citations

Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene

1990 • 125 citations

Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos.

1991 • 125 citations

Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors.

1990 • 121 citations

B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene.

1988 • 118 citations

Class II genes of the human major histocompatibility complex. The DO beta gene is a divergent member of the class II beta gene family.

1987 • 115 citations

A Poly(dA-dT) Upstream Activating Sequence Binds High-Mobility Group I Protein and Contributes to Lymphotoxin (Tumor Necrosis Factor-β) Gene Regulation

1992 • 115 citations

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1993 • 107 citations

Sequence-specific interactions of nuclear factors with conserved sequences of human class II major histocompatibility complex genes.

1987 • 103 citations

Distinct Cloned Class II MHC DNA Binding Proteins Recognize the X Box Transcription Element

1988 • 99 citations

A novel cysteine-rich sequence-specific DNA-binding protein interacts with the conserved X-box motif of the human major histocompatibility complex class II genes via a repeated Cys-His domain and functions as a transcriptional repressor.

1994 • 93 citations

Congenital immunodeficiencies associated with absence of HLA class II antigens on lymphocytes result from distinct mutations in trans-acting factors

1989 • 82 citations

Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function.

1991 • 74 citations

In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma.

1992 • 69 citations

Sequence Elements Required for Activity of a Murine Major Histocompatibility Complex Class II Promoter Bind Common and Cell-Type-Specific Nuclear Factors

1990 • 68 citations

Cloning of cDNAs coding for human HMG I and HMG Y proteins: both are capable of binding to the octamer sequence motif

1989 • 66 citations

Cis-acting sequences from mouse rDNA promote plasmid DNA amplification and persistence in mouse cells: implication of HMG-I in their function

1989 • 62 citations

NF-X2 that binds to the DRA X2-box is activator protein 1. Expression cloning of c-Jun.

1990 • 57 citations

Multiple regulatory regions on the 5' side of the mouse E alpha gene.

1988 • 55 citations

Transcription of a subset of human class II major histocompatibility complex genes is regulated by a nucleoprotein complex that contains c-fos or an antigenically related protein.

1991 • 52 citations

The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter.

1989 • 47 citations

An isotype-specific trans-acting factor is defective in a mutant B cell line that expresses HLA-DQ, but not -DR or -DP.

1991 • 47 citations

X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.

1990 • 41 citations

IDDM in BB Rats: Enhanced MHC Class I Heavy-Chain Gene Expression in Pancreatic Islets

1988 • 37 citations

Sequences And Factors: A Guide To Mhc Class-Ii Transcription

1992 • 35 citations

Sequence elements required for activity of a murine major histocompatibility complex class II promoter bind common and cell-type-specific nuclear factors.

1990 • 33 citations

Transcription of HLA Class II Genes in the Absence of B-Cell-Specific Octamer-Binding Factor

1988 • 33 citations

The kappa B enhancer motifs in human immunodeficiency virus type 1 and simian virus 40 recognize different binding activities in human Jurkat and H9 T cells: evidence for NF-kappa B-independent activation of the kappa B motif

1992 • 29 citations

Differential Ia antigen expression by autologous human erythroid and B lymphoblastoid cell lines.

1985 • 27 citations

Stereospecific Alignment of the X and Y Elements Is Required for Major Histocompatibility Complex Class II DRA Promoter Function

1991 • 26 citations

Mapping of the Interaction Site of the Defective Transcription Factor in the Class II Major Histocompatibility Complex Mutant Cell Line Clone-13 to the Divergent X2-Box

1995 • 21 citations

The HLA-DQβ gene upstream region contains an immunoglobulin-like octamer motif that binds cell-type specific nuclear factors

1987 • 19 citations

Transcription of HLA class II genes in the absence of B-cell-specific octamer-binding factor.

1988 • 18 citations

The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA.

1992 • 15 citations

Current concepts in DRA gene regulation

1993 • 15 citations

MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain

1990 • 10 citations

Human Class Ii Major Histocompatibility Complex Genes And Proteins

1988 • 9 citations

Interferon-γ response region in the promoter of the class II MHC gene, DPA

1992 • 7 citations

The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA

1992 • 3 citations

X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.

1990 • 2 citations