Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture

A simplified method of evaluating dose-effect experiments.

1948 • 7,047 citations

Comparison of Carbamazepine, Phenobarbital, Phenytoin, and Primidone in Partial and Secondarily Generalized Tonic–Clonic Seizures

1985 • 1,149 citations

Antiepileptic Drug Development: II. Anticonvulsant Drug Screening

1978 • 821 citations

A Comparison of Valproate with Carbamazepine for the Treatment of Complex Partial Seizures and Secondarily Generalized Tonic–Clonic Seizures in Adults

1992 • 685 citations

New anticonvulsant drugs

1987 • 314 citations

Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.

1986 • 272 citations

Pharmacokinetics and metabolism of gabapentin in rat, dog and man.

1986 • 268 citations

Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture.

1986 • 237 citations

Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells.

1985 • 225 citations

Gabapentin in partial epilepsy

1990 • 205 citations

Multiple actions of phenytoin on mouse spinal cord neurons in cell culture.

1983 • 202 citations

Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain

1991 • 191 citations

Double‐Blind Study of Gabapentin in the Treatment of Partial Seizures

1991 • 176 citations

Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine.

1982 • 173 citations

Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. 1993.

2001 • 164 citations

Potent and stereospecific anticonvulsant activity of 3-isobutyl GABA relates to in vitro binding at a novel site labeled by tritiated gabapentin

1993 • 145 citations

Antiepileptic Drugs (3rd Ed.)

1990 • 138 citations

Gabapentin as an antiepileptic drug in man.

1987 • 125 citations

Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: Are there common or different sites of action?

1983 • 97 citations

Selected CSF biochemistry and gabapentin concentrations in the CSF and plasma in patients with partial seizures after a single oral dose of gabapentin

1992 • 79 citations

Development of tolerance to the effects of vigabatrin (γ‐vinyl‐GABA) on GABA release from rat cerebral cortex, spinal cord and retina

1990 • 76 citations

Calcium- and sodium-dependent action potentials of mouse spinal cord and dorsal root ganglion neurons in cell culture.

1982 • 67 citations

Benzodiazepines, but not beta carbolines, limit high frequency repetitive firing of action potentials of spinal cord neurons in cell culture.

1988 • 67 citations

Effects of Vigabatrin (γ‐vinyl GAB A) on Neuro transmission‐Related Amino Acids and on GAB A nd Benzodiazepine Receptor Binding in Rats

1991 • 60 citations

Mechanisms of anticonvulsant drug action

1987 • 44 citations

Mechanisms of anticonvulsant drug action.

1987 • 40 citations

[3H]Phenytoin identifies a novel anticonvulsant-binding domain on voltage-dependent sodium channels.

1992 • 26 citations

γ‐Vinyl GABA (Vigabatrin) in Epilepsy: Clinical, Neurochemical, and Neurophysiologic Monitoring in Epileptic Patients

1992 • 26 citations

Use-, concentration- and voltage-dependent limitation by MK-801 of action potential firing frequency in mouse central neurons in cell culture.

1992 • 22 citations

Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-α-benzoate binding in vitro

1991 • 16 citations

Single pyramidal-tract fiber analysis of neocortical propagated seizures with reference to inactivation responses☆

1974 • 13 citations

Deleted Work

1955 • 0 citations