Dissociation of charge movement from calcium release and calcium current in skeletal myotubes by gabapentin

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the α2δ Subunit of a Calcium Channel

1996 • 1,164 citations

Involvement of dihydropyridine receptors in excitation–contraction coupling in skeletal muscle

1987 • 887 citations

Regions of the skeletal muscle dihydropyridine receptor critical for excitation–contraction coupling

1990 • 606 citations

Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor

1996 • 449 citations

Dual Function of the Voltage-Dependent Ca2+ Channel α2δ Subunit in Current Stimulation and Subunit Interaction

1996 • 287 citations

Effects of glycerol treatment and maintained depolarization on charge movement in skeletal muscle.

1976 • 267 citations

Intramembrane charge movement restored in dysgenic skeletal muscle by injection of dihydropyridine receptor cDNAs

1990 • 263 citations

Subunit Identification and Reconstitution of the N-Type Ca ²⁺ Channel Complex Purified from Brain

1993 • 255 citations

Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies

1993 • 227 citations

Gabapentin inhibits calcium currents in isolated rat brain neurons

1998 • 204 citations

Time course of calcium release and removal in skeletal muscle fibers

1984 • 159 citations

Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics

1991 • 145 citations

Identification of Calcium Release-triggering and Blocking Regions of the II-III Loop of the Skeletal Muscle Dihydropyridine Receptor

1995 • 144 citations

A 37-Amino Acid Sequence in the Skeletal Muscle Ryanodine Receptor Interacts with the Cytoplasmic Loop between Domains II and III in the Skeletal Muscle Dihydropyridine Receptor

1998 • 116 citations

Structural requirement of the calcium-channel subunit α2δ for gabapentin binding

1999 • 113 citations

Relationship of calcium transients to calcium currents and charge movements in myotubes expressing skeletal and cardiac dihydropyridine receptors.

1994 • 113 citations

Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture

1994 • 86 citations

Influence of L-type Ca channel alpha 2/delta-subunit on ionic and gating current in transiently transfected HEK 293 cells

1996 • 83 citations

Two Amino Acid Residues in the IIIS5 Segment of L-Type Calcium Channels Differentially Contribute to 1,4-Dihydropyridine Sensitivity

1996 • 81 citations

Differential effect of gabapentin on neuronal and muscle calcium currents.

2001 • 81 citations

Measurement of calcium transients and slow calcium current in myotubes.

1994 • 75 citations

Cloning and Deletion Mutagenesis of the α2δ Calcium Channel Subunit from Porcine Cerebral Cortex

1998 • 72 citations

Inactivation of Gating Currents of L-Type Calcium Channels

1998 • 57 citations

Identification and functional characterization of a calcium channel γ subunit

1997 • 55 citations

Single calcium channel behavior in native skeletal muscle.

1995 • 50 citations

Malignant hyperthermia mutation Arg615Cys in the porcine ryanodine receptor alters voltage dependence of Ca²⁺ release

2000 • 49 citations

Effects of perchlorate on the molecules of excitation-contraction coupling of skeletal and cardiac muscle.

1993 • 49 citations

Perchlorate and the relationship between charge movement and contractile activation in frog skeletal muscle fibres.

1987 • 43 citations

Dihydropyridine‐induced Ca²⁺ release from ryanodine‐sensitive Ca²⁺ pools in human skeletal muscle cells

2000 • 39 citations

Effect of the calcium buffer EGTA on the "hump" component of charge movement in skeletal muscle.

1991 • 32 citations

Expression of the α2δ Subunit Interferes with Prepulse Facilitation in Cardiac L-type Calcium Channels

2000 • 30 citations

Effects of gallopamil on calcium release and intramembrane charge movements in frog skeletal muscle fibres.

1990 • 30 citations

Differential effects of ryanodine and tetracaine on charge movement and calcium transients in frog skeletal muscle.

1991 • 28 citations

Imperatoxin A Enhances Ca2+ Release in Developing Skeletal Muscle Containing Ryanodine Receptor Type 3

2002 • 25 citations

Effects of perchlorate on excitation‐contraction coupling in frog and crayfish skeletal muscle.

1992 • 19 citations

Intramembrane charge movement in developing skeletal muscle cells from fetal mice

1992 • 13 citations

Effects of nifedipine and Bay K 8644 on contractile activities in single skeletal muscle fibers of the frog

1994 • 12 citations

Charge movements in intact amphibian skeletal muscle fibres in the presence of cardiac glycosides

2001 • 8 citations