Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

1991 • 2,191 citations

A Prospective Study of Plasma Homocyst(e)ine and Risk of Myocardial Infarction in US Physicians

1992 • 1,686 citations

The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

1985 • 1,251 citations

Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis.

1976 • 933 citations

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.

1986 • 826 citations

The Regulation of Natural Anticoagulant Pathways

1987 • 702 citations

Homocystinemia

1974 • 655 citations

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity.

1986 • 592 citations

Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury

1980 • 489 citations

Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine.

1991 • 451 citations

Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells

1990 • 392 citations

Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator.

1986 • 390 citations

Cloned bovine aortic endothelial cells synthesize anticoagulantly active heparan sulfate proteoglycan.

1986 • 342 citations

A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians

1992 • 329 citations

The protein C anticoagulant pathway.

1992 • 293 citations

The production of free radicals during the autoxidation of cysteine and their effect on isolated rat hepatocytes

1982 • 283 citations

Hyperhomocyst(e)inemia. A common and easily reversible risk factor for occlusive atherosclerosis.

1990 • 266 citations

Natural anticoagulant mechanisms.

1984 • 251 citations

Isolation and characterization of heparan sulfate proteoglycans produced by cloned rat microvascular endothelial cells.

1992 • 152 citations

An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells

1992 • 150 citations

Human arterial endothelial cell detachment in vitro: its promotion by homocysteine and cysteine

1991 • 113 citations

Vessel proteoglycans and thrombogenesis.

1980 • 110 citations

Biosynthesis of Heparin and Heparan Sulfatea

1989 • 77 citations

Evidence that cell surface heparan sulfate is involved in the high affinity thrombin binding to cultured porcine aortic endothelial cells.

1985 • 72 citations

Human recombinant interleukin‐1β‐ and tumor necrosis factor α‐mediated suppression of heparin‐like compounds on cultured porcine aortic endothelial cells

1990 • 69 citations

Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells

1990 • 38 citations

Modulation of glycosaminoglycan production and antithrombin III binding by cultured aortic endothelial cells treated with 4-methylumbelliferyl-beta-D-xyloside.

1987 • 32 citations

Biosynthesis of Heparin and Heparan Sulfate

1987 • 31 citations

Cell mutants defective in synthesizing a heparan sulfate proteoglycan with regions of defined monosaccharide sequence.

1990 • 27 citations

Histidine-rich glycoprotein does not interfere with interactions between antithrombin III and heparin-like compounds on vascular endothelial cells

1989 • 14 citations

Histidine-rich glycoprotein does not interfere with interactions between antithrombin III and heparin-like compounds on vascular endothelial cells

1989 • 2 citations