Hyperhomocyst(e)inemia and Atherothrombosis^a

The Metabolic Basis of Inherited Disease

1990 • 4,327 citations

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

Vitamin Status and Intake as Primary Determinants of Homocysteinemia in an Elderly Population

1993 • 1,920 citations

Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.

1969 • 1,846 citations

A Prospective Study of Plasma Homocyst(e)ine and Risk of Myocardial Infarction in US Physicians

1992 • 1,686 citations

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Methionine metabolism in mammals

1990 • 1,463 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

1995 • 1,244 citations

Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis.

1976 • 933 citations

Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen.

1993 • 865 citations

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.

1986 • 826 citations

Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis.

1994 • 812 citations

Heterozygosity for Homocystinuria in Premature Peripheral and Cerebral Occlusive Arterial Disease

1985 • 739 citations

Hyperhomocyst(e)inemia as a Risk Factor for Occlusive Vascular Disease

1992 • 726 citations

Homocystinemia

1974 • 655 citations

Generation of Superoxide Free Radical during the Autoxidation of Thiols

1974 • 558 citations

Interaction of γ-Glutamyl Transpeptidase with Amino Acids, Dipeptides, and Derivatives and Analogs of Glutathione

1974 • 541 citations

[2] Thiol/disulfide exchange equilibria and disulfidebond stability

1995 • 535 citations

The pathogenesis of coronary artery disease. A possible role for methionine metabolism.

1976 • 535 citations

Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury

1980 • 489 citations

Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia

1993 • 475 citations

The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.

1987 • 465 citations

Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease Effects of pyridoxine and folic acid treatment

1990 • 397 citations

Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells

1990 • 392 citations

Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensin1 receptors.

1995 • 325 citations

Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells.

1993 • 314 citations

Radioenzymic determination of homocysteine in plasma and urine.

1985 • 310 citations

Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease.

1986 • 307 citations

Moderate homocysteinemia--a possible risk factor for arteriosclerotic cerebrovascular disease.

1984 • 290 citations

The production of free radicals during the autoxidation of cysteine and their effect on isolated rat hepatocytes

1982 • 283 citations

Hyperhomocyst(e)inemia. A common and easily reversible risk factor for occlusive atherosclerosis.

1990 • 266 citations

Oxy-radicals in molecular biology and pathology

1989 • 262 citations

Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells.

1993 • 243 citations

Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons.

1983 • 241 citations

Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity

1972 • 232 citations

Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide.

1995 • 229 citations

Redox Status and Protein Binding of Plasma Homocysteine and Other Aminothiols in Patients With Early-Onset Peripheral Vascular Disease

1995 • 215 citations

Superoxide‐dependent formation of hydroxyl radicals in the presence of thiol compounds

1982 • 214 citations

Plasma sulfhydryl-containing amino acids in patients with cerebral infarction and in hypertensive subjects

1989 • 197 citations

Atherosclerotic Cardiovascular Disease, Hemostasis and Endothelial Function

1993 • 179 citations

Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease

1988 • 175 citations

An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells

1992 • 150 citations

Glutathione peroxidase potentiates the inhibition of platelet function by S-nitrosothiols.

1995 • 148 citations

Methionine intolerance: A possible risk factor for coronary artery disease

1985 • 144 citations

Endothelial cell dysfunction in homocystinuria

1983 • 142 citations

Homocysteinemia, ischemic heart disease, and the carrier state for homocystinuria

1983 • 138 citations

Effect of thiol oxidation and thiol export from erythrocytes on determination of redox status of homocysteine and other thiols in plasma from healthy subjects and patients with cerebral infarction

1995 • 128 citations

An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells

1992 • 121 citations

Activation of Hageman Factor by L-Homocystine

1968 • 116 citations

Arterial endothelial barrier dysfunction: actions of homocysteine and the hypoxanthine‐xanthine oxidase free radical generating system

1993 • 107 citations

Antihuman plasma glutathione peroxidase antibodies: immunologic investigations to determine plasma glutathione peroxidase protein and selenium content in plasma

1989 • 77 citations

Homocysteine Metabolism in Scurvy, Growth and Arteriosclerosis

1971 • 69 citations

Lipid peroxidation and homocysteine induced toxicity

1994 • 69 citations

The spectrum of diseases of small coronery arteries and their physiologic consequences

1990 • 49 citations

Measurement of plasma thiols after derivatization with monobromobimane

1988 • 46 citations

Atheroschlerosis risk factors

1987 • 36 citations

Conversion of methionine to homocysteine thiolactone in liver

1974 • 28 citations

モノブロモビマンによる誘導体化による血しょう中のチオールの定量 | 文献情報 | J-GLOBAL 科学技術総合リンクセンター

1988 • 28 citations

Homocyst(e)ine decreases cell redox potential in vascular smooth muscle cells

1996 • 9 citations

Thromboembolic Disorders

2012 • 7 citations