Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

2012 • 10,051 citations

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

1998 • 3,377 citations

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

1998 • 1,440 citations

Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo

1997 • 1,283 citations

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

1996 • 974 citations

Structure of the A Site of Escherichia coli 16 S Ribosomal RNA Complexed with an Aminoglycoside Antibiotic

1996 • 782 citations

[22] absorbance melting curves of RNA

1989 • 620 citations

Regulation of gene expression by small molecules

1997 • 465 citations

Synthetic filaments assembled from C‐terminally truncated α‐synuclein

1998 • 408 citations

Recognition of DNA by designed ligands at subnanomolar concentrations

1996 • 391 citations

NMR investigation of RNA structure

1996 • 385 citations

Rapid Assembly of Alzheimer-like Paired Helical Filaments from Microtubule-Associated Protein Tau Monitored by Fluorescence in Solution

1998 • 380 citations

Genetic Classification of Primary Neurodegenerative Disease

1998 • 337 citations

Neurofibrillary Degeneration in Progressive Supranuclear Palsy and Corticobasal Degeneration

1999 • 284 citations

Structure of the P1 Helix from Group I Self-splicing Introns

1995 • 281 citations

Tau Mutations Cause Frontotemporal Dementias

1998 • 267 citations

Filamentous nerve cell inclusions in neurodegenerative diseases

1998 • 261 citations

RNA Sequence Determinants for Aminoglycoside Binding to an A-site rRNA Model Oligonucleotide

1996 • 252 citations

Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17

1999 • 247 citations

Vulnerable neuronal subsets in Alzheimer's and Pick's disease are distinguished by their τ isoform distribution and phosphorylation

1998 • 231 citations

Tau gene mutation in familial progressive subcortical gliosis

1999 • 189 citations

Basis for prokaryotic specificity of action of aminoglycoside antibiotics

1999 • 188 citations

A good antisense molecule is hard to find

1998 • 171 citations

A distinct familial presenile dementia with a novel missense mutation in the tau gene

1999 • 156 citations

Solution structure of the tobramycin–RNA aptamer complex

1998 • 154 citations

Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex

1997 • 138 citations

Saccharide–RNA recognition in a complex formed between neomycin B and an RNA aptamer

1999 • 119 citations

Measurement of diffusion constants for nucleic acids by NMR.

1997 • 118 citations

Structure-Based Discovery of Ligands Targeted to the RNA Double Helix

1997 • 71 citations

Structure-based and combinatorial search for new RNA-binding drugs

1999 • 54 citations

Neuropathological Features of Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17q21–22 (FTDP-17)

1999 • 52 citations

Coordinate-based cluster analysis

1995 • 40 citations